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The search results on this publication page are automated on a monthly schedule based on acknowledgement of NIH Common Fund award numbers and intramural awards. Therefore, this list is not an exhaustive or error-free account of the program’s publications.

Title Authors Journal PubMedID Publication Date
Visualizing a protein quake with time-resolved X-ray scattering at a free-electron laser. Arnlund, David; Johansson, Linda C; Wickstrand, Cecilia; Barty, Anton; Williams, Garth J; Malmerberg, Erik; Davidsson, Jan; Milathianaki, Despina; DePonte, Daniel P; Shoeman, Robert L; Wang, Dingjie; James, Daniel; Katona, Gergely; Westenhoff, Sebastian; Nature methods 25108686 2014 Sep
Tetra detector analysis of membrane proteins. Miercke, Larry J W; Robbins, Rebecca A; Stroud, Robert M Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 25081744 2014
A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR). Hildebrandt, Ellen; Zhang, Qinghai; Cant, Natasha; Ding, Haitao; Dai, Qun; Peng, Lingling; Fu, Yu; DeLucas, Lawrence J; Ford, Robert; Kappes, John C; Urbatsch, Ina L Biochimica et biophysica acta 25065669 2014 Jul 24
Renaturing membrane proteins in the lipid cubic phase, a nanoporous membrane mimetic. Li, Dianfan; Caffrey, Martin Scientific reports 25055873 2014
A new broadband homonuclear mixing pulse for NMR with low applied power. Coote, Paul; Leigh, Kendra E; Yu, Tsyr-Yan; Khaneja, Navin; Wagner, Gerhard; Arthanari, Haribabu The Journal of chemical physics 25028012 2014 Jul 14
Cellular solid-state NMR investigation of a membrane protein using dynamic nuclear polarization. Yamamoto, Kazutoshi; Caporini, Marc A; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy Biochimica et biophysica acta 25017802 2014 Jul 11
NMR Polypeptide Backbone Conformation of the E.ýýcoli Outer Membrane Protein W. Horst, Reto; Stanczak, Pawel; Wuthrich, Kurt Structure (London, England : 1993) 25017731 2014 Aug 5
Cell-free expression and in meso crystallisation of an integral membrane kinase for structure determination. Boland, Coilin; Li, Dianfan; Shah, Syed Tasadaque Ali; Haberstock, Stefan; Dotsch, Volker; Bernhard, Frank; Caffrey, Martin Cellular and molecular life sciences : CMLS 25012698 2014 Jul 11
Structural basis for Smoothened receptor modulation and chemoresistance to anticancer drugs. Wang, Chong; Wu, Huixian; Evron, Tama; Vardy, Eyal; Han, Gye Won; Huang, Xi-Ping; Hufeisen, Sandy J; Mangano, Thomas J; Urban, Dan J; Katritch, Vsevolod; Cherezov, Vadim; Caron, Marc G; Roth, Bryan L; Stevens, Raymond C Nature communications 25008467 2014
'Hit and run' serial femtosecond crystallography of a membrane kinase in the lipid cubic phase. Caffrey, Martin; Li, Dianfan; Howe, Nicole; Shah, Syed T A Philosophical transactions of the Royal Society of London. Series B, Biological sciences 24914170 2014 Jul 17
7 A resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source. Pedrini, Bill; Tsai, Ching-Ju; Capitani, Guido; Padeste, Celestino; Hunter, Mark S; Zatsepin, Nadia A; Barty, Anton; Benner, W Henry; Boutet, Sebastien; Feld, Geoffrey K; Hau-Riege, Stefan P; Kirian, Richard A; Kupitz, Christopher; Messerschmitt, Marc; Og Philosophical transactions of the Royal Society of London. Series B, Biological sciences 24914166 2014 Jul 17
Microcrystallization techniques for serial femtosecond crystallography using photosystem II from Thermosynechococcus elongatus as a model system. Kupitz, Christopher; Grotjohann, Ingo; Conrad, Chelsie E; Roy-Chowdhury, Shatabdi; Fromme, Raimund; Fromme, Petra Philosophical transactions of the Royal Society of London. Series B, Biological sciences 24914149 2014 Jul 17
Femtosecond crystallography of membrane proteins in the lipidic cubic phase. Liu, Wei; Wacker, Daniel; Wang, Chong; Abola, Enrique; Cherezov, Vadim Philosophical transactions of the Royal Society of London. Series B, Biological sciences 24914147 2014 Jul 17
Real-time conformational changes in LacY. Smirnova, Irina; Kasho, Vladimir; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 24872451 2014 Jun 10
The Use of Amphipols for NMR Structural Characterization of 7-TM Proteins. Elter, Shantha; Raschle, Thomas; Arens, Sabine; Viegas, Aldino; Gelev, Vladimir; Etzkorn, Manuel; Wagner, Gerhard The Journal of membrane biology 24858950 2014 May 25
Probing the transmembrane structure and dynamics of microsomal NADPH-cytochrome P450 oxidoreductase by solid-state NMR. Huang, Rui; Yamamoto, Kazutoshi; Zhang, Meng; Popovych, Nataliya; Hung, Ivan; Im, Sang-Choul; Gan, Zhehong; Waskell, Lucy; Ramamoorthy, Ayyalusamy Biophysical journal 24853741 2014 May 20
Applications of the second virial coefficient: protein crystallization and solubility. Wilson, William W; Delucas, Lawrence J Acta crystallographica. Section F, Structural biology communications 24817708 2014 May
3D (15)N/(15)N/(1)H chemical shift correlation experiment utilizing an RFDR-based (1)H/(1)H mixing period at 100kHz MAS. Nishiyama, Yusuke; Malon, Michal; Ishii, Yuji; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 24801998 2014 Apr 19
Performance of RINEPT is amplified by dipolar couplings under ultrafast MAS conditions. Zhang, Rongchun; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 24792960 2014 Jun
Finite-pulse radio frequency driven recoupling with phase cycling for 2D (1)H/(1)H correlation at ultrafast MAS frequencies. Nishiyama, Yusuke; Zhang, Rongchun; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 24713171 2014 Jun
Substrate-induced changes in the structural properties of LacY. Serdiuk, Tetiana; Madej, M Gregor; Sugihara, Junichi; Kawamura, Shiho; Mari, Stefania A; Kaback, H Ronald; Muller, Daniel J Proceedings of the National Academy of Sciences of the United States of America 24711390 2014 Apr 22
An RNA-seq method for defining endoribonuclease cleavage specificity identifies dual rRNA substrates for toxin MazF-mt3. Schifano, Jason M; Vvedenskaya, Irina O; Knoblauch, Jared G; Ouyang, Ming; Nickels, Bryce E; Woychik, Nancy A Nature communications 24709835 2014
Characterization of the type 2 NADH:menaquinone oxidoreductases from Staphylococcus aureus and the bactericidal action of phenothiazines. Schurig-Briccio, Lici A; Yano, Takahiro; Rubin, Harvey; Gennis, Robert B Biochimica et biophysica acta 24709059 2014 Jul
Engineering cells to improve protein expression. Xiao, Su; Shiloach, Joseph; Betenbaugh, Michael J Current opinion in structural biology 24704806 2014 Jun
Solution-NMR characterization of outer-membrane protein A from E. coli in lipid bilayer nanodiscs and detergent micelles. Susac, Lukas; Horst, Reto; Wuthrich, Kurt Chembiochem : a European journal of chemical biology 24692152 2014 May 5
Proton-detected 2D radio frequency driven recoupling solid-state NMR studies on micelle-associated cytochrome-b5. Pandey, Manoj Kumar; Vivekanandan, Subramanian; Yamamoto, Kazutoshi; Im, Sangchoul; Waskell, Lucy; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 24657390 2014 May
Effects of protein engineering and rational mutagenesis on crystal lattice of single chain antibody fragments. Kalyoncu, Sibel; Hyun, Jeongmin; Pai, Jennifer C; Johnson, Jennifer L; Entzminger, Kevin; Jain, Avni; Heaner Jr, David P; Morales, Ivan A; Truskett, Thomas M; Maynard, Jennifer A; Lieberman, Raquel L Proteins 24615866 2014 Feb 26
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer. Monk, Brian C; Tomasiak, Thomas M; Keniya, Mikhail V; Huschmann, Franziska U; Tyndall, Joel D A; O'Connell 3rd, Joseph D; Cannon, Richard D; McDonald, Jeffrey G; Rodriguez, Andrew; Finer-Moore, Janet S; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 24613931 2014 Mar 11
Structure of a class C GPCR metabotropic glutamate receptor 1 bound to an allosteric modulator. Wu, Huixian; Wang, Chong; Gregory, Karen J; Han, Gye Won; Cho, Hyekyung P; Xia, Yan; Niswender, Colleen M; Katritch, Vsevolod; Meiler, Jens; Cherezov, Vadim; Conn, P Jeffrey; Stevens, Raymond C Science (New York, N.Y.) 24603153 2014 Apr 4
A transient interaction between the phosphate binding loop and switch I contributes to the allosteric network between receptor and nucleotide in G*i1. Thaker, Tarjani M; Sarwar, Maruf; Preininger, Anita M; Hamm, Heidi E; Iverson, T M The Journal of biological chemistry 24596087 2014 Apr 18
Direct phasing in femtosecond nanocrystallography. I. Diffraction characteristics. Chen, Joe P J; Spence, John C H; Millane, Rick P Acta crystallographica. Section A, Foundations and advances 24572315 2014 Mar
Functional architecture of MFS D-glucose transporters. Madej, M Gregor; Sun, Linfeng; Yan, Nieng; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 24550316 2014 Feb 18
Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Weierstall, Uwe; James, Daniel; Wang, Chong; White, Thomas A; Wang, Dingjie; Liu, Wei; Spence, John C H; Bruce Doak, R; Nelson, Garrett; Fromme, Petra; Fromme, Raimund; Grotjohann, Ingo; Kupitz, Christopher; Zatsepin, Nadia A; Liu, Haiguang; Basu, Shibom; Nature communications 24525480 2014 Feb 14
23S rRNA as an a-Maz-ing new bacterial toxin target. Schifano, Jason M; Woychik, Nancy A RNA biology 24525465 2014 Feb
Drug screening strategy for human membrane proteins: from NMR protein backbone structure to in silica- and NMR-screened hits. Lindert, Steffen; Maslennikov, Innokentiy; Chiu, Ellis J C; Pierce, Levi C; McCammon, J Andrew; Choe, Senyon Biochemical and biophysical research communications 24525125 2014 Mar 21
Galactoside-binding site in LacY. Jiang, Xiaoxu; Villafuerte, Maria Katerina R; Andersson, Magnus; White, Stephen H; Kaback, H Ronald Biochemistry 24520888 2014 Mar 11
Protein and lipid interactions driving molecular mechanisms of in meso crystallization. Johner, Niklaus; Mondal, Sayan; Morra, Giulia; Caffrey, Martin; Weinstein, Harel; Khelashvili, George Journal of the American Chemical Society 24494670 2014 Feb 26
Dynafold: a dynamic programming approach to protein backbone structure determination from minimal sets of Residual Dipolar Couplings. Mukhopadhyay, Rishi; Irausquin, Stephanie; Schmidt, Christopher; Valafar, Homayoun Journal of bioinformatics and computational biology 24467760 2014 Feb
Bicelles exhibiting magnetic alignment for a broader range of temperatures: a solid-state NMR study. Yamamoto, Kazutoshi; Pearcy, Paige; Ramamoorthy, Ayyalusamy Langmuir : the ACS journal of surfaces and colloids 24460179 2014 Feb 18
Structure of sugar-bound LacY. Kumar, Hemant; Kasho, Vladimir; Smirnova, Irina; Finer-Moore, Janet S; Kaback, H Ronald; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 24453216 2014 Feb 4
Doc toxin is a kinase that inactivates elongation factor Tu. Cruz, Jonathan W; Rothenbacher, Francesca P; Maehigashi, Tatsuya; Lane, William S; Dunham, Christine M; Woychik, Nancy A The Journal of biological chemistry 24448800 2014 Mar 14
Back to the future: recombinant polyclonal antibody therapeutics. Wang, Xian-Zhe; Coljee, Vincent W; Maynard, Jennifer A Current opinion in chemical engineering 24443710 2013 Nov
Molecular control of ýý-opioid receptor signalling. Fenalti, Gustavo; Giguere, Patrick M; Katritch, Vsevolod; Huang, Xi-Ping; Thompson, Aaron A; Cherezov, Vadim; Roth, Bryan L; Stevens, Raymond C Nature 24413399 2014 Jan 12
Rational design of a structural framework with potential use to develop chemical reagents that target and modulate multiple facets of Alzheimer's disease. Lee, Sanghyun; Zheng, Xueyun; Krishnamoorthy, Janarthanan; Savelieff, Masha G; Park, Hyun Min; Brender, Jeffrey R; Kim, Jin Hoon; Derrick, Jeffrey S; Kochi, Akiko; Lee, Hyuck Jin; Kim, Cheal; Ramamoorthy, Ayyalusamy; Bowers, Michael T; Lim, Mi Hee Journal of the American Chemical Society 24397771 2014 Jan 8
Modulation of raft domains in a lipid bilayer by boundary-active curcumin. Tsukamoto, Manami; Kuroda, Kenichi; Ramamoorthy, Ayyalusamy; Yasuhara, Kazuma Chemical communications (Cambridge, England) 24396862 2014 Apr 4
Structure-based mechanism for Na(+)/melibiose symport by MelB. Ethayathulla, Abdul S; Yousef, Mohammad S; Amin, Anowarul; Leblanc, Gerard; Kaback, H Ronald; Guan, Lan Nature communications 24389923 2014
Protein structural ensembles are revealed by redefining X-ray electron density noise. Lang, P Therese; Holton, James M; Fraser, James S; Alber, Tom Proceedings of the National Academy of Sciences of the United States of America 24363322 2014 Jan 7
Serial femtosecond crystallography of G protein-coupled receptors. Liu, Wei; Wacker, Daniel; Gati, Cornelius; Han, Gye Won; James, Daniel; Wang, Dingjie; Nelson, Garrett; Weierstall, Uwe; Katritch, Vsevolod; Barty, Anton; Zatsepin, Nadia A; Li, Dianfan; Messerschmidt, Marc; Boutet, Sebastien; Williams, Garth J; Koglin, J Science (New York, N.Y.) 24357322 2013 Dec 20
Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels. Zhao, Jun; Hu, Rundong; Sciacca, Michele F M; Brender, Jeffrey R; Chen, Hong; Ramamoorthy, Ayyalusamy; Zheng, Jie Physical chemistry chemical physics : PCCP 24352606 2014 Jan 15
Structure of a photosynthetic reaction centre determined by serial femtosecond crystallography. Johansson, Linda C; Arnlund, David; Katona, Gergely; White, Thomas A; Barty, Anton; DePonte, Daniel P; Shoeman, Robert L; Wickstrand, Cecilia; Sharma, Amit; Williams, Garth J; Aquila, Andrew; Bogan, Michael J; Caleman, Carl; Davidsson, Jan; Doak, R Bruce; Nature communications 24352554 2013
Hydrophobic variations of N-oxide amphiphiles for membrane protein manipulation: importance of non-hydrocarbon groups in the hydrophobic portion. Chae, Pil Seok; Sadaf, Aiman; Gellman, Samuel H Chemistry, an Asian journal 24347070 2014 Jan
A small molecule that displays marked reactivity toward copper- versus zinc-amyloid-* implicated in Alzheimer's disease. Savelieff, Masha G; Liu, Yuzhong; Senthamarai, Russell R P; Korshavn, Kyle J; Lee, Hyuck Jin; Ramamoorthy, Ayyalusamy; Lim, Mi Hee Chemical communications (Cambridge, England) 24326305 2013 Dec 10
Predicting the X-ray lifetime of protein crystals. Zeldin, Oliver B; Brockhauser, Sandor; Bremridge, John; Holton, James M; Garman, Elspeth F Proceedings of the National Academy of Sciences of the United States of America 24297937 2013 Dec 17
Insights into Atomic-Level Interaction between Mefenamic Acid and Eudragit EPO in a Supersaturated Solution by High-Resolution Magic-Angle Spinning NMR Spectroscopy. Higashi, Kenjirou; Yamamoto, Kazutoshi; Pandey, Manoj Kumar; Mroue, Kamal H; Moribe, Kunikazu; Yamamoto, Keiji; Ramamoorthy, Ayyalusamy Molecular pharmaceutics 24283196 2014 Jan 6
Using macromolecular-crystallography beamline and microfluidic platform for small-angle diffraction studies of lipidic matrices for membrane-protein crystallization. Kondrashkina, E; Khvostichenko, D S; Perry, S L; Von Osinski, J; Kenis, P J A; Brister, K Journal of physics. Conference series 24260038 2013
Evolutionary mix-and-match with MFS transporters II. Madej, M Gregor; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 24259711 2013 Dec 10
Shortening spin-lattice relaxation using a copper-chelated lipid at low-temperatures - A magic angle spinning solid-state NMR study on a membrane-bound protein. Yamamoto, Kazutoshi; Caporini, Marc A; Im, Sangchoul; Waskell, Lucy; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 24246881 2013 Dec
High-resolution NMR reveals secondary structure and folding of amino acid transporter from outer chloroplast membrane. Zook, James D; Molugu, Trivikram R; Jacobsen, Neil E; Lin, Guangxin; Soll, Jurgen; Cherry, Brian R; Brown, Michael F; Fromme, Petra PloS one 24205117 2013
Crystallization of the large membrane protein complex photosystem I in a microfluidic channel. Abdallah, Bahige G; Kupitz, Christopher; Fromme, Petra; Ros, Alexandra ACS nano 24191698 2013 Dec 23
Structures of intermediate transport states of ZneA, a Zn(II)/proton antiporter. Pak, John Edward; Ekende, Elisabeth Ngonlong; Kifle, Efrem G; O'Connell 3rd, Joseph Daniel; De Angelis, Fabien; Tessema, Meseret B; Derfoufi, Kheiro-Mouna; Robles-Colmenares, Yaneth; Robbins, Rebecca A; Goormaghtigh, Erik; Vandenbussche, Guy; Stroud, Robe Proceedings of the National Academy of Sciences of the United States of America 24173033 2013 Nov 12
Novel tripod amphiphiles for membrane protein analysis. Chae, Pil Seok; Kruse, Andrew C; Gotfryd, Kamil; Rana, Rohini R; Cho, Kyung Ho; Rasmussen, Soren G F; Bae, Hyoung Eun; Chandra, Richa; Gether, Ulrik; Guan, Lan; Kobilka, Brian K; Loland, Claus J; Byrne, Bernadette; Gellman, Samuel H Chemistry (Weinheim an der Bergstrasse, Germany) 24123610 2013 Nov 11
Cytochrome-P450-cytochrome-b5 interaction in a membrane environment changes 15N chemical shift anisotropy tensors. Pandey, Manoj Kumar; Vivekanandan, Subramanian; Ahuja, Shivani; Huang, Rui; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 24107224 2013 Nov 7
(1)H, (13)C and (15)N resonance assignments for the full-length mammalian cytochrome b5 in a membrane environment. Vivekanandan, Subramanian; Ahuja, Shivani; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy Biomolecular NMR assignments 24105099 2013 Oct 9
Impact of histidine residues on the transmembrane helices of viroporins. Wang, Yan; Park, Sang Ho; Tian, Ye; Opella, Stanley J Molecular membrane biology 24102567 2013 Nov
Radiation damage in protein serial femtosecond crystallography using an x-ray free-electron laser. Lomb, Lukas; Barends, Thomas R M; Kassemeyer, Stephan; Aquila, Andrew; Epp, Sascha W; Erk, Benjamin; Foucar, Lutz; Hartmann, Robert; Rudek, Benedikt; Rolles, Daniel; Rudenko, Artem; Shoeman, Robert L; Andreasson, Jakob; Bajt, Sasa; Barthelmess, Miriam; Ba Physical review. B, Condensed matter and materials physics 24089594 2011 Dec 1
