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Funded Research

Membrane Protein Productionfor Structure Determination(R01)
RFA-RM-09-012
PI NameInstitution NameTitle
BETENBAUGH, MICHAEL JJOHNS HOPKINS UNIVERSITYEvolving Membrane Proteins for High Level Expression in Modified Mammalian Cells
CARRAGHER, BRIDGET OLIVIASCRIPPS RESEARCH INSTITUTEA Helical Crystallization Pipeline for Membrane Protein Structure by TEM
CHOE, SENYONSALK INSTITUTE FOR BIOLOGICAL STUDIESCell-Free Expression of Human Integral Membrane Proteins for Structural Studies
DELUCAS, LAWRENCE JUNIVERSITY OF ALABAMA AT BIRMINGHAMProduction & Crystallization of Membrane Protein for 3D Structure
FROMME, PETRA.ARIZONA STATE UNIVERSITY-TEMPE CAMPUSFemtosecond Nano-Crystallography of Membrane Proteins
GENNIS, ROBERT BUNIVERSITY OF ILLINOIS URBANA-CHAMPAIGNUsing Extreme Thermophiles for the Homologous Expression of Membrane Proteins
GUAN, LANTEXAS TECH UNIVERSITY HEALTH SCIS CENTERNovel Capture Reagents for Membrane Protein Structure Determination
IVERSON, T MVANDERBILT UNIVERSITYStabilization of Membrane Protein Signaling Complexes
MAYNARD, JENNIFER AUNIVERSITY OF TEXAS AUSTINEngineered Antibody Fragments for Co-Crystallization with Signal Peptide Peptidase
RAMAMOORTHY, AYYALUSAMYUNIVERSITY OF MICHIGAN AT ANN ARBORRapid and Efficient Production of Functional Cytochrome P450 Enzymatic Complexes
STOKES, DAVID LNEW YORK STRUCTURAL BIOLOGY CENTERHigh Throughput Pipeline for Electron Crystallography
WOYCHIK, NANCY ANNUNIV OF MED/DENT NJ-R W JOHNSON MED SCHMembrane Protein Production Using the Yeast SPP System

 

Membrane Protein Production and Structure Determination (R01)
(RFA-RM-07-003)
PI NameInstitution NameTitle
ALLEN, PAUL D.BRIGHAM AND WOMEN'S HOSPITALIntegral Membrane Protein Overexpression Using Organ Bioreactors
BOWIE, JAMES U.UNIVERSITY OF CALIFORNIA LOS ANGELESImproving Membrane Protein Crystallization
DELUCAS, LAWRENCEUNIVERSITY OF ALABAMA AT BIRMINGHANInnovative Methods for Membrane Protein Crystallization
NAVARRO, JAVIER V.UNIVERSITY OF TEXAS MEDICAL BR GALVESTONStructural Biology of G Protein-Coupled Receptors
SANDERS, CHARLES R.VANDERBILT UNIVERSITY.Overcoming the Barriers to Structural Analysis of GPCRs
SPILLER, BENJAMIN W.VANDERBILT UNIVERSITYStructural Studies of Voltage Gating in Voltage-Gated Sodium Channels
STOKES, DAVID L.NEW YORK STRUCTURAL BIOLOGY CENTERMembrane Protein Structure by Electron Crystallography

 

Membrane Protein Production and Structure Determination (R01- R21- P01)
RFA-RM-04-026
PI NameInstitution NameTitle
BOWIE, JAMES UUNIVERSITY OF CALIFORNIA LOS ANGELESGeneration of Membrane Protein Production Strains
CAFFREY, MARTIN D.UNIVERSITY OF LIMERICK RESEARCH FDNMembrane Proteins. Crystallogenesis and X-ray Structure
GERFEN, GARY J.YESHIVA UNIVERSITYProton Crystallography of Membrane Proteins Using High Frequency ENDOR
GROS, PHILIPPEMC GILL UNIVERSITYExpression of ABC Transporters in Pichia Pastoris
HIMANEN, JUHA PSLOAN-KETTERING INSTITUTE FOR CANCER RESExpression and Structural Study of Eph Receptor Kinases
HUNT, JOHN FCOLUMBIA UNIV NEW YORK MORNINGSIDEA Chemical Genetics Approach to Improved IMP Expression in E. Coli
ISMAGILOV, RUSTEM FUNIVERSITY OF CHICAGOEnabling Nanoliter Membrane Protein Crystallization
KENIS, PAUL JUNIVERSITY OF ILLINOIS URBANA-CHAMPAIGNInnovative Methods for Membrane Protein Crystallization
KENT, STEPHEN B.HUNIVERSITY OF CHICAGOA Systematic Approach to the Chemical Synthesis of G-Protein Coupled Receptors
KOBILKA, BRIAN KSTANFORD UNIVERSITYChimeric Proteins to Enhance Crystal Formation of G Protein Coupled Receptors
LAIBLE, PHILIP DUNIVERSITY OF CHICAGOReagents: Promote Membrane Protein Stability and Crystallization
LOLL, PATRICK JDREXEL UNIVERSITY COLLEGE OF MEDICINEMapping the Crystallization Slot for Membrane Proteins
MARASSI, FRANCESCA MBURNHAM INSTITUTEStructure of a Beta Barrel Membrane Protein in Lipid Bilayer Membranes
MILLIGAN, RONALD ASCRIPPS RESEARCH INSTITUTEELECTRON MICROSCOPY OF MEMBRANE PROTEINS
OPELLA, STANLEY JUNIVERSITY OF CALIFORNIA SAN DIEGOMembrane Protein Structures in Phospholipid Bilayers by Solid State NMR
RIENSTRA, CHAD MUNIVERSITY OF ILLINOIS URBANA-CHAMPAIGNStructure and Function of Membrane Protein Complexes by Solid State NMR
WAGNER, GERHARDHARVARD UNIVERSITY (MEDICAL SCHOOL)Expression, Labeling and NMR Structure Determination of Integral Membrane Protein
WANG, DA-NENGNEW YORK UNIVERSITY SCHOOL OF MEDICINECrystallization of Neurotransmitter Transporter Homologs
WIENER, MICHAEL C.UNIVERSITY OF VIRGINIA CHARLOTTESVILLEImproved Methods for Membrane Protein Crystallization

 

Centers for Innovation in Membrane Protein Production for Structure Determination (P50)
RFA-RM-08-019
PI NameInstitution NameTitle
CRAMER, WILLIAM A.PURDUE UNIVERSITY WEST LAFAYETTEImproving Rate/Quality Limitations in Membrane Protein Structure Determination
STEVENS, RAYMOND C.SCRIPPS RESEARCH INSTITUTEJoint Center for Integral Membrane Protein Technologies-Complexes (JCIMPT-Complexes)
STROUD, ROBERT M.UNIVERSITY OF CALIFORNIA SAN FRANCISCOMembrane Protein Expression Center (MPEC)

 

Centers for Innovation in Membrane Protein Production (P50)
RFA-RM-04-009
PI NameInstitution NameTitle
STEVENS, RAYMOND CSCRIPPS RESEARCH INSTITUTEJCSG Center for Innovative Membrane Protein Technologies
STROUD, ROBERT MUNIVERSITY OF CALIFORNIA SAN FRANCISCOCenter for Innovation in Membrane Protein Production

This page last reviewed on January 17, 2024