Skip to main content
NIH Director's Transformative Research Award logo.

Application & Award Guide

  1. Eligibilitynot completed
  2. Application Processnot completed
  3. After Submissionnot completed
  4. Award Managementnot completed


The information in these pages are meant to provide general guidance. Instructions and procedures outlined in the funding opportunity, SF424 Application Guide, and NIH Grants Policy Statement take precedence over any information provided and should be referred to for complete and comprehensive directions.

Learn more about applying for and managing an New Innovator Award. This guide contains information on:

SF424 (R&R) Application Guide

The SF424 (R&R) Application Guide provides comprehensive guidance on how to submit applications to NIH, the Centers for Disease Control and Prevention, the Food and Drug Administration, and the Agency for Healthcare Research and Quality.

Use the SF424 (R&R) version outlined in the funding opportunity, and follow the Research Instructions (R).

The funding opportunity provides all the information needed to successfully assemble your application and will tell you when to refer to the SF424 (R&R) Application Guide for more detailed instructions. It will also tell you when to deviate from the SF424 (R&R) Application Guide. Instructions in the funding opportunity supersede instructions from the SF424 (R&R) Application Guide. Failure to comply with the instructions and requirements outlined in the funding opportunity may result in your application being administratively withdrawn for non-compliance.



More questions? Contact us at


This page last reviewed on March 26, 2024