Self-terminating diffraction gates femtosecond X-ray nanocrystallography measurements. Barty, Anton; Caleman, Carl; Aquila, Andrew; Timneanu, Nicusor; Lomb, Lukas; White, Thomas A; Andreasson, Jakob; Arnlund, David; Bajt, Sasa; Barends, Thomas R M; Barthelmess, Miriam; Bogan, Michael J; Bostedt, Christoph; Bozek, John D; Coffee, Ryan; Coppo Nature photonics 24078834 2012
Hydrophobic variants of ganglio-tripod amphiphiles for membrane protein manipulation. Chae, Pil Seok; Cho, Kyung Ho; Wander, Marc J; Bae, Hyoung Eun; Gellman, Samuel H; Laible, Philip D Biochimica et biophysica acta 24064323 2014 Jan
The N-Terminal Sequence of Tyrosine Hydroxylase Is a Conformationally Versatile Motif That Binds 14-3-3 Proteins and Membranes. Skjevik, Age Aleksander; Mileni, Mauro; Baumann, Anne; Halskau, Oyvind; Teigen, Knut; Stevens, Raymond C; Martinez, Aurora Journal of molecular biology 24055376 2013 Sep 17
Membrane protein structure determination in membrana. Ding, Yi; Yao, Yong; Marassi, Francesca M Accounts of chemical research 24041243 2013 Sep 17
Dielectrophoretic sorting of membrane protein nanocrystals. Abdallah, Bahige G; Chao, Tzu-Chiao; Kupitz, Christopher; Fromme, Petra; Ros, Alexandra ACS nano 24004002 2013 Oct 22
Optimizing E. coli-based membrane protein production using Lemo21(DE3) and GFP-fusions. Hjelm, Anna; Schlegel, Susan; Baumgarten, Thomas; Klepsch, Mirjam; Wickstrom, David; Drew, David; de Gier, Jan-Willem Methods in molecular biology (Clifton, N.J.) 23996190 2013
Probing the transmembrane structure and topology of microsomal cytochrome-p450 by solid-state NMR on temperature-resistant bicelles. Yamamoto, Kazutoshi; Gildenberg, Melissa; Ahuja, Shivani; Im, Sang-Choul; Pearcy, Paige; Waskell, Lucy; Ramamoorthy, Ayyalusamy Scientific reports 23989972 2013 Aug 30
Dynamic interaction between membrane-bound full-length cytochrome P450 and cytochrome b5 observed by solid-state NMR spectroscopy. Yamamoto, Kazutoshi; Durr, Ulrich H N; Xu, Jiadi; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy Scientific reports 23985776 2013
Membrane protein structure determination: back to the membrane. Yao, Yong; Ding, Yi; Tian, Ye; Opella, Stanley J; Marassi, Francesca M Methods in molecular biology (Clifton, N.J.) 23975776 2013
Measuring transmembrane helix interaction strengths in lipid bilayers using steric trapping. Hong, Heedeok; Chang, Yu-Chu; Bowie, James U Methods in molecular biology (Clifton, N.J.) 23975771 2013
Host Lipid and Temperature as Important Screening Variables for Crystallizing Integral Membrane Proteins in Lipidic Mesophases. Trials with Diacylglycerol Kinase. Li, Dianfan; Shah, Syed T A; Caffrey, Martin Crystal growth & design 23956688 2013 Jul 3
*ýýý-adrenergic receptor activation by agonists studied with ýýýýýF NMR spectroscopy. Horst, Reto; Liu, Jeffrey J; Stevens, Raymond C; Wuthrich, Kurt Angewandte Chemie (International ed. in English) 23956158 2013 Oct 4
Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs. Didenko, Tatiana; Liu, Jeffrey J; Horst, Reto; Stevens, Raymond C; Wuthrich, Kurt Current opinion in structural biology 23932201 2013 Oct
YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery. Zhu, Lu; Kaback, H Ronald; Dalbey, Ross E The Journal of biological chemistry 23928306 2013 Sep 27
In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2-x)/ZnS Core/Shell Quantum Dots. Panthani, Matthew G; Khan, Tarik A; Reid, Dariya K; Hellebusch, Daniel J; Rasch, Michael R; Maynard, Jennifer A; Korgel, Brian A Nano letters 23915166 2013 Aug 9
The silent codon change I507-ATC->ATT contributes to the severity of the ýýF508 CFTR channel dysfunction. Lazrak, Ahmed; Fu, Lianwu; Bali, Vedrana; Bartoszewski, Rafal; Rab, Andras; Havasi, Viktoria; Keiles, Steve; Kappes, John; Kumar, Ranjit; Lefkowitz, Elliot; Sorscher, Eric J; Matalon, Sadis; Collawn, James F; Bebok, Zsuzsanna FASEB journal : official publication of the Federation of American Societies for Experimental Biology 23907436 2013 Nov
Structure of the human glucagon class B G-protein-coupled receptor. Siu, Fai Yiu; He, Min; de Graaf, Chris; Han, Gye Won; Yang, Dehua; Zhang, Zhiyun; Zhou, Caihong; Xu, Qingping; Wacker, Daniel; Joseph, Jeremiah S; Liu, Wei; Lau, Jesper; Cherezov, Vadim; Katritch, Vsevolod; Wang, Ming-Wei; Stevens, Raymond C Nature 23863937 2013 Jul 25
The hepatitis B virus preS1 domain hijacks host trafficking proteins by motif mimicry. Jurgens, Maike C; Voros, Judit; Rautureau, Gilles J P; Shepherd, Dale A; Pye, Valerie E; Muldoon, Jimmy; Johnson, Christopher M; Ashcroft, Alison E; Freund, Stefan M V; Ferguson, Neil Nature chemical biology 23851574 2013 Sep
Three-Dimensional Structure and Interaction Studies of Hepatitis C Virus p7 in 1,2-Dihexanoyl-sn-glycero-3-phosphocholine by Solution Nuclear Magnetic Resonance. Cook, Gabriel A; Dawson, Lindsay A; Tian, Ye; Opella, Stanley J Biochemistry 23841474 2013 Jul 24
Engineered nanostructured ýý-sheet peptides protect membrane proteins. Tao, Houchao; Lee, Sung Chang; Moeller, Arne; Roy, Rituparna Sinha; Siu, Fai Yiu; Zimmermann, Jorg; Stevens, Raymond C; Potter, Clinton S; Carragher, Bridget; Zhang, Qinghai Nature methods 23817067 2013 Aug
Tripod Amphiphiles for Membrane Protein Manipulation. Chae, Pil Seok; Laible, Philip D; Gellman, Samuel H Molecular bioSystems 23814603 2010
Crystallographic data processing for free-electron laser sources. White, Thomas A; Barty, Anton; Stellato, Francesco; Holton, James M; Kirian, Richard A; Zatsepin, Nadia A; Chapman, Henry N Acta crystallographica. Section D, Biological crystallography 23793149 2013 Jul
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases. Riley, B E; Lougheed, J C; Callaway, K; Velasquez, M; Brecht, E; Nguyen, L; Shaler, T; Walker, D; Yang, Y; Regnstrom, K; Diep, L; Zhang, Z; Chiou, S; Bova, M; Artis, D R; Yao, N; Baker, J; Yednock, T; Johnston, J A Nature communications 23770887 2013
Improved production of membrane proteins in Escherichia coli by selective codon substitutions. Norholm, Morten H H; Toddo, Stephen; Virkki, Minttu T I; Light, Sara; von Heijne, Gunnar; Daley, Daniel O FEBS letters 23769986 2013 Aug 2
Integrated nonlinear optical imaging microscope for on-axis crystal detection and centering at a synchrotron beamline. Madden, Jeremy T; Toth, Scott J; Dettmar, Christopher M; Newman, Justin A; Oglesbee, Robert A; Hedderich, Hartmut G; Everly, R Michael; Becker, Michael; Ronau, Judith A; Buchanan, Susan K; Cherezov, Vadim; Morrow, Marie E; Xu, Shenglan; Ferguson, Dale; Ma Journal of synchrotron radiation 23765294 2013 Jul 1
The Structure of the Mercury Transporter MerF in Phospholipid Bilayers: A Large Conformational Rearrangement Results from N-Terminal Truncation. Lu, George J; Tian, Ye; Vora, Nemil; Marassi, Francesca M; Opella, Stanley J Journal of the American Chemical Society 23763519 2013 Jun 26
Advances in NMR structures of integral membrane proteins. Maslennikov, Innokentiy; Choe, Senyon Current opinion in structural biology 23721747 2013 Aug
A model of the membrane-bound cytochrome b5-cytochrome P450 complex from NMR and mutagenesis data. Ahuja, Shivani; Jahr, Nicole; Im, Sang-Choul; Vivekanandan, Subramanian; Popovych, Nataliya; Le Clair, Stephanie V; Huang, Rui; Soong, Ronald; Xu, Jiadi; Yamamoto, Kazutoshi; Nanga, Ravi P; Bridges, Angela; Waskell, Lucy; Ramamoorthy, Ayyalusamy The Journal of biological chemistry 23709268 2013 Jul 26
Thermostabilisation of the serotonin transporter in a cocaine-bound conformation. Abdul-Hussein, Saba; Andrell, Juni; Tate, Christopher G Journal of molecular biology 23706649 2013 Jun 26
Structural basis for alternating access of a eukaryotic calcium/proton exchanger. Waight, Andrew B; Pedersen, Bjorn Panyella; Schlessinger, Avner; Bonomi, Massimiliano; Chau, Bryant H; Roe-Zurz, Zygy; Risenmay, Aaron J; Sali, Andrej; Stroud, Robert M Nature 23685453 2013 May 19
Crystal structure of the integral membrane diacylglycerol kinase. Li, Dianfan; Lyons, Joseph A; Pye, Valerie E; Vogeley, Lutz; Aragao, David; Kenyon, Colin P; Shah, Syed T A; Doherty, Christine; Aherne, Margaret; Caffrey, Martin Nature 23676677 2013 May 23
2D 1H/1H RFDR and NOESY NMR experiments on a membrane-bound antimicrobial peptide under magic angle spinning. Ramamoorthy, Ayyalusamy; Xu, Jiadi The journal of physical chemistry. B 23672643 2013 Jun 6
Trp replacements for tightly interacting Gly-Gly pairs in LacY stabilize an outward-facing conformation. Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 23671103 2013 May 28
Advanced solid-state NMR approaches for structure determination of membrane proteins and amyloid fibrils. Tang, Ming; Comellas, Gemma; Rienstra, Chad M Accounts of chemical research 23659727 2013 Sep 17
Mycobacterial toxin MazF-mt6 inhibits translation through cleavage of 23S rRNA at the ribosomal A site. Schifano, Jason M; Edifor, Regina; Sharp, Jared D; Ouyang, Ming; Konkimalla, Arvind; Husson, Robert N; Woychik, Nancy A Proceedings of the National Academy of Sciences of the United States of America 23650345 2013 May 21
Structure of the human smoothened receptor bound to an antitumour agent. Wang, Chong; Wu, Huixian; Katritch, Vsevolod; Han, Gye Won; Huang, Xi-Ping; Liu, Wei; Siu, Fai Yiu; Roth, Bryan L; Cherezov, Vadim; Stevens, Raymond C Nature 23636324 2013 May 16
Towards protein-crystal centering using second-harmonic generation (SHG) microscopy. Kissick, David J; Dettmar, Christopher M; Becker, Michael; Mulichak, Anne M; Cherezov, Vadim; Ginell, Stephan L; Battaile, Kevin P; Keefe, Lisa J; Fischetti, Robert F; Simpson, Garth J Acta crystallographica. Section D, Biological crystallography 23633594 2013 May
Peptide crystal simulations reveal hidden dynamics. Janowski, Pawel A; Cerutti, David S; Holton, James; Case, David A Journal of the American Chemical Society 23631449 2013 May 29
Conformational Flexibility and Structural Dynamics in GPCR-Mediated G Protein Activation: A Perspective. Preininger, Anita M; Meiler, Jens; Hamm, Heidi E Journal of molecular biology 23602809 2013 Jul 10
Lipid Composition-Dependent Membrane Fragmentation and Pore-Forming Mechanisms of Membrane Disruption by Pexiganan (MSI-78). Lee, Dong-Kuk; Brender, Jeffrey R; Sciacca, Michele F M; Krishnamoorthy, Janarthanan; Yu, Changsu; Ramamoorthy, Ayyalusamy Biochemistry 23590672 2013 Apr 29
Increased expression of the integral membrane proteins EGFR and FGFR3 in anti-apoptotic Chinese hamster ovary cell lines. Ohsfeldt, Erika; Huang, Szu-Han; Baycin-Hizal, Deniz; Kristoffersen, Linda; Le, Thuy-My T; Li, Edwin; Hristova, Kalina; Betenbaugh, Michael J Biotechnology and applied biochemistry 23586824 2012 May-Jun
Crystal structure of a eukaryotic phosphate transporter. Pedersen, Bjorn P; Kumar, Hemant; Waight, Andrew B; Risenmay, Aaron J; Roe-Zurz, Zygy; Chau, Bryant H; Schlessinger, Avner; Bonomi, Massimiliano; Harries, William; Sali, Andrej; Johri, Atul K; Stroud, Robert M Nature 23542591 2013 Apr 25
Evolutionary mix-and-match with MFS transporters. Madej, M Gregor; Dang, Shangyu; Yan, Nieng; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 23530251 2013 Apr 9
Sphingosine-1-phosphate and its receptors: structure, signaling, and influence. Rosen, Hugh; Stevens, Raymond C; Hanson, Michael; Roberts, Edward; Oldstone, Michael B A Annual review of biochemistry 23527695 2013
Solid-state NMR study of a 41 kDa membrane protein complex DsbA/DsbB. Sperling, Lindsay J; Tang, Ming; Berthold, Deborah A; Nesbitt, Anna E; Gennis, Robert B; Rienstra, Chad M The journal of physical chemistry. B 23527473 2013 May 23
Structural features for functional selectivity at serotonin receptors. Wacker, Daniel; Wang, Chong; Katritch, Vsevolod; Han, Gye Won; Huang, Xi-Ping; Vardy, Eyal; McCorvy, John D; Jiang, Yi; Chu, Meihua; Siu, Fai Yiu; Liu, Wei; Xu, H Eric; Cherezov, Vadim; Roth, Bryan L; Stevens, Raymond C Science (New York, N.Y.) 23519215 2013 May 3
Structural basis for molecular recognition at serotonin receptors. Wang, Chong; Jiang, Yi; Ma, Jinming; Wu, Huixian; Wacker, Daniel; Katritch, Vsevolod; Han, Gye Won; Liu, Wei; Huang, Xi-Ping; Vardy, Eyal; McCorvy, John D; Gao, Xiang; Zhou, X Edward; Melcher, Karsten; Zhang, Chenghai; Bai, Fang; Yang, Huaiyu; Yang, Linli Science (New York, N.Y.) 23519210 2013 May 3
Optimizing heterologous protein production in the periplasm of E. coli by regulating gene expression levels. Schlegel, Susan; Rujas, Edurne; Ytterberg, Anders Jimmy; Zubarev, Roman A; Luirink, Joen; de Gier, Jan-Willem Microbial cell factories 23497240 2013
Membrane disordering is not sufficient for membrane permeabilization by islet amyloid polypeptide: studies of IAPP(20-29) fragments. Brender, Jeffrey R; Heyl, Deborah L; Samisetti, Shyamprasad; Kotler, Samuel A; Osborne, Joshua M; Pesaru, Ranadheer R; Ramamoorthy, Ayyalusamy Physical chemistry chemical physics : PCCP 23493863 2013 Jun 21
Steroid-based facial amphiphiles for stabilization and crystallization of membrane proteins. Lee, Sung Chang; Bennett, Brad C; Hong, Wen-Xu; Fu, Yu; Baker, Kent A; Marcoux, Julien; Robinson, Carol V; Ward, Andrew B; Halpert, James R; Stevens, Raymond C; Stout, Charles David; Yeager, Mark J; Zhang, Qinghai Proceedings of the National Academy of Sciences of the United States of America 23479627 2013 Mar 26
Linking receptor activation to changes in Sw I and II of Gýý proteins. Hamm, Heidi E; Kaya, Ali I; Gilbert 3rd, James A; Preininger, Anita M Journal of structural biology 23466875 2013 Mar 4
When detergent meets bilayer: birth and coming of age of lipid bicelles. Durr, Ulrich H N; Soong, Ronald; Ramamoorthy, Ayyalusamy Progress in nuclear magnetic resonance spectroscopy 23465641 2013 Feb
Resolution of oligomeric species during the aggregation of Aýý1-40 using (19)F NMR. Suzuki, Yuta; Brender, Jeffrey R; Soper, Molly T; Krishnamoorthy, Janarthanan; Zhou, Yunlong; Ruotolo, Brandon T; Kotov, Nicholas A; Ramamoorthy, Ayyalusamy; Marsh, E Neil G Biochemistry 23445400 2013 Mar 19
Pulse design for broadband correlation NMR spectroscopy by multi-rotating frames. Coote, Paul; Arthanari, Haribabu; Yu, Tsyr-Yan; Natarajan, Amarnath; Wagner, Gerhard; Khaneja, Navin Journal of biomolecular NMR 23420125 2013 Mar
Structure of the Disulfide Bond Generating Membrane Protein DsbB in the Lipid Bilayer. Tang, Ming; Nesbitt, Anna E; Sperling, Lindsay J; Berthold, Deborah A; Schwieters, Charles D; Gennis, Robert B; Rienstra, Chad M Journal of molecular biology 23416557 2013 May 27
Carbohydrate-containing Triton X-100 analogues for membrane protein solubilization and stabilization. Chae, Pil Seok; Wander, Marc J; Cho, Kyung Ho; Laible, Philip D; Gellman, Samuel H Molecular bioSystems 23377371 2013 Apr 5
Alternate pathways for NADH oxidation in Thermus thermophilus using type 2 NADH dehydrogenases. Venkatakrishnan, Padmaja; Lencina, Andrea M; Schurig-Briccio, Lici A; Gennis, Robert B Biological chemistry 23370906 2013 May
Inward-facing conformation of the zinc transporter YiiP revealed by cryoelectron microscopy. Coudray, Nicolas; Valvo, Salvatore; Hu, Minghui; Lasala, Ralph; Kim, Changki; Vink, Martin; Zhou, Ming; Provasi, Davide; Filizola, Marta; Tao, Juoehi; Fang, Jia; Penczek, Pawel A; Ubarretxena-Belandia, Iban; Stokes, David L Proceedings of the National Academy of Sciences of the United States of America 23341604 2013 Feb 5
Integral membrane proteins and bilayer proteomics. Whitelegge, Julian P Analytical chemistry 23301778 2013 Mar 5
Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins. Hagn, Franz; Etzkorn, Manuel; Raschle, Thomas; Wagner, Gerhard Journal of the American Chemical Society 23294159 2013 Feb 6
Correction to CHOBIMALT: A Cholesterol-Based Detergent. Howell, Stanley C; Fraser, Niall J; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Breyer, Richard M; Sanders, Charles R Biochemistry 23289860 2013 Jan 15
Involvement of distinct arrestin-1 elements in binding to different functional forms of rhodopsin. Zhuang, Tiandi; Chen, Qiuyan; Cho, Min-Kyu; Vishnivetskiy, Sergey A; Iverson, Tina M; Gurevich, Vsevolod V; Sanders, Charles R Proceedings of the National Academy of Sciences of the United States of America 23277586 2013 Jan 15
Microscale thermophoresis quantifies biomolecular interactions under previously challenging conditions. Seidel, Susanne A I; Dijkman, Patricia M; Lea, Wendy A; van den Bogaart, Geert; Jerabek-Willemsen, Moran; Lazic, Ana; Joseph, Jeremiah S; Srinivasan, Prakash; Baaske, Philipp; Simeonov, Anton; Katritch, Ilia; Melo, Fernando A; Ladbury, John E; Schreiber, Methods (San Diego, Calif.) 23270813 2013 Mar
Quantum chemical calculations of amide-15N chemical shift anisotropy tensors for a membrane-bound cytochrome-b5. Pandey, Manoj Kumar; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 23268659 2013 Jan 24
Engineering visual arrestin-1 with special functional characteristics. Vishnivetskiy, Sergey A; Chen, Qiuyan; Palazzo, Maria C; Brooks, Evan K; Altenbach, Christian; Iverson, Tina M; Hubbell, Wayne L; Gurevich, Vsevolod V The Journal of biological chemistry 23250748 2013 Feb 1
The GPCR Network: a large-scale collaboration to determine human GPCR structure and function. Stevens, Raymond C; Cherezov, Vadim; Katritch, Vsevolod; Abagyan, Ruben; Kuhn, Peter; Rosen, Hugh; Wuthrich, Kurt Nature reviews. Drug discovery 23237917 2013 Jan
MetaboID: a graphical user interface package for assignment of 1H NMR spectra of bodyfluids and tissues. MacKinnon, Neil; Somashekar, Bagganahalli S; Tripathi, Pratima; Ge, Wencheng; Rajendiran, Thekkelnaycke M; Chinnaiyan, Arul M; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 23232331 2013 Jan
Natively inhibited Trypanosoma brucei cathepsin B structure determined by using an X-ray laser. Redecke, Lars; Nass, Karol; DePonte, Daniel P; White, Thomas A; Rehders, Dirk; Barty, Anton; Stellato, Francesco; Liang, Mengning; Barends, Thomas R M; Boutet, Sebastien; Williams, Garth J; Messerschmidt, Marc; Seibert, M Marvin; Aquila, Andrew; Arnlund, Science (New York, N.Y.) 23196907 2013 Jan 11
An artificial neural network approach to improving the correlation between protein energetics and the backbone structure. Fawcett, Timothy M; Irausquin, Stephanie J; Simin, Mikhail; Valafar, Homayoun Proteomics 23184572 2013 Jan
Organization of the influenza virus replication machinery. Moeller, Arne; Kirchdoerfer, Robert N; Potter, Clinton S; Carragher, Bridget; Wilson, Ian A Science (New York, N.Y.) 23180774 2012 Dec 21
Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study. Chae, Pil Seok; Rana, Rohini R; Gotfryd, Kamil; Rasmussen, Soren G F; Kruse, Andrew C; Cho, Kyung Ho; Capaldi, Stefano; Carlsson, Emil; Kobilka, Brian; Loland, Claus J; Gether, Ulrik; Banerjee, Surajit; Byrne, Bernadette; Lee, John K; Gellman, Samuel H Chemical communications (Cambridge, England) 23165475 2013 Mar 21
Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans. Thaker, Tarjani M; Tanabe, Mikio; Fowler, Matthew L; Preininger, Anita M; Ingram-Smith, Cheryl; Smith, Kerry S; Iverson, T M Journal of structural biology 23159802 2013 Feb
Dissection of hydrogen bond interaction network around an iron-sulfur cluster by site-specific isotope labeling of hyperthermophilic archaeal Rieske-type ferredoxin. Iwasaki, Toshio; Fukazawa, Risako; Miyajima-Nakano, Yoshiharu; Baldansuren, Amgalanbaatar; Matsushita, Shinichi; Lin, Myat T; Gennis, Robert B; Hasegawa, Kazuya; Kumasaka, Takashi; Dikanov, Sergei A Journal of the American Chemical Society 23145461 2012 Dec 5
High-throughput methods for electron crystallography. Stokes, David L; Ubarretxena-Belandia, Iban; Gonen, Tamir; Engel, Andreas Methods in molecular biology (Clifton, N.J.) 23132066 2013
Modeling, docking, and fitting of atomic structures to 3D maps from cryo-electron microscopy. Allen, Gregory S; Stokes, David L Methods in molecular biology (Clifton, N.J.) 23132064 2013
Three-dimensional localization of the ýý and ýý subunits and of the II-III loop in the skeletal muscle L-type Ca2+ channel. Szpyt, John; Lorenzon, Nancy; Perez, Claudio F; Norris, Ethan; Allen, Paul D; Beam, Kurt G; Samso, Montserrat The Journal of biological chemistry 23118233 2012 Dec 21
Side-chain dynamics reveals transient association of Aýý(1-40) monomers with amyloid fibers. Krishnamoorthy, Janarthanan; Brender, Jeffrey R; Vivekanandan, Subramanian; Jahr, Nicole; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 23116141 2012 Nov 26
Flanking residues are central to DO11.10 T cell hybridoma stimulation by ovalbumin 323-339. Roy, Benjamin M; Zhukov, Dmitriy V; Maynard, Jennifer A PloS one 23110081 2012
Characterization of the Type III sulfide:quinone oxidoreductase from Caldivirga maquilingensis and its membrane binding. Lencina, Andrea M; Ding, Ziqiao; Schurig-Briccio, Lici A; Gennis, Robert B Biochimica et biophysica acta 23103448 2013 Mar
ýý2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements. Horst, Reto; Stanczak, Pawel; Stevens, Raymond C; Wuthrich, Kurt Angewandte Chemie (International ed. in English) 23097212 2013 Jan 2
Crystal structure of a voltage-gated K+ channel pore module in a closed state in lipid membranes. Santos, Jose S; Asmar-Rovira, Guillermo A; Han, Gye Won; Liu, Wei; Syeda, Ruhma; Cherezov, Vadim; Baker, Kent A; Stevens, Raymond C; Montal, Mauricio The Journal of biological chemistry 23095758 2012 Dec 14
The point-spread function of fiber-coupled area detectors. Holton, James M; Nielsen, Chris; Frankel, Kenneth A Journal of synchrotron radiation 23093762 2012 Nov
Structure of the chemokine receptor CXCR1 in phospholipid bilayers. Park, Sang Ho; Das, Bibhuti B; Casagrande, Fabio; Tian, Ye; Nothnagel, Henry J; Chu, Mignon; Kiefer, Hans; Maier, Klaus; De Angelis, Anna A; Marassi, Francesca M; Opella, Stanley J Nature 23086146 2012 Nov 29
Structure of the agonist-bound neurotensin receptor. White, Jim F; Noinaj, Nicholas; Shibata, Yoko; Love, James; Kloss, Brian; Xu, Feng; Gvozdenovic-Jeremic, Jelena; Shah, Priyanka; Shiloach, Joseph; Tate, Christopher G; Grisshammer, Reinhard Nature 23051748 2012 Oct 25
Role of protons in sugar binding to LacY. Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Vazquez-Ibar, Jose Luis; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 23033496 2012 Oct 16
Proton-coupled dynamics in lactose permease. Andersson, Magnus; Bondar, Ana-Nicoleta; Freites, J Alfredo; Tobias, Douglas J; Kaback, H Ronald; White, Stephen H Structure (London, England : 1993) 23000385 2012 Nov 7
Alternative pathways of human islet amyloid polypeptide aggregation distinguished by (19)f nuclear magnetic resonance-detected kinetics of monomer consumption. Suzuki, Yuta; Brender, Jeffrey R; Hartman, Kevin; Ramamoorthy, Ayyalusamy; Marsh, E Neil G Biochemistry 22998665 2012 Oct 16
Solid-state NMR analysis of membrane proteins and protein aggregates by proton detected spectroscopy. Zhou, Donghua H; Nieuwkoop, Andrew J; Berthold, Deborah A; Comellas, Gemma; Sperling, Lindsay J; Tang, Ming; Shah, Gautam J; Brea, Elliott J; Lemkau, Luisel R; Rienstra, Chad M Journal of biomolecular NMR 22986689 2012 Nov
Harvesting and cryo-cooling crystals of membrane proteins grown in lipidic mesophases for structure determination by macromolecular crystallography. Li, Dianfan; Boland, Coilin; Aragao, David; Walsh, Kilian; Caffrey, Martin Journal of visualized experiments : JoVE 22971942 2012
Use of a robot for high-throughput crystallization of membrane proteins in lipidic mesophases. Li, Dianfan; Boland, Coilin; Walsh, Kilian; Caffrey, Martin Journal of visualized experiments : JoVE 22971907 2012
Phosphatidylethanolamine enhances amyloid fiber-dependent membrane fragmentation. Sciacca, Michele F M; Brender, Jeffrey R; Lee, Dong-Kuk; Ramamoorthy, Ayyalusamy Biochemistry 22970795 2012 Oct 2
Two-step mechanism of membrane disruption by Aýý through membrane fragmentation and pore formation. Sciacca, Michele F M; Kotler, Samuel A; Brender, Jeffrey R; Chen, Jennifer; Lee, Dong-kuk; Ramamoorthy, Ayyalusamy Biophysical journal 22947931 2012 Aug 22
Membrane Protein Crystallization in Lipidic Mesophases. Hosting lipid affects on the crystallization and structure of a transmembrane peptide. Hofer, Nicole; Aragao, David; Lyons, Joseph A; Caffrey, Martin Crystal growth & design 22933857 2011 Apr 6
Why GPCRs behave differently in cubic and lamellar lipidic mesophases. Khelashvili, George; Albornoz, Pedro Blecua Carrillo; Johner, Niklaus; Mondal, Sayan; Caffrey, Martin; Weinstein, Harel Journal of the American Chemical Society 22931253 2012 Sep 26
The magic of bicelles lights up membrane protein structure. Durr, Ulrich H N; Gildenberg, Melissa; Ramamoorthy, Ayyalusamy Chemical reviews 22920148 2012 Nov 14
Real-time full-spectral imaging and affinity measurements from 50 microfluidic channels using nanohole surface plasmon resonance. Lee, Si Hoon; Lindquist, Nathan C; Wittenberg, Nathan J; Jordan, Luke R; Oh, Sang-Hyun Lab on a chip 22895607 2012 Oct 21
Micro-coil NMR to monitor optimization of the reconstitution conditions for the integral membrane protein OmpW in detergent micelles. Stanczak, Pawel; Zhang, Qinghai; Horst, Reto; Serrano, Pedro; Wuthrich, Kurt Journal of biomolecular NMR 22890565 2012 Oct
Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes? McHenry, Austin J; Sciacca, Michele F M; Brender, Jeffrey R; Ramamoorthy, Ayyalusamy Biochimica et biophysica acta 22885355 2012 Dec
Optimizing membrane protein overexpression in the Escherichia coli strain Lemo21(DE3). Schlegel, Susan; Lofblom, John; Lee, Chiara; Hjelm, Anna; Klepsch, Mirjam; Strous, Marc; Drew, David; Slotboom, Dirk Jan; de Gier, Jan-Willem Journal of molecular biology 22858868 2012 Nov 2
Aquaporin 4-specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize Clostridium ABC transporter. Varrin-Doyer, Michel; Spencer, Collin M; Schulze-Topphoff, Ulf; Nelson, Patricia A; Stroud, Robert M; Cree, Bruce A C; Zamvil, Scott S Annals of neurology 22807325 2012 Jul
Structural basis for allosteric regulation of GPCRs by sodium ions. Liu, Wei; Chun, Eugene; Thompson, Aaron A; Chubukov, Pavel; Xu, Fei; Katritch, Vsevolod; Han, Gye Won; Roth, Christopher B; Heitman, Laura H; IJzerman, Adriaan P; Cherezov, Vadim; Stevens, Raymond C Science (New York, N.Y.) 22798613 2012 Jul 13
Membrane protein structure determination using crystallography and lipidic mesophases: recent advances and successes. Caffrey, Martin; Li, Dianfan; Dukkipati, Abhiram Biochemistry 22783824 2012 Aug 14
Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies. Tao, Houchao; Fu, Yu; Thompson, Aaron; Lee, Sung Chang; Mahoney, Nicholas; Stevens, Raymond C; Zhang, Qinghai Langmuir : the ACS journal of surfaces and colloids 22780816 2012 Jul 31
Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability. Miller, Maria A; Khan, Tarik A; Kaczorowski, Kevin J; Wilson, Brian K; Dinin, Aileen K; Borwankar, Ameya U; Rodrigues, Miguel A; Truskett, Thomas M; Johnston, Keith P; Maynard, Jennifer A Journal of pharmaceutical sciences 22777686 2012 Oct
Structural insights into electron transfer in caa3-type cytochrome oxidase. Lyons, Joseph A; Aragao, David; Slattery, Orla; Pisliakov, Andrei V; Soulimane, Tewfik; Caffrey, Martin Nature 22763450 2012 Jul 26
Delineating metabolic signatures of head and neck squamous cell carcinoma: phospholipase A2, a potential therapeutic target. Tripathi, Pratima; Kamarajan, Pachiyappan; Somashekar, Bagganahalli S; MacKinnon, Neil; Chinnaiyan, Arul M; Kapila, Yvonne L; Rajendiran, Thekkelnaycke M; Ramamoorthy, Ayyalusamy The international journal of biochemistry & cell biology 22743333 2012 Nov
A new class of amphiphiles bearing rigid hydrophobic groups for solubilization and stabilization of membrane proteins. Chae, Pil Seok; Rasmussen, Soren G F; Rana, Rohini R; Gotfryd, Kamil; Kruse, Andrew C; Manglik, Aashish; Cho, Kyung Ho; Nurva, Shailika; Gether, Ulrik; Guan, Lan; Loland, Claus J; Byrne, Bernadette; Kobilka, Brian K; Gellman, Samuel H Chemistry (Weinheim an der Bergstrasse, Germany) 22730191 2012 Jul 27
Coherent averaging in the frequency domain. Khitrin, A K; Xu, Jiadi; Ramamoorthy, Ayyalusamy The Journal of chemical physics 22697555 2012 Jun 7
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors. Chun, Eugene; Thompson, Aaron A; Liu, Wei; Roth, Christopher B; Griffith, Mark T; Katritch, Vsevolod; Kunken, Joshua; Xu, Fei; Cherezov, Vadim; Hanson, Michael A; Stevens, Raymond C Structure (London, England : 1993) 22681902 2012 Jun 6
Crystal structures of the outer membrane domain of intimin and invasin from enterohemorrhagic E. coli and enteropathogenic Y. pseudotuberculosis. Fairman, James W; Dautin, Nathalie; Wojtowicz, Damian; Liu, Wei; Noinaj, Nicholas; Barnard, Travis J; Udho, Eshwar; Przytycka, Teresa M; Cherezov, Vadim; Buchanan, Susan K Structure (London, England : 1993) 22658748 2012 Jul 3
High-resolution protein structure determination by serial femtosecond crystallography. Boutet, Sebastien; Lomb, Lukas; Williams, Garth J; Barends, Thomas R M; Aquila, Andrew; Doak, R Bruce; Weierstall, Uwe; DePonte, Daniel P; Steinbrener, Jan; Shoeman, Robert L; Messerschmidt, Marc; Barty, Anton; White, Thomas A; Kassemeyer, Stephan; Kirian Science (New York, N.Y.) 22653729 2012 Jul 20
The Skp chaperone helps fold soluble proteins in vitro by inhibiting aggregation. Entzminger, Kevin C; Chang, Christine; Myhre, Ryan O; McCallum, Katie C; Maynard, Jennifer A Biochemistry 22650963 2012 Jun 19
Characterization of the PIB-Type ATPases present in Thermus thermophilus. Schurig-Briccio, Lici A; Gennis, Robert B Journal of bacteriology 22636781 2012 Aug
Determination of 15N chemical shift anisotropy from a membrane-bound protein by NMR spectroscopy. Pandey, Manoj Kumar; Vivekanandan, Subramanian; Ahuja, Shivani; Pichumani, Kumar; Im, Sang-Choul; Waskell, Lucy; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 22620865 2012 Jun 21
Variable reference alignment: an improved peak alignment protocol for NMR spectral data with large intersample variation. MacKinnon, Neil; Ge, Wencheng; Khan, Amjad P; Somashekar, Bagganahalli S; Tripathi, Pratima; Siddiqui, Javed; Wei, John T; Chinnaiyan, Arul M; Rajendiran, Thekkelnaycke M; Ramamoorthy, Ayyalusamy Analytical chemistry 22616856 2012 Jun 19
Facile backbone structure determination of human membrane proteins by NMR spectroscopy. Klammt, Christian; Maslennikov, Innokentiy; Bayrhuber, Monika; Eichmann, Cedric; Vajpai, Navratna; Chiu, Ellis Jeremy Chua; Blain, Katherine Y; Esquivies, Luis; Kwon, June Hyun Jung; Balana, Bartosz; Pieper, Ursula; Sali, Andrej; Slesinger, Paul A; Kwiatk Nature methods 22609626 2012 Aug
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic. Thompson, Aaron A; Liu, Wei; Chun, Eugene; Katritch, Vsevolod; Wu, Huixian; Vardy, Eyal; Huang, Xi-Ping; Trapella, Claudio; Guerrini, Remo; Calo, Girolamo; Roth, Bryan L; Cherezov, Vadim; Stevens, Raymond C Nature 22596163 2012 May 17
Membrane protein structure determination by electron crystallography. Ubarretxena-Belandia, Iban; Stokes, David L Current opinion in structural biology 22572457 2012 Aug
Product-controlled steady-state kinetics between cytochrome aa(3) from Rhodobacter sphaeroides and equine ferrocytochrome c analyzed by a novel spectrophotometric approach. Lin, Myat T; Gennis, Robert B Biochimica et biophysica acta 22516686 2012 Oct
Fabs enable single particle cryoEM studies of small proteins. Wu, Shenping; Avila-Sakar, Agustin; Kim, JungMin; Booth, David S; Greenberg, Charles H; Rossi, Andrea; Liao, Maofu; Li, Xueming; Alian, Akram; Griner, Sarah L; Juge, Narinobu; Yu, Yadong; Mergel, Claudia M; Chaparro-Riggers, Javier; Strop, Pavel; Tampe, R Structure (London, England : 1993) 22483106 2012 Apr 4
Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals. Gonzalez-Gutierrez, Giovanni; Lukk, Tiit; Agarwal, Vinayak; Papke, David; Nair, Satish K; Grosman, Claudio Proceedings of the National Academy of Sciences of the United States of America 22474383 2012 Apr 17
Racemic protein crystallography. Yeates, Todd O; Kent, Stephen B H Annual review of biophysics 22443988 2012
Structure of the human ýý-opioid receptor in complex with JDTic. Wu, Huixian; Wacker, Daniel; Mileni, Mauro; Katritch, Vsevolod; Han, Gye Won; Vardy, Eyal; Liu, Wei; Thompson, Aaron A; Huang, Xi-Ping; Carroll, F Ivy; Mascarella, S Wayne; Westkaemper, Richard B; Mosier, Philip D; Roth, Bryan L; Cherezov, Vadim; Stevens, Nature 22437504 2012 May 17
Lipid dynamics and protein-lipid interactions in 2D crystals formed with the ýý-barrel integral membrane protein VDAC1. Eddy, Matthew T; Ong, Ta-Chung; Clark, Lindsay; Teijido, Oscar; van der Wel, Patrick C A; Garces, Robert; Wagner, Gerhard; Rostovtseva, Tatiana K; Griffin, Robert G Journal of the American Chemical Society 22435461 2012 Apr 11
Engineering genes for predictable protein expression. Gustafsson, Claes; Minshull, Jeremy; Govindarajan, Sridhar; Ness, Jon; Villalobos, Alan; Welch, Mark Protein expression and purification 22425659 2012 May
Tissue factor/factor VIIa complex: role of the membrane surface. Morrissey, James H; Tajkhorshid, Emad; Sligar, Stephen G; Rienstra, Chad M Thrombosis research 22417943 2012 May
Role of Gly117 in the cation/melibiose symport of MelB of Salmonella typhimurium. Guan, Lan; Jakkula, S Vivek; Hodkoff, Alexey A; Su, Yue Biochemistry 22413840 2012 Apr 3
Evidence for an intermediate conformational state of LacY. Jiang, Xiaoxu; Guan, Lan; Zhou, Yonggang; Hong, Wen-Xu; Zhang, Qinghai; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 22355148 2012 Mar 20
Crystal structure of a lipid G protein-coupled receptor. Hanson, Michael A; Roth, Christopher B; Jo, Euijung; Griffith, Mark T; Scott, Fiona L; Reinhart, Greg; Desale, Hans; Clemons, Bryan; Cahalan, Stuart M; Schuerer, Stephan C; Sanna, M Germana; Han, Gye Won; Kuhn, Peter; Rosen, Hugh; Stevens, Raymond C Science (New York, N.Y.) 22344443 2012 Feb 17
Translational diffusion measurements by microcoil NMR in aqueous solutions of the Fos-10 detergent-solubilized membrane protein OmpX. Horst, Reto; Stanczak, Pawel; Serrano, Pedro; Wuthrich, Kurt The journal of physical chemistry. B 22335573 2012 Jun 14
Time-resolved protein nanocrystallography using an X-ray free-electron laser. Aquila, Andrew; Hunter, Mark S; Doak, R Bruce; Kirian, Richard A; Fromme, Petra; White, Thomas A; Andreasson, Jakob; Arnlund, David; Bajt, Sasa; Barends, Thomas R M; Barthelmess, Miriam; Bogan, Michael J; Bostedt, Christoph; Bottin, Herve; Bozek, John D; Optics express 22330507 2012 Jan 30
Overexpressing human membrane proteins in stably transfected and clonal human embryonic kidney 293S cells. Chaudhary, Sarika; Pak, John E; Gruswitz, Franz; Sharma, Vinay; Stroud, Robert M Nature protocols 22322218 2012 Mar
Heparan sulfate chains of syndecan-1 regulate ectodomain shedding. Ramani, Vishnu C; Pruett, Pamela S; Thompson, Camilla A; DeLucas, Lawrence D; Sanderson, Ralph D The Journal of biological chemistry 22298773 2012 Mar 23
Two tyrosyl radicals stabilize high oxidation states in cytochrome C oxidase for efficient energy conservation and proton translocation. Yu, Michelle A; Egawa, Tsuyoshi; Shinzawa-Itoh, Kyoko; Yoshikawa, Shinya; Guallar, Victor; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary J Journal of the American Chemical Society 22296274 2012 Mar 14
In vivo protein crystallization opens new routes in structural biology. Koopmann, Rudolf; Cupelli, Karolina; Redecke, Lars; Nass, Karol; Deponte, Daniel P; White, Thomas A; Stellato, Francesco; Rehders, Dirk; Liang, Mengning; Andreasson, Jakob; Aquila, Andrew; Bajt, Sasa; Barthelmess, Miriam; Barty, Anton; Bogan, Michael J; B Nature methods 22286384 2012 Mar
Lipidic phase membrane protein serial femtosecond crystallography. Johansson, Linda C; Arnlund, David; White, Thomas A; Katona, Gergely; Deponte, Daniel P; Weierstall, Uwe; Doak, R Bruce; Shoeman, Robert L; Lomb, Lukas; Malmerberg, Erik; Davidsson, Jan; Nass, Karol; Liang, Mengning; Andreasson, Jakob; Aquila, Andrew; Baj Nature methods 22286383 2012 Mar
Biased signaling pathways in ýý2-adrenergic receptor characterized by 19F-NMR. Liu, Jeffrey J; Horst, Reto; Katritch, Vsevolod; Stevens, Raymond C; Wuthrich, Kurt Science (New York, N.Y.) 22267580 2012 Mar 2
Nucleotide-dependent conformational changes in the N-Ethylmaleimide Sensitive Factor (NSF) and their potential role in SNARE complex disassembly. Moeller, Arne; Zhao, Chunxia; Fried, Michael G; Wilson-Kubalek, Elizabeth M; Carragher, Bridget; Whiteheart, Sidney W Journal of structural biology 22245547 2012 Feb
Nanohole-based surface plasmon resonance instruments with improved spectral resolution quantify a broad range of antibody-ligand binding kinetics. Im, Hyungsoon; Sutherland, Jamie N; Maynard, Jennifer A; Oh, Sang-Hyun Analytical chemistry 22235895 2012 Feb 21
Structure determination of a membrane protein in proteoliposomes. Das, Bibhuti B; Nothnagel, Henry J; Lu, George J; Son, Woo Sung; Tian, Ye; Marassi, Francesca M; Opella, Stanley J Journal of the American Chemical Society 22217388 2012 Feb 1
Biogenesis of inner membrane proteins in Escherichia coli. Luirink, Joen; Yu, Zhong; Wagner, Samuel; de Gier, Jan-Willem Biochimica et biophysica acta 22201544 2012 Jun
Toward structure determination using membrane-protein nanocrystals and microcrystals. Hunter, Mark S; Fromme, Petra Methods (San Diego, Calif.) 22197730 2011 Dec
VITAL NMR: using chemical shift derived secondary structure information for a limited set of amino acids to assess homology model accuracy. Brothers, Michael C; Nesbitt, Anna E; Hallock, Michael J; Rupasinghe, Sanjeewa G; Tang, Ming; Harris, Jason; Baudry, Jerome; Schuler, Mary A; Rienstra, Chad M Journal of biomolecular NMR 22183804 2012 Jan
Convergent chemical synthesis of [lysine(24,38,83)] human erythropoietin. Liu, Suhuai; Pentelute, Brad L; Kent, Stephen B H Angewandte Chemie (International ed. in English) 22180156 2012 Jan 23
Diverging mechanisms of activation of chemokine receptors revealed by novel chemokine agonists. Sarmiento, Jose; Shumate, Christie; Suetomi, Katsutoshi; Ravindran, Aishwarya; Villegas, Leon; Rajarathnam, Krishna; Navarro, Javier PloS one 22174759 2011
Directed evolution of mammalian anti-apoptosis proteins by somatic hypermutation. Majors, Brian S; Chiang, Gisela G; Pederson, Nels E; Betenbaugh, Michael J Protein engineering, design & selection : PEDS 22160868 2012 Jan
Restriction enzyme-free construction of random gene mutagenesis libraries in Escherichia coli. Pai, Jen C; Entzminger, Kevin C; Maynard, Jennifer A Analytical biochemistry 22155067 2012 Feb 15
Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. McClure, Michelle; DeLucas, Lawrence J; Wilson, Landon; Ray, Marjorie; Rowe, Steven M; Wu, Xiaoyun; Dai, Qun; Hong, Jeong S; Sorscher, Eric J; Kappes, John C; Barnes, Stephen Protein engineering, design & selection : PEDS 22119790 2012 Jan
Solution NMR spectroscopic characterization of human VDAC-2 in detergent micelles and lipid bilayer nanodiscs. Yu, Tsyr-Yan; Raschle, Thomas; Hiller, Sebastian; Wagner, Gerhard Biochimica et biophysica acta 22119777 2012 Jun
Sugar recognition by CscB and LacY. Sugihara, Junichi; Smirnova, Irina; Kasho, Vladimir; Kaback, H Ronald Biochemistry 22106930 2011 Dec 27
Screening of protein crystallization trials by second order nonlinear optical imaging of chiral crystals (SONICC). Haupert, Levi M; Simpson, Garth J Methods (San Diego, Calif.) 22101350 2011 Dec
An active photoreceptor intermediate revealed by in situ photoirradiated solid-state NMR spectroscopy. Tomonaga, Yuya; Hidaka, Tetsurou; Kawamura, Izuru; Nishio, Takudo; Ohsawa, Kazuhiro; Okitsu, Takashi; Wada, Akimori; Sudo, Yuki; Kamo, Naoki; Ramamoorthy, Ayyalusamy; Naito, Akira Biophysical journal 22098758 2011 Nov 16
Membrane proteins in four acts: function precedes structure determination. Cramer, W A; Zakharov, S D; Saif Hasan, S; Zhang, H; Baniulis, D; Zhalnina, M V; Soriano, G M; Sharma, O; Rochet, J C; Ryan, C; Whitelegge, J; Kurisu, G; Yamashita, E Methods (San Diego, Calif.) 22079407 2011 Dec
Allosteric mechanisms of G protein-Coupled Receptor signaling: a structural perspective. Thaker, Tarjani M; Kaya, Ali I; Preininger, Anita M; Hamm, Heidi E; Iverson, T M Methods in molecular biology (Clifton, N.J.) 22052489 2012
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles. Thompson, Aaron A; Liu, Jeffrey J; Chun, Eugene; Wacker, Daniel; Wu, Huixian; Cherezov, Vadim; Stevens, Raymond C Methods (San Diego, Calif.) 22041719 2011 Dec
Diversity and modularity of G protein-coupled receptor structures. Katritch, Vsevolod; Cherezov, Vadim; Stevens, Raymond C Trends in pharmacological sciences 22032986 2012 Jan
Interactions of interleukin-8 with the human chemokine receptor CXCR1 in phospholipid bilayers by NMR spectroscopy. Park, Sang Ho; Casagrande, Fabio; Cho, Leah; Albrecht, Lauren; Opella, Stanley J Journal of molecular biology 22019593 2011 Nov 25
Lactose permease and the alternating access mechanism. Smirnova, Irina; Kasho, Vladimir; Kaback, H Ronald Biochemistry 21995338 2011 Nov 15
Escherichia coli peptide binding protein OppA has a preference for positively charged peptides. Klepsch, M M; Kovermann, M; Low, C; Balbach, J; Permentier, H P; Fusetti, F; de Gier, J W; Slotboom, D J; Berntsson, R P-A Journal of molecular biology 21983341 2011 Nov 18
Conservation of lipid functions in cytochrome bc complexes. Hasan, S Saif; Yamashita, Eiki; Ryan, Christopher M; Whitelegge, Julian P; Cramer, William A Journal of molecular biology 21978667 2011 Nov 18
Ultrahigh resolution protein structures using NMR chemical shift tensors. Wylie, Benjamin J; Sperling, Lindsay J; Nieuwkoop, Andrew J; Franks, W Trent; Oldfield, Eric; Rienstra, Chad M Proceedings of the National Academy of Sciences of the United States of America 21969532 2011 Oct 11
A helical processing pipeline for EM structure determination of membrane proteins. Fisher, Lauren S; Ward, Andrew; Milligan, Ronald A; Unwin, Nigel; Potter, Clinton S; Carragher, Bridget Methods (San Diego, Calif.) 21964395 2011 Dec
Structure determination of membrane proteins in five easy pieces. Marassi, Francesca M; Das, Bibhuti B; Lu, George J; Nothnagel, Henry J; Park, Sang Ho; Son, Woo Sung; Tian, Ye; Opella, Stanley J Methods (San Diego, Calif.) 21964394 2011 Dec
A pseudoatomic model of the dynamin polymer identifies a hydrolysis-dependent powerstroke. Chappie, Joshua S; Mears, Jason A; Fang, Shunming; Leonard, Marilyn; Schmid, Sandra L; Milligan, Ronald A; Hinshaw, Jenny E; Dyda, Fred Cell 21962517 2011 Sep 30
New amphiphiles for membrane protein structural biology. Zhang, Qinghai; Tao, Houchao; Hong, Wen-Xu Methods (San Diego, Calif.) 21958988 2011 Dec
Rapid identification of recombinant Fabs that bind to membrane proteins. Kim, Jungmin; Stroud, Robert M; Craik, Charles S Methods (San Diego, Calif.) 21958987 2011 Dec
Membrane interaction of Pasteurella multocida toxin involves sphingomyelin. Brothers, Michael C; Ho, Mengfei; Maharjan, Ram; Clemons, Nathan C; Bannai, Yuka; Waites, Mark A; Faulkner, Melinda J; Kuhlenschmidt, Theresa B; Kuhlenschmidt, Mark S; Blanke, Steven R; Rienstra, Chad M; Wilson, Brenda A The FEBS journal 21951695 2011 Dec
Investigating the intermediates in the reaction of ribonucleoside triphosphate reductase from Lactobacillus leichmannii: An application of HF EPR-RFQ technology. Manzerova, Julia; Krymov, Vladimir; Gerfen, Gary J Journal of magnetic resonance (San Diego, Calif. : 1997) 21944735 2011 Dec
Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective. Brender, Jeffrey R; Salamekh, Samer; Ramamoorthy, Ayyalusamy Accounts of chemical research 21942864 2011 Sep 25
Fast NMR data acquisition from bicelles containing a membrane-associated peptide at natural-abundance. Yamamoto, Kazutoshi; Vivekanandan, Subramanian; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 21939237 2011 Nov 3
High-resolution membrane protein structure by joint calculations with solid-state NMR and X-ray experimental data. Tang, Ming; Sperling, Lindsay J; Berthold, Deborah A; Schwieters, Charles D; Nesbitt, Anna E; Nieuwkoop, Andrew J; Gennis, Robert B; Rienstra, Chad M Journal of biomolecular NMR 21938394 2011 Nov
Initial evaluation of a direct detection device detector for single particle cryo-electron microscopy. Milazzo, Anna-Clare; Cheng, Anchi; Moeller, Arne; Lyumkis, Dmitry; Jacovetty, Erica; Polukas, James; Ellisman, Mark H; Xuong, Nguyen-Huu; Carragher, Bridget; Potter, Clinton S Journal of structural biology 21933715 2011 Dec
Efficient expression screening of human membrane proteins in transiently transfected Human Embryonic Kidney 293S cells. Chaudhary, Sarika; Pak, John E; Pedersen, Bjorn P; Bang, Lois J; Zhang, Liye B; Ngaw, Samantha M M; Green, Raissa G; Sharma, Vinay; Stroud, Robert M Methods (San Diego, Calif.) 21925269 2011 Dec
A rapid and robust method for selective isotope labeling of proteins. Lin, Myat T; Sperling, Lindsay J; Frericks Schmidt, Heather L; Tang, Ming; Samoilova, Rimma I; Kumasaka, Takashi; Iwasaki, Toshio; Dikanov, Sergei A; Rienstra, Chad M; Gennis, Robert B Methods (San Diego, Calif.) 21925267 2011 Dec
Translational diffusion of macromolecular assemblies measured using transverse-relaxation-optimized pulsed field gradient NMR. Horst, Reto; Horwich, Arthur L; Wuthrich, Kurt Journal of the American Chemical Society 21919531 2011 Oct 19
Accessing protein conformational ensembles using room-temperature X-ray crystallography. Fraser, James S; van den Bedem, Henry; Samelson, Avi J; Lang, P Therese; Holton, James M; Echols, Nathaniel; Alber, Tom Proceedings of the National Academy of Sciences of the United States of America 21918110 2011 Sep 27
Monoolein lipid phases as incorporation and enrichment materials for membrane protein crystallization. Wallace, Ellen; Dranow, David; Laible, Philip D; Christensen, Jeff; Nollert, Peter PloS one 21909395 2011
Characterization of lipid matrices for membrane protein crystallization by high-throughput small angle X-ray scattering. Joseph, Jeremiah S; Liu, Wei; Kunken, Joshua; Weiss, Thomas M; Tsuruta, Hiro; Cherezov, Vadim Methods (San Diego, Calif.) 21903166 2011 Dec
Manipulating the genetic code for membrane protein production: what have we learnt so far? Norholm, Morten H H; Light, Sara; Virkki, Minttu T I; Elofsson, Arne; von Heijne, Gunnar; Daley, Daniel O Biochimica et biophysica acta 21884679 2012 Apr
Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl)pyridine: insight into inhibitor binding and rearrangement of active site side chains. Shah, Manish B; Pascual, Jaime; Zhang, Qinghai; Stout, C David; Halpert, James R Molecular pharmacology 21875942 2011 Dec
Crystallization chaperone strategies for membrane proteins. Lieberman, Raquel L; Culver, Jeffrey A; Entzminger, Kevin C; Pai, Jennifer C; Maynard, Jennifer A Methods (San Diego, Calif.) 21854852 2011 Dec
Solid-State NMR of a Large Membrane Protein by Paramagnetic Relaxation Enhancement. Tang, Ming; Berthold, Deborah A; Rienstra, Chad M The journal of physical chemistry letters 21841965 2011 Jul 21
Cross-correlations between low-ýý nuclei in solids via a common dipolar bath. Khitrin, Aanatoly K; Xu, Jiadi; Ramamoorthy, Ayyalusamy Journal of magnetic resonance (San Diego, Calif. : 1997) 21820340 2011 Sep
High resolution structure of the ba3 cytochrome c oxidase from Thermus thermophilus in a lipidic environment. Tiefenbrunn, Theresa; Liu, Wei; Chen, Ying; Katritch, Vsevolod; Stout, C David; Fee, James A; Cherezov, Vadim PloS one 21814577 2011
A reference map of the membrane proteome of Enterococcus faecalis. Maddalo, Gianluca; Chovanec, Peter; Stenberg-Bruzell, Filippa; Nielsen, Hailyn V; Jensen-Seaman, Michael I; Ilag, Leopold L; Kline, Kimberly A; Daley, Daniel O Proteomics 21800426 2011 Oct
Nanoscale studies of protein-membrane interactions in blood clotting. Morrissey, J H; Tajkhorshid, E; Rienstra, C M Journal of thrombosis and haemostasis : JTH 21781251 2011 Jul
Lipidic cubic phase technologies for membrane protein structural studies. Cherezov, Vadim Current opinion in structural biology 21775127 2011 Aug
In situ structural characterization of a recombinant protein in native Escherichia coli membranes with solid-state magic-angle-spinning NMR. Fu, Riqiang; Wang, Xingsheng; Li, Conggang; Santiago-Miranda, Adriana N; Pielak, Gary J; Tian, Fang Journal of the American Chemical Society 21774553 2011 Aug 17
Crystal structure of the ýý2 adrenergic receptor-Gs protein complex. Rasmussen, Soren G F; DeVree, Brian T; Zou, Yaozhong; Kruse, Andrew C; Chung, Ka Young; Kobilka, Tong Sun; Thian, Foon Sun; Chae, Pil Seok; Pardon, Els; Calinski, Diane; Mathiesen, Jesper M; Shah, Syed T A; Lyons, Joseph A; Caffrey, Martin; Gellman, Samue Nature 21772288 2011 Sep 29
The conformation of bacteriorhodopsin loops in purple membranes resolved by solid-state MAS NMR spectroscopy. Higman, Victoria A; Varga, Krisztina; Aslimovska, Lubica; Judge, Peter J; Sperling, Lindsay J; Rienstra, Chad M; Watts, Anthony Angewandte Chemie (International ed. in English) 21770003 2011 Aug 29
Femtosecond nanocrystallography using X-ray lasers for membrane protein structure determination. Fromme, Petra; Spence, John C H Current opinion in structural biology 21752635 2011 Aug
Voltage-gated sodium channel (NaV) protein dissection creates a set of functional pore-only proteins. Shaya, David; Kreir, Mohamed; Robbins, Rebecca A; Wong, Stephanie; Hammon, Justus; Bruggemann, Andrea; Minor Jr, Daniel L Proceedings of the National Academy of Sciences of the United States of America 21746903 2011 Jul 26
Total chemical synthesis of biologically active vascular endothelial growth factor. Mandal, Kalyaneswar; Kent, Stephen B H Angewandte Chemie (International ed. in English) 21744452 2011 Aug 22
Crystallizing Membrane Proteins in Lipidic Mesophases. A Host Lipid Screen. Li, Dianfan; Lee, Jean; Caffrey, Martin Crystal growth & design 21743796 2011
An early event in the transport mechanism of LacY protein: interaction between helices V and I. Zhou, Yonggang; Madej, M Gregor; Guan, Lan; Nie, Yiling; Kaback, H Ronald The Journal of biological chemistry 21730060 2011 Sep 2
Structural and functional basis for RNA cleavage by Ire1. Korennykh, Alexei V; Korostelev, Andrei A; Egea, Pascal F; Finer-Moore, Janet; Stroud, Robert M; Zhang, Chao; Shokat, Kevan M; Walter, Peter BMC biology 21729333 2011
Radical formation in cytochrome c oxidase. Yu, Michelle A; Egawa, Tsuyoshi; Shinzawa-Itoh, Kyoko; Yoshikawa, Shinya; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary J Biochimica et biophysica acta 21718686 2011 Oct
Structure of the human histamine H1 receptor complex with doxepin. Shimamura, Tatsuro; Shiroishi, Mitsunori; Weyand, Simone; Tsujimoto, Hirokazu; Winter, Graeme; Katritch, Vsevolod; Abagyan, Ruben; Cherezov, Vadim; Liu, Wei; Han, Gye Won; Kobayashi, Takuya; Stevens, Raymond C; Iwata, So Nature 21697825 2011 Jul 7
Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments. Hong, Heedeok; Bowie, James U Journal of the American Chemical Society 21682279 2011 Jul 27
Development of an Automated High Throughput LCP-FRAP Assay to Guide Membrane Protein Crystallization in Lipid Mesophases. Xu, Fei; Liu, Wei; Hanson, Michael A; Stevens, Raymond C; Cherezov, Vadim Crystal growth & design 21660116 2011 Apr 6
The crystal structure of the ýý-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function. Miller, Meghan T; Mileni, Mauro; Comoletti, Davide; Stevens, Raymond C; Harel, Michal; Taylor, Palmer Structure (London, England : 1993) 21620717 2011 Jun 8
Crystallizing membrane proteins for structure-function studies using lipidic mesophases. Caffrey, Martin Biochemical Society transactions 21599641 2011 Jun
Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Chaptal, Vincent; Kwon, Seunghyug; Sawaya, Michael R; Guan, Lan; Kaback, H Ronald; Abramson, Jeff Proceedings of the National Academy of Sciences of the United States of America 21593407 2011 Jun 7
Molecular determinants of phospholipid synergy in blood clotting. Tavoosi, Narjes; Davis-Harrison, Rebecca L; Pogorelov, Taras V; Ohkubo, Y Zenmei; Arcario, Mark J; Clay, Mary C; Rienstra, Chad M; Tajkhorshid, Emad; Morrissey, James H The Journal of biological chemistry 21561861 2011 Jul 1
Lipid cubic phase as a membrane mimetic for integral membrane protein enzymes. Li, Dianfan; Caffrey, Martin Proceedings of the National Academy of Sciences of the United States of America 21555546 2011 May 24
1H assisted 13C/15N heteronuclear correlation spectroscopy in oriented sample solid-state NMR of single crystal and magnetically aligned samples. Lin, Eugene C; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 21543244 2011 Jul
The variable detergent sensitivity of proteases that are utilized for recombinant protein affinity tag removal. Vergis, James M; Wiener, Michael C Protein expression and purification 21539919 2011 Aug
Structural analysis of mammalian cytochrome P450 2B4 covalently bound to the mechanism-based inactivator tert-butylphenylacetylene: insight into partial enzymatic activity. Gay, Sean C; Zhang, Haoming; Wilderman, P Ross; Roberts, Arthur G; Liu, Tong; Li, Sheng; Lin, Hsia-Lien; Zhang, Qinghai; Woods Jr, Virgil L; Stout, C David; Hollenberg, Paul F; Halpert, James R Biochemistry 21510666 2011 Jun 7
Characterization of the consequences of YidC depletion on the inner membrane proteome of E. coli using 2D blue native/SDS-PAGE. Wickstrom, David; Wagner, Samuel; Simonsson, Per; Pop, Ovidiu; Baars, Louise; Ytterberg, A Jimmy; van Wijk, Klaas J; Luirink, Joen; de Gier, Jan-Willem L Journal of molecular biology 21497606 2011 Jun 3
Crystallization of membrane proteins in lipidic mesophases. Liu, Wei; Cherezov, Vadim Journal of visualized experiments : JoVE 21490572 2011
Second-order nonlinear optical imaging of chiral crystals. Kissick, David J; Wanapun, Debbie; Simpson, Garth J Annual review of analytical chemistry (Palo Alto, Calif.) 21469954 2011
A proton spin diffusion based solid-state NMR approach for structural studies on aligned samples. Xu, Jiadi; Smith, Pieter E S; Soong, Ronald; Ramamoorthy, Ayyalusamy The journal of physical chemistry. B 21466219 2011 Apr 28
The metabolic bioactivation of caffeic acid phenethyl ester (CAPE) mediated by tyrosinase selectively inhibits glutathione S-transferase. Kudugunti, Shashi K; Thorsheim, Helen; Yousef, Mohammad S; Guan, Lan; Moridani, Majid Y Chemico-biological interactions 21458432 2011 Jul 15
Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria. Xu, Yongbin; Lee, Minho; Moeller, Arne; Song, Saemee; Yoon, Bo-Young; Kim, Hong-Man; Jun, So-Young; Lee, Kangseok; Ha, Nam-Chul The Journal of biological chemistry 21454662 2011 May 20
Identification of chromatophore membrane protein complexes formed under different nitrogen availability conditions in Rhodospirillum rubrum. Selao, Tiago Toscano; Branca, Rui; Chae, Pil Seok; Lehtio, Janne; Gellman, Samuel H; Rasmussen, Soren G F; Nordlund, Stefan; Noren, Agneta Journal of proteome research 21443180 2011 Jun 3
Structural comparisons of arachidonic acid-induced radicals formed by prostaglandin H synthase-1 and -2. Tsai, Ah-lim; Wu, Gang; Rogge, Corina E; Lu, Jian-Ming; Peng, Sheng; van der Donk, Wilfred A; Palmer, Graham; Gerfen, Gary J; Kulmacz, Richard J Journal of inorganic biochemistry 21421123 2011 Mar
Label-free quantification of membrane-ligand interactions using backscattering interferometry. Baksh, Michael M; Kussrow, Amanda K; Mileni, Mauro; Finn, M G; Bornhop, Darryl J Nature biotechnology 21399645 2011 Apr
Structure of an agonist-bound human A2A adenosine receptor. Xu, Fei; Wu, Huixian; Katritch, Vsevolod; Han, Gye Won; Jacobson, Kenneth A; Gao, Zhan-Guo; Cherezov, Vadim; Stevens, Raymond C Science (New York, N.Y.) 21393508 2011 Apr 15
Coupling efficiency of rhodopsin and transducin in bicelles. Kaya, Ali I; Thaker, Tarjani M; Preininger, Anita M; Iverson, T M; Hamm, Heidi E Biochemistry 21375271 2011 Apr 19
Solid-state NMR study of the charge-transfer complex between ubiquinone-8 and disulfide bond generating membrane protein DsbB. Tang, Ming; Sperling, Lindsay J; Berthold, Deborah A; Nesbitt, Anna E; Gennis, Robert B; Rienstra, Chad M Journal of the American Chemical Society 21375236 2011 Mar 30
Generation of recombinant guinea pig antibody fragments to the human GABAC receptor. Memic, Adnan; Volgina, Veronica V; Gussin, Helene A; Pepperberg, David R; Kay, Brian K Journal of immunological methods 21362428 2011 May 31
Structure-factor analysis of femtosecond microdiffraction patterns from protein nanocrystals. Kirian, Richard A; White, Thomas A; Holton, James M; Chapman, Henry N; Fromme, Petra; Barty, Anton; Lomb, Lukas; Aquila, Andrew; Maia, Filipe R N C; Martin, Andrew V; Fromme, Raimund; Wang, Xiaoyu; Hunter, Mark S; Schmidt, Kevin E; Spence, John C H Acta crystallographica. Section A, Foundations of crystallography 21325716 2011 Mar
Functional implications of an intermeshing cogwheel-like interaction between TolC and MacA in the action of macrolide-specific efflux pump MacAB-TolC. Xu, Yongbin; Song, Saemee; Moeller, Arne; Kim, Nahee; Piao, Shunfu; Sim, Se-Hoon; Kang, Mooseok; Yu, Wookyung; Cho, Hyun-Soo; Chang, Iksoo; Lee, Kangseok; Ha, Nam-Chul The Journal of biological chemistry 21325274 2011 Apr 15
Local and global dynamics of the G protein-coupled receptor CXCR1. Park, Sang Ho; Casagrande, Fabio; Das, Bibhuti B; Albrecht, Lauren; Chu, Mignon; Opella, Stanley J Biochemistry 21323370 2011 Mar 29
Bacterial expression, purification, and model membrane reconstitution of the transmembrane and cytoplasmic domains of the human APP binding protein LR11/SorLA for NMR studies. Wang, Xingsheng; Gill Jr, Richard L; Zhu, Qin; Tian, Fang Protein expression and purification 21320603 2011 Jun
Consequences of the overexpression of a eukaryotic membrane protein, the human KDEL receptor, in Escherichia coli. Klepsch, Mirjam M; Persson, Jan O; de Gier, Jan-Willem L Journal of molecular biology 21316372 2011 Apr 8
A general assignment method for oriented sample (OS) solid-state NMR of proteins based on the correlation of resonances through heteronuclear dipolar couplings in samples aligned parallel and perpendicular to the magnetic field. Lu, George J; Son, Woo Sung; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 21316275 2011 Apr
Drop-out phagemid vector for switching from phage displayed affinity reagents to expression formats. Pershad, Kritika; Sullivan, Mark A; Kay, Brian K Analytical biochemistry 21315061 2011 May 15
Straightforward, effective calibration of SPINAL-64 decoupling results in the enhancement of sensitivity and resolution of biomolecular solid-state NMR. Comellas, Gemma; Lopez, Jakob J; Nieuwkoop, Andrew J; Lemkau, Luisel R; Rienstra, Chad M Journal of magnetic resonance (San Diego, Calif. : 1997) 21296014 2011 Apr
Atomic view of calcium-induced clustering of phosphatidylserine in mixed lipid bilayers. Boettcher, John M; Davis-Harrison, Rebecca L; Clay, Mary C; Nieuwkoop, Andrew J; Ohkubo, Y Zenmei; Tajkhorshid, Emad; Morrissey, James H; Rienstra, Chad M Biochemistry 21294564 2011 Mar 29
Single mimivirus particles intercepted and imaged with an X-ray laser. Seibert, M Marvin; Ekeberg, Tomas; Maia, Filipe R N C; Svenda, Martin; Andreasson, Jakob; Jonsson, Olof; Odic, Dusko; Iwan, Bianca; Rocker, Andrea; Westphal, Daniel; Hantke, Max; DePonte, Daniel P; Barty, Anton; Schulz, Joachim; Gumprecht, Lars; Coppola, Nature 21293374 2011 Feb 3
Femtosecond X-ray protein nanocrystallography. Chapman, Henry N; Fromme, Petra; Barty, Anton; White, Thomas A; Kirian, Richard A; Aquila, Andrew; Hunter, Mark S; Schulz, Joachim; DePonte, Daniel P; Weierstall, Uwe; Doak, R Bruce; Maia, Filipe R N C; Martin, Andrew V; Schlichting, Ilme; Lomb, Lukas; Co Nature 21293373 2011 Feb 3
Site-directed alkylation studies with LacY provide evidence for the alternating access model of transport. Jiang, Xiaoxu; Nie, Yiling; Kaback, H Ronald Biochemistry 21254783 2011 Mar 15
NdhP and NdhQ: two novel small subunits of the cyanobacterial NDH-1 complex. Nowaczyk, Marc M; Wulfhorst, Hannes; Ryan, Christopher M; Souda, Puneet; Zhang, Huamin; Cramer, William A; Whitelegge, Julian P Biochemistry 21244052 2011 Feb 22
Evidence for the presence of a critical disulfide bond in the mouse EP3ýý receptor. Downey, Jason D; Sanders, Charles R; Breyer, Richard M Prostaglandins & other lipid mediators 21236356 2011 Feb
Structure and function of an irreversible agonist-ýý(2) adrenoceptor complex. Rosenbaum, Daniel M; Zhang, Cheng; Lyons, Joseph A; Holl, Ralph; Aragao, David; Arlow, Daniel H; Rasmussen, Soren G F; Choi, Hee-Jung; Devree, Brian T; Sunahara, Roger K; Chae, Pil Seok; Gellman, Samuel H; Dror, Ron O; Shaw, David E; Weis, William I; Caff Nature 21228876 2011 Jan 13
Structure of a nanobody-stabilized active state of the ýý(2) adrenoceptor. Rasmussen, Soren G F; Choi, Hee-Jung; Fung, Juan Jose; Pardon, Els; Casarosa, Paola; Chae, Pil Seok; Devree, Brian T; Rosenbaum, Daniel M; Thian, Foon Sun; Kobilka, Tong Sun; Schnapp, Andreas; Konetzki, Ingo; Sunahara, Roger K; Gellman, Samuel H; Pautsch, Nature 21228869 2011 Jan 13
Conversion of scFv peptide-binding specificity for crystal chaperone development. Pai, Jennifer C; Culver, Jeffrey A; Drury, Jason E; Motani, Rakesh S; Lieberman, Raquel L; Maynard, Jennifer A Protein engineering, design & selection : PEDS 21217145 2011 May
Crystal structure of arrestin-3 reveals the basis of the difference in receptor binding between two non-visual subtypes. Zhan, Xuanzhi; Gimenez, Luis E; Gurevich, Vsevolod V; Spiller, Benjamin W Journal of molecular biology 21215759 2011 Feb 25
Systematic analysis of native membrane protein complexes in Escherichia coli. Maddalo, Gianluca; Stenberg-Bruzell, Filippa; Gotzke, Hansjorg; Toddo, Stephen; Bjorkholm, Patrik; Eriksson, Hanna; Chovanec, Peter; Genevaux, Pierre; Lehtio, Janne; Ilag, Leopold L; Daley, Daniel O Journal of proteome research 21210718 2011 Apr 1
RDC derived protein backbone resonance assignment using fragment assembly. Wang, Xingsheng; Tash, Brian; Flanagan, John M; Tian, Fang Journal of biomolecular NMR 21191805 2011 Feb
Detection of membrane protein two-dimensional crystals in living cells. Gualtieri, E J; Guo, F; Kissick, D J; Jose, J; Kuhn, R J; Jiang, W; Simpson, G J Biophysical journal 21190673 2011 Jan 5
X-ray diffraction from membrane protein nanocrystals. Hunter, M S; DePonte, D P; Shapiro, D A; Kirian, R A; Wang, X; Starodub, D; Marchesini, S; Weierstall, U; Doak, R B; Spence, J C H; Fromme, P Biophysical journal 21190672 2011 Jan 5
The alternating access transport mechanism in LacY. Kaback, H Ronald; Smirnova, Irina; Kasho, Vladimir; Nie, Yiling; Zhou, Yonggang The Journal of membrane biology 21161516 2011 Jan
Immunodominant T cell determinants of aquaporin-4, the autoantigen associated with neuromyelitis optica. Nelson, Patricia A; Khodadoust, Mojgan; Prodhomme, Thomas; Spencer, Collin; Patarroyo, Juan Carlos; Varrin-Doyer, Michel; Ho, Joseph D; Stroud, Robert M; Zamvil, Scott S PloS one 21151500 2010
Mechanism of melibiose/cation symport of the melibiose permease of Salmonella typhimurium. Guan, Lan; Nurva, Shailika; Ankeshwarapu, Siva P The Journal of biological chemistry 21148559 2011 Feb 25
Present and future of membrane protein structure determination by electron crystallography. Ubarretxena-Belandia, Iban; Stokes, David L Advances in protein chemistry and structural biology 21115172 2010
Statistical treatment of photon/electron counting: extending the linear dynamic range from the dark count rate to saturation. Kissick, David J; Muir, Ryan D; Simpson, Garth J Analytical chemistry 21114249 2010 Dec 15
Crystallizing membrane proteins for structure determination using lipidic mesophases. Caffrey, Martin; Porter, Christopher Journal of visualized experiments : JoVE 21113125 2010
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Chien, Ellen Y T; Liu, Wei; Zhao, Qiang; Katritch, Vsevolod; Han, Gye Won; Hanson, Michael A; Shi, Lei; Newman, Amy Hauck; Javitch, Jonathan A; Cherezov, Vadim; Stevens, Raymond C Science (New York, N.Y.) 21097933 2010 Nov 19
GFT projection NMR spectroscopy for proteins in the solid state. Franks, W Trent; Atreya, Hanudatta S; Szyperski, Thomas; Rienstra, Chad M Journal of biomolecular NMR 21052779 2010 Dec
Elucidation of inositol hexaphosphate and heparin interaction sites and conformational changes in arrestin-1 by solution nuclear magnetic resonance. Zhuang, Tiandi; Vishnivetskiy, Sergey A; Gurevich, Vsevolod V; Sanders, Charles R Biochemistry 21050017 2010 Dec 14
Tandem facial amphiphiles for membrane protein stabilization. Chae, Pil Seok; Gotfryd, Kamil; Pacyna, Jennifer; Miercke, Larry J W; Rasmussen, Soren G F; Robbins, Rebecca A; Rana, Rohini R; Loland, Claus J; Kobilka, Brian; Stroud, Robert; Byrne, Bernadette; Gether, Ulrik; Gellman, Samuel H Journal of the American Chemical Society 21049926 2010 Dec 1
Method to measure strong protein-protein interactions in lipid bilayers using a steric trap. Hong, Heedeok; Blois, Tracy M; Cao, Zheng; Bowie, James U Proceedings of the National Academy of Sciences of the United States of America 21041662 2010 Nov 16
Maltose-neopentyl glycol (MNG) amphiphiles for solubilization, stabilization and crystallization of membrane proteins. Chae, Pil Seok; Rasmussen, Soren G F; Rana, Rohini R; Gotfryd, Kamil; Chandra, Richa; Goren, Michael A; Kruse, Andrew C; Nurva, Shailika; Loland, Claus J; Pierre, Yves; Drew, David; Popot, Jean-Luc; Picot, Daniel; Fox, Brian G; Guan, Lan; Gether, Ulrik; B Nature methods 21037590 2010 Dec
Restrained expression, a method to overproduce toxic membrane proteins by exploiting operator-repressor interactions. Narayanan, Anoop; Ridilla, Marc; Yernool, Dinesh A Protein science : a publication of the Protein Society 21031485 2011 Jan
Membranes in balance: mechanisms of sphingolipid homeostasis. Breslow, David K; Weissman, Jonathan S Molecular cell 20965421 2010 Oct 22
Phosphoramidate end labeling of inorganic polyphosphates: facile manipulation of polyphosphate for investigating and modulating its biological activities. Choi, Sharon H; Collins, Julie N R; Smith, Stephanie A; Davis-Harrison, Rebecca L; Rienstra, Chad M; Morrissey, James H Biochemistry 20957999 2010 Nov 16
A Stochastic Model for Nucleation Kinetics Determination in Droplet-Based Microfluidic Systems. Goh, Limay; Chen, Kejia; Bhamidi, Venkateswarlu; He, Guangwen; Kee, Nicholas C S; Kenis, Paul J A; Zukoski, Charles F; Braatz, Richard D Crystal growth & design 20953348 2010 May 10
Overexpression and purification of integral membrane proteins in yeast. Hays, Franklin A; Roe-Zurz, Zygy; Stroud, Robert M Methods in enzymology 20946832 2010
Automated protein resonance assignments of magic angle spinning solid-state NMR spectra of ýý1 immunoglobulin binding domain of protein G (GB1). Moseley, Hunter N B; Sperling, Lindsay J; Rienstra, Chad M Journal of biomolecular NMR 20931264 2010 Nov
Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Wu, Beili; Chien, Ellen Y T; Mol, Clifford D; Fenalti, Gustavo; Liu, Wei; Katritch, Vsevolod; Abagyan, Ruben; Brooun, Alexei; Wells, Peter; Bi, F Christopher; Hamel, Damon J; Kuhn, Peter; Handel, Tracy M; Cherezov, Vadim; Stevens, Raymond C Science (New York, N.Y.) 20929726 2010 Nov 19
Consequences of depletion of the signal recognition particle in Escherichia coli. Wickstrom, David; Wagner, Samuel; Baars, Louise; Ytterberg, A Jimmy; Klepsch, Mirjam; van Wijk, Klaas J; Luirink, Joen; de Gier, Jan-Willem The Journal of biological chemistry 20923772 2011 Feb 11
CHOBIMALT: a cholesterol-based detergent. Howell, Stanley C; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Breyer, Richard M; Sanders, Charles R Biochemistry 20919740 2010 Nov 9
Helical crystallization of two example membrane proteins MsbA and the Ca(2+)-ATPase. Glaves, John Paul; Fisher, Lauren; Ward, Andrew; Young, Howard S Methods in enzymology 20888473 2010
Helical crystallization of soluble and membrane binding proteins. Wilson-Kubalek, Elizabeth M; Chappie, Joshua S; Arthur, Christopher P Methods in enzymology 20887852 2010
Expression, refolding, and initial structural characterization of the Y. pestis Ail outer membrane protein in lipids. Plesniak, Leigh A; Mahalakshmi, Radhakrishnan; Rypien, Candace; Yang, Yuan; Racic, Jasmina; Marassi, Francesca M Biochimica et biophysica acta 20883662 2011 Jan
Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography. Wilderman, P Ross; Shah, Manish B; Liu, Tong; Li, Sheng; Hsu, Simon; Roberts, Arthur G; Goodlett, David R; Zhang, Qinghai; Woods Jr, Virgil L; Stout, C David; Halpert, James R The Journal of biological chemistry 20880847 2010 Dec 3
Total chemical synthesis and X-ray structure of kaliotoxin by racemic protein crystallography. Pentelute, Brad L; Mandal, Kalyaneswar; Gates, Zachary P; Sawaya, Michael R; Yeates, Todd O; Kent, Stephen B H Chemical communications (Cambridge, England) 20877851 2010 Nov 21
Structure of a cation-bound multidrug and toxic compound extrusion transporter. He, Xiao; Szewczyk, Paul; Karyakin, Andrey; Evin, Mariah; Hong, Wen-Xu; Zhang, Qinghai; Chang, Geoffrey Nature 20861838 2010 Oct 21
Structural context shapes the aquaporin selectivity filter. Savage, David F; O'Connell 3rd, Joseph D; Miercke, Larry J W; Finer-Moore, Janet; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 20855585 2010 Oct 5
Simultaneous structure and dynamics of a membrane protein using REDCRAFT: membrane-bound form of Pf1 coat protein. Shealy, Paul; Simin, Mikhail; Park, Sang Ho; Opella, Stanley J; Valafar, Homayoun Journal of magnetic resonance (San Diego, Calif. : 1997) 20829084 2010 Nov
Structures of cytochrome P450 2B4 complexed with the antiplatelet drugs ticlopidine and clopidogrel . Gay, Sean C; Roberts, Arthur G; Maekawa, Keiko; Talakad, Jyothi C; Hong, Wen-Xu; Zhang, Qinghai; Stout, C David; Halpert, James R Biochemistry 20815363 2010 Oct 12
Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance. Kijac, Aleksandra; Shih, Amy Y; Nieuwkoop, Andrew J; Schulten, Klaus; Sligar, Stephen G; Rienstra, Chad M Biochemistry 20804175 2010 Nov 2
High resolution ýýýýC-detected solid-state NMR spectroscopy of a deuterated protein. Tang, Ming; Comellas, Gemma; Mueller, Leonard J; Rienstra, Chad M Journal of biomolecular NMR 20803233 2010 Oct
Unlocking the eukaryotic membrane protein structural proteome. Lee, John Kyongwon; Stroud, Robert Michael Current opinion in structural biology 20739007 2010 Aug
Substrate and drug binding sites in LeuT. Nyola, Ajeeta; Karpowich, Nathan K; Zhen, Juan; Marden, Jennifer; Reith, Maarten E; Wang, Da-Neng Current opinion in structural biology 20739005 2010 Aug
Triton X-100 as the "short-chain lipid" improves the magnetic alignment and stability of membrane proteins in phosphatidylcholine bilayers for oriented-sample solid-state NMR spectroscopy. Park, Sang Ho; Opella, Stanley J Journal of the American Chemical Society 20735058 2010 Sep 15
Secondary structure, dynamics, and architecture of the p7 membrane protein from hepatitis C virus by NMR spectroscopy. Cook, Gabriel A; Opella, Stanley J Biochimica et biophysica acta 20727850 2011 Jun
Comparative NMR studies demonstrate profound differences between two viroporins: p7 of HCV and Vpu of HIV-1. Cook, Gabriel A; Zhang, Hua; Park, Sang Ho; Wang, Yan; Opella, Stanley J Biochimica et biophysica acta 20727848 2011 Feb
Polyphosphate exerts differential effects on blood clotting, depending on polymer size. Smith, Stephanie A; Choi, Sharon H; Davis-Harrison, Rebecca; Huyck, Jillian; Boettcher, John; Rienstra, Chad M; Reinstra, Chad M; Morrissey, James H Blood 20709905 2010 Nov 18
The 3D structures of VDAC represent a native conformation. Hiller, Sebastian; Abramson, Jeff; Mannella, Carmen; Wagner, Gerhard; Zeth, Kornelius Trends in biochemical sciences 20708406 2010 Sep
Crystal structure of the ligand-binding domain of the promiscuous EphA4 receptor reveals two distinct conformations. Singla, Nikhil; Goldgur, Yehuda; Xu, Kai; Paavilainen, Sari; Nikolov, Dimitar B; Himanen, Juha P Biochemical and biophysical research communications 20678482 2010 Sep 3
Conserved binding mode of human beta2 adrenergic receptor inverse agonists and antagonist revealed by X-ray crystallography. Wacker, Daniel; Fenalti, Gustavo; Brown, Monica A; Katritch, Vsevolod; Abagyan, Ruben; Cherezov, Vadim; Stevens, Raymond C Journal of the American Chemical Society 20669948 2010 Aug 25
Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Banigan, James R; Mandal, Kalyaneswar; Sawaya, Michael R; Thammavongsa, Vilasak; Hendrickx, Antoni P A; Schneewind, Olaf; Yeates, Todd O; Kent, Stephen B H Protein science : a publication of the Protein Society 20669184 2010 Oct
A high-throughput differential filtration assay to screen and select detergents for membrane proteins. Vergis, James M; Purdy, Michael D; Wiener, Michael C Analytical biochemistry 20667442 2010 Dec 1
Two-dimensional crystallization of integral membrane proteins for electron crystallography. Stokes, David L; Rice, William J; Hu, Minghui; Kim, Changki; Ubarretxena-Belandia, Iban Methods in molecular biology (Clifton, N.J.) 20665267 2010
Recent progress in the structure determination of GPCRs, a membrane protein family with high potential as pharmaceutical targets. Cherezov, Vadim; Abola, Enrique; Stevens, Raymond C Methods in molecular biology (Clifton, N.J.) 20665265 2010
1H-13C separated local field spectroscopy of uniformly 13C labeled peptides and proteins. Lin, Eugene C; Wu, Chin H; Yang, Yuan; Grant, Christopher V; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 20637662 2010 Sep
Probing the role of CXC motif in chemokine CXCL8 for high affinity binding and activation of CXCR1 and CXCR2 receptors. Joseph, Prem Raj B; Sarmiento, Jose M; Mishra, Anurag K; Das, Sandhya T; Garofalo, Roberto P; Navarro, Javier; Rajarathnam, Krishna The Journal of biological chemistry 20630874 2010 Sep 17
Observation of organometallic and radical intermediates formed during the reaction of methyl-coenzyme M reductase with bromoethanesulfonate. Li, Xianghui; Telser, Joshua; Kunz, Ryan C; Hoffman, Brian M; Gerfen, Gary; Ragsdale, Stephen W Biochemistry 20597483 2010 Aug 17
Nonmicellar systems for solution NMR spectroscopy of membrane proteins. Raschle, Thomas; Hiller, Sebastian; Etzkorn, Manuel; Wagner, Gerhard Current opinion in structural biology 20570504 2010 Aug
Delineating electrogenic reactions during lactose/H+ symport. Garcia-Celma, Juan J; Ploch, Julian; Smirnova, Irina; Kaback, H Ronald; Fendler, Klaus Biochemistry 20568736 2010 Jul 27
Expression of neurotransmitter transporters for structural and biochemical studies. Elbaz, Yael; Danieli, Tsafi; Kanner, Baruch I; Schuldiner, Shimon Protein expression and purification 20566324 2010 Oct
NMR Determination of Protein pK(a) Values in the Solid State. Schmidt, Heather L Frericks; Shah, Gautam J; Sperling, Lindsay J; Rienstra, Chad M The journal of physical chemistry letters 20563223 2010 May 4
Expression and purification of the membrane protein p7 from hepatitis C virus. Cook, Gabriel A; Stefer, Susanne; Opella, Stanley J Biopolymers 20560141 2011
Backbone 1H, 13C and 15N resonance assignments of the extracellular domain of tissue factor. Boettcher, John M; Clay, Mary C; LaHood, Benjamin J; Morrissey, James H; Rienstra, Chad M Biomolecular NMR assignments 20526825 2010 Oct
A resonance assignment method for oriented-sample solid-state NMR of proteins. Knox, Robert W; Lu, George J; Opella, Stanley J; Nevzorov, Alexander A Journal of the American Chemical Society 20509649 2010 Jun 23
Design and folding of [GluA4(ObetaThrB30)]insulin ("ester insulin"): a minimal proinsulin surrogate that can be chemically converted into human insulin. Sohma, Youhei; Hua, Qing-Xin; Whittaker, Jonathan; Weiss, Michael A; Kent, Stephen B H Angewandte Chemie (International ed. in English) 20509131 2010 Jul 26
Architecture of Eph receptor clusters. Himanen, Juha P; Yermekbayeva, Laila; Janes, Peter W; Walker, John R; Xu, Kai; Atapattu, Lakmali; Rajashankar, Kanagalaghatta R; Mensinga, Anneloes; Lackmann, Martin; Nikolov, Dimitar B; Dhe-Paganon, Sirano Proceedings of the National Academy of Sciences of the United States of America 20505120 2010 Jun 15
Antagonistic anti-urokinase plasminogen activator receptor (uPAR) antibodies significantly inhibit uPAR-mediated cellular signaling and migration. Duriseti, Sai; Goetz, David H; Hostetter, Daniel R; LeBeau, Aaron M; Wei, Ying; Craik, Charles S The Journal of biological chemistry 20501655 2010 Aug 27
A Plug-Based Microfluidic System for Dispensing Lipidic Cubic Phase (LCP) Material Validated by Crystallizing Membrane Proteins in Lipidic Mesophases. Li, Liang; Fu, Qiang; Kors, Christopher A; Stewart, Lance; Nollert, Peter; Laible, Philip D; Ismagilov, Rustem F Microfluidics and nanofluidics 20473353 2010 Jun
Biophysics: Transporter in the spotlight. Karpowich, Nathan K; Wang, Da-Neng Nature 20463728 2010 May 13
Molecular mechanism of MLL PHD3 and RNA recognition by the Cyp33 RRM domain. Hom, Robert A; Chang, Pei-Yun; Roy, Siddhartha; Musselman, Catherine A; Glass, Karen C; Selezneva, Anna I; Gozani, Or; Ismagilov, Rustem F; Cleary, Michael L; Kutateladze, Tatiana G Journal of molecular biology 20460131 2010 Jul 9
Function of human Rh based on structure of RhCG at 2.1 A. Gruswitz, Franz; Chaudhary, Sarika; Ho, Joseph D; Schlessinger, Avner; Pezeshki, Bobak; Ho, Chi-Min; Sali, Andrej; Westhoff, Connie M; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 20457942 2010 May 25
Sugar binding induces the same global conformational change in purified LacY as in the native bacterial membrane. Nie, Yiling; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 20457922 2010 May 25
Backbone and ILV side chain methyl group assignments of the integral human membrane protein VDAC-1. Hiller, Sebastian; Malia, Thomas J; Garces, Robert G; Orekhov, Vladislav Y; Wagner, Gerhard Biomolecular NMR assignments 20437141 2010 Apr
Probes for high field solid-state NMR of lossy biological samples. Grant, Christopher V; Wu, Chin H; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 20435493 2010 Jun
LCP-Tm: an assay to measure and understand stability of membrane proteins in a membrane environment. Liu, Wei; Hanson, Michael A; Stevens, Raymond C; Cherezov, Vadim Biophysical journal 20409473 2010 Apr 21
Assignment strategies for large proteins by magic-angle spinning NMR: the 21-kDa disulfide-bond-forming enzyme DsbA. Sperling, Lindsay J; Berthold, Deborah A; Sasser, Terry L; Jeisy-Scott, Victoria; Rienstra, Chad M Journal of molecular biology 20394752 2010 Jun 4
Femtosecond protein nanocrystallography-data analysis methods. Kirian, Richard A; Wang, Xiaoyu; Weierstall, Uwe; Schmidt, Kevin E; Spence, John C H; Hunter, Mark; Fromme, Petra; White, Thomas; Chapman, Henry N; Holton, James Optics express 20389587 2010 Mar 15
Structural basis for solute transport, nucleotide regulation, and immunological recognition of Neisseria meningitidis PorB. Tanabe, Mikio; Nimigean, Crina M; Iverson, T M Proceedings of the National Academy of Sciences of the United States of America 20351243 2010 Apr 13
An automated pipeline to screen membrane protein 2D crystallization. Kim, Changki; Vink, Martin; Hu, Minghui; Love, James; Stokes, David L; Ubarretxena-Belandia, Iban Journal of structural and functional genomics 20349145 2010 Jun
Determination of the phase diagram for soluble and membrane proteins. Talreja, Sameer; Perry, Sarah L; Guha, Sudipto; Bhamidi, Venkateswarlu; Zukoski, Charles F; Kenis, Paul J A The journal of physical chemistry. B 20235520 2010 Apr 8
Design, synthesis, and properties of branch-chained maltoside detergents for stabilization and crystallization of integral membrane proteins: human connexin 26. Hong, Wen-Xu; Baker, Kent A; Ma, Xingquan; Stevens, Raymond C; Yeager, Mark; Zhang, Qinghai Langmuir : the ACS journal of surfaces and colloids 20232919 2010 Jun 1
Mycobacterium tuberculosis Rv0899 adopts a mixed alpha/beta-structure and does not form a transmembrane beta-barrel. Teriete, Peter; Yao, Yong; Kolodzik, Adrian; Yu, Jinghua; Song, Houhui; Niederweis, Michael; Marassi, Francesca M Biochemistry 20199110 2010 Apr 6
Automated electron microscopy for evaluating two-dimensional crystallization of membrane proteins. Hu, Minghui; Vink, Martin; Kim, Changki; Derr, Kd; Koss, John; D'Amico, Kevin; Cheng, Anchi; Pulokas, James; Ubarretxena-Belandia, Iban; Stokes, David Journal of structural biology 20197095 2010 Jul
Protein crystallization using microfluidic technologies based on valves, droplets, and SlipChip. Li, Liang; Ismagilov, Rustem F Annual review of biophysics 20192773 2010
Orm family proteins mediate sphingolipid homeostasis. Breslow, David K; Collins, Sean R; Bodenmiller, Bernd; Aebersold, Ruedi; Simons, Kai; Shevchenko, Andrej; Ejsing, Christer S; Weissman, Jonathan S Nature 20182505 2010 Feb 25
Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins. Kim, Hak Jun; Howell, Stanley C; Van Horn, Wade D; Jeon, Young Ho; Sanders, Charles R Progress in nuclear magnetic resonance spectroscopy 20161395 2009 Nov 1
Microfluidic Generation of Lipidic Mesophases for Membrane Protein Crystallization. Perry, Sarah L; Roberts, Griffin W; Tice, Joshua D; Gennis, Robert B; Kenis, Paul J A Crystal growth & design 20161169 2009 Jun 3
An Escherichia coli-based cell-free system for large-scale production of functional mammalian membrane proteins suitable for X-ray crystallography. Nguyen, Tuan A; Lieu, Samantha S; Chang, Geoffrey Journal of molecular microbiology and biotechnology 20160448 2010
NMR structure determination for larger proteins using backbone-only data. Raman, Srivatsan; Lange, Oliver F; Rossi, Paolo; Tyka, Michael; Wang, Xu; Aramini, James; Liu, Gaohua; Ramelot, Theresa A; Eletsky, Alexander; Szyperski, Thomas; Kennedy, Michael A; Prestegard, James; Montelione, Gaetano T; Baker, David Science (New York, N.Y.) 20133520 2010 Feb 19
The structure of p85ni in class IA phosphoinositide 3-kinase exhibits interdomain disorder. Sen, K Ilker; Wu, Haiyan; Backer, Jonathan M; Gerfen, Gary J Biochemistry 20131869 2010 Mar 16
Protein-phospholipid interactions in blood clotting. Morrissey, James H; Davis-Harrison, Rebecca L; Tavoosi, Narjes; Ke, Ke; Pureza, Vincent; Boettcher, John M; Clay, Mary C; Rienstra, Chad M; Ohkubo, Y Zenmei; Pogorelov, Taras V; Tajkhorshid, Emad Thrombosis research 20129649 2010 Apr
Crystallographic characterization of N-oxide tripod amphiphiles. Chae, Pil Seok; Guzei, Ilia A; Gellman, Samuel H Journal of the American Chemical Society 20095541 2010 Feb 17
Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl)imidazole at 2.0-A resolution. Gay, Sean C; Shah, Manish B; Talakad, Jyothi C; Maekawa, Keiko; Roberts, Arthur G; Wilderman, P Ross; Sun, Ling; Yang, Jane Y; Huelga, Stephanie C; Hong, Wen-Xu; Zhang, Qinghai; Stout, C David; Halpert, James R Molecular pharmacology 20061448 2010 Apr
Dynamics of the beta2-adrenergic G-protein coupled receptor revealed by hydrogen-deuterium exchange. Zhang, Xi; Chien, Ellen Y T; Chalmers, Michael J; Pascal, Bruce D; Gatchalian, Jovylyn; Stevens, Raymond C; Griffin, Patrick R Analytical chemistry 20058880 2010 Feb 1
Presentation of membrane-anchored glycosphingolipids determined from molecular dynamics simulations and NMR paramagnetic relaxation rate enhancement. Demarco, Mari L; Woods, Robert J; Prestegard, James H; Tian, Fang Journal of the American Chemical Society 20058858 2010 Feb 3
EPR characterization of ascorbyl and sulfur dioxide anion radicals trapped during the reaction of bovine Cytochrome c Oxidase with molecular oxygen. Yu, Michelle A; Egawa, Tsuyoshi; Yeh, Syun-Ru; Rousseau, Denis L; Gerfen, Gary J Journal of magnetic resonance (San Diego, Calif. : 1997) 20056464 2010 Apr
Helix dynamics in LacY: helices II and IV. Liu, Zhenyu; Madej, M Gregor; Kaback, H Ronald Journal of molecular biology 20043916 2010 Feb 26
Nonlinear optical imaging of integral membrane protein crystals in lipidic mesophases. Kissick, David J; Gualtieri, Ellen J; Simpson, Garth J; Cherezov, Vadim Analytical chemistry 20025250 2010 Jan 15
Directed evolution reveals hidden properties of VMAT, a neurotransmitter transporter. Gros, Yael; Schuldiner, Shimon The Journal of biological chemistry 20007701 2010 Feb 12
Multiparameter screening on SlipChip used for nanoliter protein crystallization combining free interface diffusion and microbatch methods. Li, Liang; Du, Wenbin; Ismagilov, Rustem F Journal of the American Chemical Society 20000709 2010 Jan 13
User-loaded SlipChip for equipment-free multiplexed nanoliter-scale experiments. Li, Liang; Du, Wenbin; Ismagilov, Rustem Journal of the American Chemical Society 20000708 2010 Jan 13
Crystal structure of CYP24A1, a mitochondrial cytochrome P450 involved in vitamin D metabolism. Annalora, Andrew J; Goodin, David B; Hong, Wen-Xu; Zhang, Qinghai; Johnson, Eric F; Stout, C David Journal of molecular biology 19961857 2010 Feb 19
Probing of the rates of alternating access in LacY with Trp fluorescence. Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 19959662 2009 Dec 22
High resolution NMR spectroscopy of nanocrystalline proteins at ultra-high magnetic field. Sperling, Lindsay J; Nieuwkoop, Andrew J; Lipton, Andrew S; Berthold, Deborah A; Rienstra, Chad M Journal of biomolecular NMR 19953303 2010 Feb
NMR characterization of membrane protein-detergent micelle solutions by use of microcoil equipment. Stanczak, Pawel; Horst, Reto; Serrano, Pedro; Wuthrich, Kurt Journal of the American Chemical Society 19950959 2009 Dec 30
The effect of calcium on the conformation of cobalamin transporter BtuB. Luan, Binquan; Carr, Rogan; Caffrey, Martin; Aksimentiev, Aleksei Proteins 19927326 2010 Apr
Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. Raschle, Thomas; Hiller, Sebastian; Yu, Tsyr-Yan; Rice, Amanda J; Walz, Thomas; Wagner, Gerhard Journal of the American Chemical Society 19916553 2009 Dec 16
Regulation of Class IA PI 3-kinases: C2 domain-iSH2 domain contacts inhibit p85/p110alpha and are disrupted in oncogenic p85 mutants. Wu, Haiyan; Shekar, S Chandra; Flinn, Rory J; El-Sibai, Mirvat; Jaiswal, Bijay S; Sen, K Ilker; Janakiraman, Vasantharajan; Seshagiri, Somasekar; Gerfen, Gary J; Girvin, Mark E; Backer, Jonathan M Proceedings of the National Academy of Sciences of the United States of America 19915146 2009 Dec 1
Bolaamphiphile-class surfactants can stabilize and support the function of solubilized integral membrane proteins. Li, Qingxin; Mittal, Ritesh; Huang, Lijun; Travis, Benjamin; Sanders, Charles R Biochemistry 19908902 2009 Dec 15
(1)H-(13)C Hetero-nuclear dipole-dipole couplings of methyl groups in stationary and magic angle spinning solid-state NMR experiments of peptides and proteins. Wu, Chin H; Das, Bibhuti B; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 19896874 2010 Feb
Expression, purification and preliminary X-ray analysis of the Neisseria meningitidis outer membrane protein PorB. Tanabe, Mikio; Iverson, Tina M Acta crystallographica. Section F, Structural biology and crystallization communications 19851005 2009 Oct 1
Biomimetic synthesis of lispro insulin via a chemically synthesized "mini-proinsulin" prepared by oxime-forming ligation. Sohma, Youhei; Kent, Stephen B H Journal of the American Chemical Society 19835355 2009 Nov 11
Structural imperatives impose diverse evolutionary constraints on helical membrane proteins. Oberai, Amit; Joh, Nathan H; Pettit, Frank K; Bowie, James U Proceedings of the National Academy of Sciences of the United States of America 19815527 2009 Oct 20
Labeling strategies for 13C-detected aligned-sample solid-state NMR of proteins. Filipp, Fabian V; Sinha, Neeraj; Jairam, Lena; Bradley, Joel; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 19781966 2009 Dec
Effects of impurities on membrane-protein crystallization in different systems. Kors, Christopher A; Wallace, Ellen; Davies, Douglas R; Li, Liang; Laible, Philip D; Nollert, Peter Acta crystallographica. Section D, Biological crystallography 19770503 2009 Oct
Backbone and side-chain (1)H, (13)C and (15)N resonance assignments of LEN, a human immunoglobulin kappaIV light-chain variable domain. Mukherjee, Sujoy; Pondaven, Simon P; Hofer, Nicole; Jaroniec, Christopher P Biomolecular NMR assignments 19768664 2009 Dec
Phage-induced alignment of membrane proteins enables the measurement and structural analysis of residual dipolar couplings with dipolar waves and lambda-maps. Park, Sang Ho; Son, Woo Sung; Mukhopadhyay, Rishi; Valafar, Homayoun; Opella, Stanley J Journal of the American Chemical Society 19761238 2009 Oct 14
A survey of integral alpha-helical membrane proteins. Kelly, Libusha; Pieper, Ursula; Eswar, Narayanan; Hays, Franklin A; Li, Min; Roe-Zurz, Zygy; Kroetz, Deanna L; Giacomini, Kathleen M; Stroud, Robert M; Sali, Andrej Journal of structural and functional genomics 19760129 2009 Dec
Protein unfolding with a steric trap. Blois, Tracy M; Hong, Heedeok; Kim, Tae H; Bowie, James U Journal of the American Chemical Society 19739627 2009 Oct 7
Coupled decomposition of four-dimensional NOESY spectra. Hiller, Sebastian; Ibraghimov, Ilghis; Wagner, Gerhard; Orekhov, Vladislav Y Journal of the American Chemical Society 19737017 2009 Sep 16
A Modified Alderman-Grant Coil makes possible an efficient cross-coil probe for high field solid-state NMR of lossy biological samples. Grant, Christopher V; Yang, Yuan; Glibowicka, Mira; Wu, Chin H; Park, Sang Ho; Deber, Charles M; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 19733108 2009 Nov
NMR studies of p7 protein from hepatitis C virus. Cook, Gabriel A; Opella, Stanley J European biophysics journal : EBJ 19727701 2010 Jun
Properties of a LacY efflux mutant. Guan, Lan; Kaback, H Ronald Biochemistry 19719233 2009 Oct 6
Residues in the H+ translocation site define the pKa for sugar binding to LacY. Smirnova, Irina; Kasho, Vladimir; Sugihara, Junichi; Choe, Jun-Yong; Kaback, H Ronald Biochemistry 19689129 2009 Sep 22
The role of solution NMR in the structure determinations of VDAC-1 and other membrane proteins. Hiller, Sebastian; Wagner, Gerhard Current opinion in structural biology 19665886 2009 Aug
SlipChip. Du, Wenbin; Li, Liang; Nichols, Kevin P; Ismagilov, Rustem F Lab on a chip 19636458 2009 Aug 21
Protein-membrane interactions: blood clotting on nanoscale bilayers. Morrissey, J H; Pureza, V; Davis-Harrison, R L; Sligar, S G; Rienstra, C M; Kijac, A Z; Ohkubo, Y Z; Tajkhorshid, E Journal of thrombosis and haemostasis : JTH 19630793 2009 Jul
Similar energetic contributions of packing in the core of membrane and water-soluble proteins. Joh, Nathan H; Oberai, Amit; Yang, Duan; Whitelegge, Julian P; Bowie, James U Journal of the American Chemical Society 19603754 2009 Aug 12
A strip-shield improves the efficiency of a solenoid coil in probes for high-field solid-state NMR of lossy biological samples. Wu, Chin H; Grant, Christopher V; Cook, Gabriel A; Park, Sang Ho; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 19559634 2009 Sep
Structural and spectropotentiometric analysis of Blastochloris viridis heterodimer mutant reaction center. Ponomarenko, Nina S; Li, Liang; Marino, Antony R; Tereshko, Valentina; Ostafin, Agnes; Popova, Julia A; Bylina, Edward J; Ismagilov, Rustem F; Norris Jr, James R Biochimica et biophysica acta 19539602 2009 Sep
G-protein-coupled receptor structures were not built in a day. Blois, Tracy M; Bowie, James U Protein science : a publication of the Protein Society 19536805 2009 Jul
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam. Cherezov, Vadim; Hanson, Michael A; Griffith, Mark T; Hilgart, Mark C; Sanishvili, Ruslan; Nagarajan, Venugopalan; Stepanov, Sergey; Fischetti, Robert F; Kuhn, Peter; Stevens, Raymond C Journal of the Royal Society, Interface / the Royal Society 19535414 2009 Oct 6
Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. Himanen, Juha P; Goldgur, Yehuda; Miao, Hui; Myshkin, Eugene; Guo, Hong; Buck, Matthias; Nguyen, My; Rajashankar, Kanagalaghatta R; Wang, Bingcheng; Nikolov, Dimitar B EMBO reports 19525919 2009 Jul
Racemic crystallography of synthetic protein enantiomers used to determine the X-ray structure of plectasin by direct methods. Mandal, Kalyaneswar; Pentelute, Brad L; Tereshko, Valentina; Thammavongsa, Vilasak; Schneewind, Olaf; Kossiakoff, Anthony A; Kent, Stephen B H Protein science : a publication of the Protein Society 19472324 2009 Jun
Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Michino, Mayako; Abola, Enrique; GPCR Dock 2008 participants; Brooks 3rd, Charles L; Dixon, J Scott; Moult, John; Stevens, Raymond C Nature reviews. Drug discovery 19461661 2009 Jun
The T-lock: automated compensation of radio-frequency induced sample heating. Hiller, Sebastian; Arthanari, Haribabu; Wagner, Gerhard Journal of biomolecular NMR 19434373 2009 Jun
Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures. Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Law, Christopher J; Reith, Maarten E A; Wang, Da-Neng Nature structural & molecular biology 19430461 2009 Jun
Crystallizing membrane proteins using lipidic mesophases. Caffrey, Martin; Cherezov, Vadim Nature protocols 19390528 2009
Electrophysiological characterization of LacY. Garcia-Celma, Juan J; Smirnova, Irina N; Kaback, H Ronald; Fendler, Klaus Proceedings of the National Academy of Sciences of the United States of America 19383792 2009 May 5
Crystal structure of human aquaporin 4 at 1.8 A and its mechanism of conductance. Ho, Joseph D; Yeh, Ronald; Sandstrom, Andrew; Chorny, Ilya; Harries, William E C; Robbins, Rebecca A; Miercke, Larry J W; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 19383790 2009 May 5
A general protocol for the crystallization of membrane proteins for X-ray structural investigation. Newby, Zachary E R; O'Connell 3rd, Joseph D; Gruswitz, Franz; Hays, Franklin A; Harries, William E C; Harwood, Ian M; Ho, Joseph D; Lee, John K; Savage, David F; Miercke, Larry J W; Stroud, Robert M Nature protocols 19360018 2009
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes. Katritch, Vsevolod; Reynolds, Kimberly A; Cherezov, Vadim; Hanson, Michael A; Roth, Christopher B; Yeager, Mark; Abagyan, Ruben Journal of molecular recognition : JMR 19353579 2009 Jul-Aug
Efficient and accurate estimation of relative order tensors from lambda-maps. Mukhopadhyay, Rishi; Miao, Xijiang; Shealy, Paul; Valafar, Homayoun Journal of magnetic resonance (San Diego, Calif. : 1997) 19345125 2009 Jun
Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Aller, Stephen G; Yu, Jodie; Ward, Andrew; Weng, Yue; Chittaboina, Srinivas; Zhuo, Rupeng; Harrell, Patina M; Trinh, Yenphuong T; Zhang, Qinghai; Urbatsch, Ina L; Chang, Geoffrey Science (New York, N.Y.) 19325113 2009 Mar 27
Methods for measuring the thermodynamic stability of membrane proteins. Hong, Heedeok; Joh, Nathan H; Bowie, James U; Tamm, Lukas K Methods in enzymology 19289208 2009
Postnatal expression of V2 vasopressin receptor splice variants in the rat cerebellum. Vargas, Karina J; Sarmiento, Jose M; Ehrenfeld, Pamela; Anazco, Carolina C; Villanueva, Carolina I; Carmona, Pamela L; Brenet, Marianne; Navarro, Javier; Muller-Esterl, Werner; Gonzalez, Carlos B Differentiation; research in biological diversity 19281786 2009 Apr
Bicelles: A natural 'molecular goniometer' for structural, dynamical and topological studies of molecules in membranes. Diller, Anna; Loudet, Cecile; Aussenac, Fabien; Raffard, Gerard; Fournier, Sylvie; Laguerre, Michel; Grelard, Axelle; Opella, Stanley J; Marassi, Francesca M; Dufourc, Erick J Biochimie 19248817 2009 Jun
LCP-FRAP Assay for Pre-Screening Membrane Proteins for in Meso Crystallization. Cherezov, Vadim; Liu, Jeffrey; Griffith, Mark; Hanson, Michael A; Stevens, Raymond C Crystal growth & design 19234616 2008
Structure of the ligand-binding domain of the EphB2 receptor at 2 A resolution. Goldgur, Yehuda; Paavilainen, Sari; Nikolov, Dimitar; Himanen, J P Acta crystallographica. Section F, Structural biology and crystallization communications 19193989 2009 Feb 1
Characterization of the peroxidase mechanism upon reaction of prostacyclin synthase with peracetic acid. Identification of a tyrosyl radical intermediate. Yeh, Hui-Chun; Gerfen, Gary J; Wang, Jinn-Shyan; Tsai, Ah-Lim; Wang, Lee-Ho Biochemistry 19187034 2009 Feb 10
Backbone structure of a small helical integral membrane protein: A unique structural characterization. Page, Richard C; Lee, Sangwon; Moore, Jacob D; Opella, Stanley J; Cross, Timothy A Protein science : a publication of the Protein Society 19177358 2009 Jan
Towards the total chemical synthesis of integral membrane proteins: a general method for the synthesis of hydrophobic peptide-thioester building blocks. Johnson, Erik C B; Kent, Stephen B H Tetrahedron letters 19177172 2007 Mar 5
Genetic selection system for improving recombinant membrane protein expression in E. coli. Massey-Gendel, Elizabeth; Zhao, Anni; Boulting, Gabriella; Kim, Hye-Yeon; Balamotis, Michael A; Seligman, Len M; Nakamoto, Robert K; Bowie, James U Protein science : a publication of the Protein Society 19165721 2009 Feb
Discovery of new GPCR biology: one receptor structure at a time. Hanson, Michael A; Stevens, Raymond C Structure (London, England : 1993) 19141277 2009 Jan 14
An oxyferrous heme/protein-based radical intermediate is catalytically competent in the catalase reaction of Mycobacterium tuberculosis catalase-peroxidase (KatG). Suarez, Javier; Ranguelova, Kalina; Jarzecki, Andrzej A; Manzerova, Julia; Krymov, Vladimir; Zhao, Xiangbo; Yu, Shengwei; Metlitsky, Leonid; Gerfen, Gary J; Magliozzo, Richard S The Journal of biological chemistry 19139099 2009 Mar 13
X-ray structure of native scorpion toxin BmBKTx1 by racemic protein crystallography using direct methods. Mandal, Kalyaneswar; Pentelute, Brad L; Tereshko, Valentina; Kossiakoff, Anthony A; Kent, Stephen B H Journal of the American Chemical Society 19133782 2009 Feb 4
Proton-detected solid-state NMR spectroscopy of natural-abundance peptide and protein pharmaceuticals. Zhou, Donghua H; Shah, Gautam; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad M Angewandte Chemie (International ed. in English) 19130513 2009
Clogging the periplasmic pathway in LacY. Nie, Yiling; Zhou, Yonggang; Kaback, H Ronald Biochemistry 19128028 2009 Feb 3
Distinct effects of tafazzin deletion in differentiated and undifferentiated mitochondria. Acehan, Devrim; Khuchua, Zaza; Houtkooper, Riekelt H; Malhotra, Ashim; Kaufman, Johanna; Vaz, Frederic M; Ren, Mindong; Rockman, Howard A; Stokes, David L; Schlame, Michael Mitochondrion 19114128 2009 Apr
Nucleotide dependent packing differences in helical crystals of the ABC transporter MsbA. Ward, Andrew; Mulligan, Sheila; Carragher, Bridget; Chang, Geoffrey; Milligan, Ronald A Journal of structural biology 19114108 2009 Mar
Crystallizing membrane proteins for structure determination: use of lipidic mesophases. Caffrey, Martin Annual review of biophysics 19086821 2009
Selecting optimum eukaryotic integral membrane proteins for structure determination by rapid expression and solubilization screening. Li, Min; Hays, Franklin A; Roe-Zurz, Zygy; Vuong, Linda; Kelly, Libusha; Ho, Chi-Min; Robbins, Renee M; Pieper, Ursula; O'Connell 3rd, Joseph D; Miercke, Larry J W; Giacomini, Kathleen M; Sali, Andrej; Stroud, Robert M Journal of molecular biology 19061901 2009 Jan 23
Adenovirus mediated expression "in vivo" of the chemokine receptor CXCR1. Sarmiento, J; Kypreos, K E; Prado, G N; Suetomi, K; Stanzel, C; Maxwell, C; Shumate, D; Tandang-Silvas, M R; Rajarathnam, K; Navarro, J Journal of structural and functional genomics 19052917 2009 Mar
Ratiocinative screen of eukaryotic integral membrane protein expression and solubilization for structure determination. Hays, Franklin A; Roe-Zurz, Zygy; Li, Min; Kelly, Libusha; Gruswitz, Franz; Sali, Andrej; Stroud, Robert M Journal of structural and functional genomics 19031011 2009 Mar
HOLLOW: generating accurate representations of channel and interior surfaces in molecular structures. Ho, Bosco K; Gruswitz, Franz BMC structural biology 19014592 2008
High-throughput biotinylation of proteins. Kay, Brian K; Thai, Sang; Volgina, Veronica V Methods in molecular biology (Clifton, N.J.) 18988027 2009
Structural insights into G-protein-coupled receptor activation. Weis, William I; Kobilka, Brian K Current opinion in structural biology 18957321 2008 Dec
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist. Jaakola, Veli-Pekka; Griffith, Mark T; Hanson, Michael A; Cherezov, Vadim; Chien, Ellen Y T; Lane, J Robert; Ijzerman, Adriaan P; Stevens, Raymond C Science (New York, N.Y.) 18832607 2008 Nov 21
Simple host-guest chemistry to modulate the process of concentration and crystallization of membrane proteins by detergent capture in a microfluidic device. Li, Liang; Nachtergaele, Sigrid; Seddon, Annela M; Tereshko, Valentina; Ponomarenko, Nina; Ismagilov, Rustem F Journal of the American Chemical Society 18831551 2008 Oct 29
Orientation and structure of the Ndc80 complex on the microtubule lattice. Wilson-Kubalek, Elizabeth M; Cheeseman, Iain M; Yoshioka, Craig; Desai, Arshad; Milligan, Ronald A The Journal of cell biology 18794333 2008 Sep 22
Insights into the mode of action of a putative zinc transporter CzrB in Thermus thermophilus. Cherezov, Vadim; Hofer, Nicole; Szebenyi, Doletha M E; Kolaj, Olga; Wall, J Gerard; Gillilan, Richard; Srinivasan, Vasundara; Jaroniec, Christopher P; Caffrey, Martin Structure (London, England : 1993) 18786400 2008 Sep 10
Crystal structure of bovine mitochondrial factor B at 0.96-A resolution. Lee, John K; Belogrudov, Grigory I; Stroud, Robert M Proceedings of the National Academy of Sciences of the United States of America 18768789 2008 Sep 9
Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Hiller, Sebastian; Garces, Robert G; Malia, Thomas J; Orekhov, Vladislav Y; Colombini, Marco; Wagner, Gerhard Science (New York, N.Y.) 18755977 2008 Aug 29
Estimation of relative order tensors, and reconstruction of vectors in space using unassigned RDC data and its application. Miao, Xijiang; Mukhopadhyay, Rishi; Valafar, Homayoun Journal of magnetic resonance (San Diego, Calif. : 1997) 18692422 2008 Oct
Structural biology. Symmetric transporters for asymmetric transport. Karpowich, Nathan K; Wang, Da-Neng Science (New York, N.Y.) 18687947 2008 Aug 8
Rapid analysis of organic compounds by proton-detected heteronuclear correlation NMR spectroscopy with 40 kHz magic-angle spinning. Zhou, Donghua H; Rienstra, Chad M Angewandte Chemie (International ed. in English) 18683840 2008
Correlation of inhibitor effects on enzyme activity and thermal stability for the integral membrane protein fatty acid amide hydrolase. Slaymaker, Ian M; Bracey, Michael; Mileni, Mauro; Garfunkle, Joie; Cravatt, Benjamin F; Boger, Dale L; Stevens, Raymond C Bioorganic & medicinal chemistry letters 18644727 2008 Nov 15
X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers. Pentelute, Brad L; Gates, Zachary P; Tereshko, Valentina; Dashnau, Jennifer L; Vanderkooi, Jane M; Kossiakoff, Anthony A; Kent, Stephen B H Journal of the American Chemical Society 18598029 2008 Jul 30
Mirror image forms of snow flea antifreeze protein prepared by total chemical synthesis have identical antifreeze activities. Pentelute, Brad L; Gates, Zachary P; Dashnau, Jennifer L; Vanderkooi, Jane M; Kent, Stephen B H Journal of the American Chemical Society 18598026 2008 Jul 30
Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments. Asmar-Rovira, Guillermo A; Asseo-Garcia, Aloysha M; Quesada, Orestes; Hanson, Michael A; Cheng, Anchi; Nogueras, Carlos; Lasalde-Dominicci, Jose A; Stevens, Raymond C The Journal of membrane biology 18581036 2008 May
Glycotripod amphiphiles for solubilization and stabilization of a membrane-protein superassembly: importance of branching in the hydrophilic portion. Chae, Pil S; Wander, Marc J; Bowling, Aaron P; Laible, Philip D; Gellman, Samuel H Chembiochem : a European journal of chemical biology 18576450 2008 Jul 21
Protonation and sugar binding to LacY. Smirnova, Irina N; Kasho, Vladimir; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 18567672 2008 Jul 1
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor. Hanson, Michael A; Cherezov, Vadim; Griffith, Mark T; Roth, Christopher B; Jaakola, Veli-Pekka; Chien, Ellen Y T; Velasquez, Jeffrey; Kuhn, Peter; Stevens, Raymond C Structure (London, England : 1993) 18547522 2008 Jun
Protein crystallization in restricted geometry: advancing old ideas for modern times in structural proteomics. Ng, Joseph D; Stevens, Raymond C; Kuhn, Peter Methods in molecular biology (Clifton, N.J.) 18542876 2008
Orientation of the Escherichia coli outer membrane protein OmpX in phospholipid bilayer membranes determined by solid-State NMR. Mahalakshmi, Radhakrishnan; Marassi, Francesca M Biochemistry 18512961 2008 Jun 24
Crystal structure of the aquaglyceroporin PfAQP from the malarial parasite Plasmodium falciparum. Newby, Zachary E R; O'Connell 3rd, Joseph; Robles-Colmenares, Yaneth; Khademi, Shahram; Miercke, Larry J; Stroud, Robert M Nature structural & molecular biology 18500352 2008 Jun
Solid-state NMR spectroscopy of a membrane protein in biphenyl phospholipid bicelles with the bilayer normal parallel to the magnetic field. Park, Sang Ho; Loudet, Cecile; Marassi, Francesca M; Dufourc, Erick J; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 18492613 2008 Jul
The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway. Nie, Yiling; Sabetfard, Frances E; Kaback, H Ronald Journal of molecular biology 18485365 2008 Jun 13
Microscale NMR screening of new detergents for membrane protein structural biology. Zhang, Qinghai; Horst, Reto; Geralt, Michael; Ma, Xingquan; Hong, Wen-Xu; Finn, M G; Stevens, Raymond C; Wuthrich, Kurt Journal of the American Chemical Society 18479092 2008 Jun 11
GFP-based optimization scheme for the overexpression and purification of eukaryotic membrane proteins in Saccharomyces cerevisiae. Drew, David; Newstead, Simon; Sonoda, Yo; Kim, Hyun; von Heijne, Gunnar; Iwata, So Nature protocols 18451787 2008
Microscale fluorescent thermal stability assay for membrane proteins. Alexandrov, Alexander I; Mileni, Mauro; Chien, Ellen Y T; Hanson, Michael A; Stevens, Raymond C Structure (London, England : 1993) 18334210 2008 Mar
Rapid classification of protein structure models using unassigned backbone RDCs and probability density profile analysis (PDPA). Bansal, Sonal; Miao, Xijiang; Adams, Michael W W; Prestegard, James H; Valafar, Homayoun Journal of magnetic resonance (San Diego, Calif. : 1997) 18321742 2008 May
Opening and closing of the periplasmic gate in lactose permease. Zhou, Yonggang; Guan, Lan; Freites, J Alfredo; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 18319336 2008 Mar 11
Expression and function of the rat vesicular monoamine transporter 2. Adam, Yoav; Edwards, Robert H; Schuldiner, Shimon American journal of physiology. Cell physiology 18287335 2008 Apr
High-performance solvent suppression for proton detected solid-state NMR. Zhou, Donghua H; Rienstra, Chad M Journal of magnetic resonance (San Diego, Calif. : 1997) 18276175 2008 May
Shiftless nuclear magnetic resonance spectroscopy. Wu, Chin H; Opella, Stanley J The Journal of chemical physics 18266429 2008 Feb 7
REDCRAFT: a tool for simultaneous characterization of protein backbone structure and motion from RDC data. Bryson, Michael; Tian, Fang; Prestegard, James H; Valafar, Homayoun Journal of magnetic resonance (San Diego, Calif. : 1997) 18258464 2008 Apr
Chemical shift assignment of the transmembrane helices of DsbB, a 20-kDa integral membrane enzyme, by 3D magic-angle spinning NMR spectroscopy. Li, Ying; Berthold, Deborah A; Gennis, Robert B; Rienstra, Chad M Protein science : a publication of the Protein Society 18227427 2008 Feb
Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure. Roth, Christopher B; Hanson, Michael A; Stevens, Raymond C Journal of molecular biology 18222471 2008 Mar 7
In situ X-ray analysis of protein crystals in low-birefringent and X-ray transmissive plastic microchannels. Ng, Joseph D; Clark, Peter J; Stevens, Raymond C; Kuhn, Peter Acta crystallographica. Section D, Biological crystallography 18219119 2008 Feb
New G-protein-coupled receptor crystal structures: insights and limitations. Kobilka, Brian; Schertler, Gebhard F X Trends in pharmacological sciences 18194818 2008 Feb
Tailoring 13C labeling for triple-resonance solid-state NMR experiments on aligned samples of proteins. Sinha, Neeraj; Filipp, Fabian V; Jairam, Lena; Park, Sang Ho; Bradley, Joel; Opella, Stanley J Magnetic resonance in chemistry : MRC 18157808 2007 Dec
In meso crystal structure and docking simulations suggest an alternative proteoglycan binding site in the OpcA outer membrane adhesin. Cherezov, Vadim; Liu, Wei; Derrick, Jeremy P; Luan, Binquan; Aksimentiev, Aleksei; Katritch, Vsevolod; Caffrey, Martin Proteins 18076035 2008 Apr
Crystal polymorphism of protein GB1 examined by solid-state NMR spectroscopy and X-ray diffraction. Schmidt, Heather L Frericks; Sperling, Lindsay J; Gao, Yi Gui; Wylie, Benjamin J; Boettcher, John M; Wilson, Scott R; Rienstra, Chad M The journal of physical chemistry. B 18052145 2007 Dec 27
X-ray structure of EmrE supports dual topology model. Chen, Yen-Ju; Pornillos, Owen; Lieu, Samantha; Ma, Che; Chen, Andy P; Chang, Geoffrey Proceedings of the National Academy of Sciences of the United States of America 18024586 2007 Nov 27
Flexibility in the ABC transporter MsbA: Alternating access with a twist. Ward, Andrew; Reyes, Christopher L; Yu, Jodie; Roth, Christopher B; Chang, Geoffrey Proceedings of the National Academy of Sciences of the United States of America 18024585 2007 Nov 27
High-yield expression and purification of isotopically labeled cytochrome P450 monooxygenases for solid-state NMR spectroscopy. Rupasinghe, Sanjeewa G; Duan, Hui; Frericks Schmidt, Heather L; Berthold, Deborah A; Rienstra, Chad M; Schuler, Mary A Biochimica et biophysica acta 18005930 2007 Dec
Proton-detected separated local field spectroscopy. Wu, Chin H; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 17981481 2008 Jan
TARP auxiliary subunits switch AMPA receptor antagonists into partial agonists. Menuz, Karen; Stroud, Robert M; Nicoll, Roger A; Hays, Franklin A Science (New York, N.Y.) 17975069 2007 Nov 2
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Cherezov, Vadim; Rosenbaum, Daniel M; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Kuhn, Peter; Weis, William I; Kobilka, Brian K; Stevens, Raymond C Science (New York, N.Y.) 17962520 2007 Nov 23
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Rosenbaum, Daniel M; Cherezov, Vadim; Hanson, Michael A; Rasmussen, Soren G F; Thian, Foon Sun; Kobilka, Tong Sun; Choi, Hee-Jung; Yao, Xiao-Jie; Weis, William I; Stevens, Raymond C; Kobilka, Brian K Science (New York, N.Y.) 17962519 2007 Nov 23
NMR and mutagenesis of human copper transporter 1 (hCtr1) show that Cys-189 is required for correct folding and dimerization. Lee, Sangwon; Howell, Stephen B; Opella, Stanley J Biochimica et biophysica acta 17959139 2007 Dec
Membrane protein crystallization in lipidic mesophases. A mechanism study using X-ray microdiffraction. Cherezov, Vadim; Caffrey, Martin Faraday discussions 17955811 2007
A high-throughput strategy to screen 2D crystallization trials of membrane proteins. Vink, Martin; Derr, Kd; Love, James; Stokes, David L; Ubarretxena-Belandia, Iban Journal of structural biology 17951070 2007 Dec
Bicelle samples for solid-state NMR of membrane proteins. De Angelis, Anna A; Opella, Stanley J Nature protocols 17947974 2007
Structure refinement of the OpcA adhesin using molecular dynamics. Luan, Binquan; Caffrey, Martin; Aksimentiev, Aleksei Biophysical journal 17938421 2007 Nov 1
Cell-cell signaling via Eph receptors and ephrins. Himanen, Juha-Pekka; Saha, Nayanendu; Nikolov, Dimitar B Current opinion in cell biology 17928214 2007 Oct
Sugar binding induces an outward facing conformation of LacY. Smirnova, Irina; Kasho, Vladimir; Choe, Jun-Yong; Altenbach, Christian; Hubbell, Wayne L; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 17925435 2007 Oct 16
Site-directed alkylation of LacY: effect of the proton electrochemical gradient. Nie, Yiling; Ermolova, Natalia; Kaback, H Ronald Journal of molecular biology 17920075 2007 Nov 23
NMR structural studies of the bacterial outer membrane protein OmpX in oriented lipid bilayer membranes. Mahalakshmi, Radhakrishnan; Franzin, Carla M; Choi, Jungyuen; Marassi, Francesca M Biochimica et biophysica acta 17916325 2007 Dec
Transmembrane domain of myelin protein zero can form dimers: possible implications for myelin construction. Plotkowski, Megan L; Kim, Sanguk; Phillips, Martin L; Partridge, Anthony W; Deber, Charles M; Bowie, James U Biochemistry 17915947 2007 Oct 30
Solid-state protein-structure determination with proton-detected triple-resonance 3D magic-angle-spinning NMR spectroscopy. Zhou, Donghua H; Shea, John J; Nieuwkoop, Andrew J; Franks, W Trent; Wylie, Benjamin J; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad M Angewandte Chemie (International ed. in English) 17907259 2007
Structural determination of wild-type lactose permease. Guan, Lan; Mirza, Osman; Verner, Gillian; Iwata, So; Kaback, H Ronald Proceedings of the National Academy of Sciences of the United States of America 17881559 2007 Sep 25
High resolution 1H NMR of a lipid cubic phase using a solution NMR probe. Boyle-Roden, E; Hoefer, N; Dey, K K; Grandinetti, P J; Caffrey, M Journal of magnetic resonance (San Diego, Calif. : 1997) 17855136 2007 Nov
Proton-detected solid-state NMR spectroscopy of fully protonated proteins at 40 kHz magic-angle spinning. Zhou, Donghua H; Shah, Gautam; Cormos, Mircea; Mullen, Charles; Sandoz, Dennis; Rienstra, Chad M Journal of the American Chemical Society 17725352 2007 Sep 26
Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression. Hanson, Michael A; Brooun, Alexei; Baker, Kent A; Jaakola, Veli-Pekka; Roth, Chris; Chien, Ellen Y T; Alexandrov, Alexander; Velasquez, Jeffrey; Davis, Leila; Griffith, Mark; Moy, Kin; Ganser-Pornillos, Barbie K; Hua, Yuanzi; Kuhn, Peter; Ellis, Sam; Yeag Protein expression and purification 17723307 2007 Nov
An efficient (1)H/(31)P double-resonance solid-state NMR probe that utilizes a scroll coil. Grant, Christopher V; Sit, Siu-Ling; De Angelis, Anna A; Khuong, Kelli S; Wu, Chin H; Plesniak, Leigh A; Opella, Stanley J Journal of magnetic resonance (San Diego, Calif. : 1997) 17719813 2007 Oct
Modular total chemical synthesis of a human immunodeficiency virus type 1 protease. Johnson, Erik C B; Malito, Enrico; Shen, Yuequan; Rich, Dan; Tang, Wei-Jen; Kent, Stephen B H Journal of the American Chemical Society 17705484 2007 Sep 19
Designing facial amphiphiles for the stabilization of integral membrane proteins. Zhang, Qinghai; Ma, Xingquan; Ward, Andrew; Hong, Wen-Xu; Jaakola, Veli-Pekka; Stevens, Raymond C; Finn, M G; Chang, Geoffrey Angewandte Chemie (International ed. in English) 17691085 2007
LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Zhou, Zheng; Zhen, Juan; Karpowich, Nathan K; Goetz, Regina M; Law, Christopher J; Reith, Maarten E A; Wang, Da-Neng Science (New York, N.Y.) 17690258 2007 Sep 7
Crystallization and preliminary X-ray diffraction analysis of a soluble domain of the putative zinc transporter CzrB from Thermus thermophilus. Hofer, Nicole; Kolaj, Olga; Li, Hui; Cherezov, Vadim; Gillilan, Richard; Wall, J Gerard; Caffrey, Martin Acta crystallographica. Section F, Structural biology and crystallization communications 17671365 2007 Aug 1
Total chemical synthesis and biophysical characterization of the minimal isoform of the KChIP2 potassium channel regulatory subunit. Rajagopal, Sudarshan; Kent, Stephen B H Protein science : a publication of the Protein Society 17660260 2007 Sep
When biochemistry meets structural biology: the cautionary tale of EmrE. Schuldiner, Shimon Trends in biochemical sciences 17452106 2007 Jun
Crystal structure of the human ephrin-A5 ectodomain. Nikolov, Dimitar; Li, Chen; Lackmann, Martin; Jeffrey, Philip; Himanen, Juha Protein science : a publication of the Protein Society 17400922 2007 May
Using a multijunction microfluidic device to inject substrate into an array of preformed plugs without cross-contamination: comparing theory and experiments. Li, Liang; Boedicker, James Q; Ismagilov, Rustem F Analytical chemistry 17338503 2007 Apr 1
Kinetic analysis of the binding of monomeric and dimeric ephrins to Eph receptors: correlation to function in a growth cone collapse assay. Pabbisetty, Kumar B; Yue, Xin; Li, Chen; Himanen, Juha-Pekka; Zhou, Renping; Nikolov, Dimitar B; Hu, Longqin Protein science : a publication of the Protein Society 17322526 2007 Mar
Partial (13)C and (15)N chemical-shift assignments of the disulfide-bond-forming enzyme DsbB by 3D magic-angle spinning NMR spectroscopy. Li, Ying; Berthold, Deborah A; Frericks, Heather L; Gennis, Robert B; Rienstra, Chad M Chembiochem : a European journal of chemical biology 17285659 2007 Mar 5
NMR structural investigation of the mitochondrial outer membrane protein VDAC and its interaction with antiapoptotic Bcl-xL. Malia, Thomas J; Wagner, Gerhard Biochemistry 17209561 2007 Jan 16
Nanoliter microfluidic hybrid method for simultaneous screening and optimization validated with crystallization of membrane proteins. Li, Liang; Mustafi, Debarshi; Fu, Qiang; Tereshko, Valentina; Chen, Delai L; Tice, Joshua D; Ismagilov, Rustem F Proceedings of the National Academy of Sciences of the United States of America 17159147 2006 Dec 19
Exploratory synthesis of peptide-alpha-thioester segments spanning the polypeptide sequence of the delta-opioid receptor, a G protein-coupled receptor. Johnson, Erik C B; Kent, Stephen B H Biopolymers 17120238 2007
Reactions in droplets in microfluidic channels. Song, Helen; Chen, Delai L; Ismagilov, Rustem F Angewandte Chemie (International ed. in English) 17086584 2006 Nov 13
Ultrafast hydration dynamics in the lipidic cubic phase: Discrete water structures in nanochannels. Kim, Jongjoo; Lu, Wenyun; Qiu, Weihong; Wang, Lijuan; Caffrey, Martin; Zhong, Dongping The journal of physical chemistry. B 17064169 2006 Nov 2
Controlling the passage of light through metal microchannels by nanocoatings of phospholipids. Teeters-Kennedy, Shannon M; Rodriguez, Kenneth R; Rogers, Trisha M; Zomchek, Keith A; Williams, Shaun M; Sudnitsyn, Alexandra; Carter, Lauren; Cherezov, Vadim; Caffrey, Martin; Coe, James V The journal of physical chemistry. B 17064131 2006 Nov 2
In meso structure of the cobalamin transporter, BtuB, at 1.95 A resolution. Cherezov, V; Yamashita, E; Liu, W; Zhalnina, M; Cramer, W A; Caffrey, M Journal of molecular biology 17028020 2006 Dec 8
Interactions of tryptophan, tryptophan peptides, and tryptophan alkyl esters at curved membrane interfaces. Liu, Wei; Caffrey, Martin Biochemistry 17002272 2006 Oct 3
Structure determination of a membrane protein with two trans-membrane helices in aligned phospholipid bicelles by solid-state NMR spectroscopy. De Angelis, Anna A; Howell, Stanley C; Nevzorov, Alexander A; Opella, Stanley J Journal of the American Chemical Society 16967977 2006 Sep 20
Identification of individual protein-ligand NOEs in the limit of intermediate exchange. Reibarkh, Mikhail; Malia, Thomas J; Hopkins, Brian T; Wagner, Gerhard Journal of biomolecular NMR 16964534 2006 Sep
Magic-angle spinning solid-state NMR of a 144 kDa membrane protein complex: E. coli cytochrome bo3 oxidase. Frericks, Heather L; Zhou, Donghua H; Yap, Lai Lai; Gennis, Robert B; Rienstra, Chad M Journal of biomolecular NMR 16964530 2006 Sep
Production of arrays of chemically distinct nanolitre plugs via repeated splitting in microfluidic devices. Adamson, David N; Mustafi, Debarshi; Zhang, John X J; Zheng, Bo; Ismagilov, Rustem F Lab on a chip 16929397 2006 Sep
High-resolution NMR spectroscopy of a GPCR in aligned bicelles. Park, Sang Ho; Prytulla, Stefan; De Angelis, Anna A; Brown, Jonathan Miles; Kiefer, Hans; Opella, Stanley J Journal of the American Chemical Society 16756269 2006 Jun 14
Microfluidic cartridges preloaded with nanoliter plugs of reagents: an alternative to 96-well plates for screening. Chen, Delai L; Ismagilov, Rustem F Current opinion in chemical biology 16677848 2006 Jun
Room to move: crystallizing membrane proteins in swollen lipidic mesophases. Cherezov, Vadim; Clogston, Jeffrey; Papiz, Miroslav Z; Caffrey, Martin Journal of molecular biology. 16490208 2006 Apr 14
NMR distinction of single- and multiple-mode binding of small-molecule protein ligands. Reibarkh, Mikhail; Malia, Thomas J; Wagner, Gerhard Journal of the American Chemical Society 16478139 2006 Feb 22
An architectural framework that may lie at the core of the postsynaptic density. Baron, Marisa K; Boeckers, Tobias M; Vaida, Bianca; Faham, Salem; Gingery, Mari; Sawaya, Michael R; Salyer, Danielle; Gundelfinger, Eckart D; Bowie, James U Science (New York, N.Y.) 16439662 2006 Jan 27
X-ray structure of the EmrE multidrug transporter in complex with a substrate. Pornillos, Owen; Chen, Yen-Ju; Chen, Andy P; Chang, Geoffrey Science (New York, N.Y.) 16373573 2005 Dec 23
The Membrane Protein Data Bank. Raman, P; Cherezov, V; Caffrey, M Cellular and molecular life sciences : CMLS 16314922 2006 Jan
Characterization of bacterial drug antiporters homologous to mammalian neurotransmitter transporters. Vardy, Eyal; Steiner-Mordoch, Sonia; Schuldiner, Shimon Journal of bacteriology. 16237035 2005 Nov
The past, present and future of cell-free protein synthesis. Katzen, Federico; Chang, Geoffrey; Kudlicki, Wieslaw Trends in biotechnology. 15734558 2005 Mar
Synthesis of fluorescein labeled 7-methylguanosinemonophosphate. Natarajan, Amarnath; Moerke, Nathan; Fan, Yun-Hua; Chen, Han; Christ, William J; Wagner, Gerhard; Halperin, Jose A Bioorganic & medicinal chemistry letters 15109672 2004 May 17

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