Funded Research

The Epigenomics program has transitioned from Common Fund support. For more information, please visit https://commonfund.nih.gov/epigenomics.

Please note that since the Epigenomics program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis.

**NIH Support for Conferences and Scientific Meetings (Parent R13/U13) PA-13-347**
PI Name	Institution Name	Title
STAMATOYANNOPOULOS, JOHN A (contact) MILOSAVLJEVIC, ALEKSANDAR	UNIVERSITY OF WASHINGTON	Epigenomics 2015: A Roadmap to the Living Genome
WOODLAND, DAVID L.	KEYSTONE SYMPOSIA	DNA Methylation
WOODLAND, DAVID L.	KEYSTONE SYMPOSIA	Epigenomics

**Computational Analyses Exploiting Reference Epigenomic Maps (R01) RFA-RM-14-001**
PI Name	Institution Name	Title
FUREY, TERRENCE S. (contact) SHEIKH, SHEHZAD Z.	UNIV OF NORTH CAROLINA CHAPEL HILL	Interpreting molecular role of DNA variants associated with Crohns Disease through integrative analysis of open chromatin, epigenome and transcriptome data in diverse and relevant tissues and cells
INCE, TAN A.	UNIVERSITY OF MIAMI	Computational and Biological Deconvolution of Epigenomic Datasets
JOHNSON, WILLIAM EVAN	BOSTON UNIVERSITY MEDICAL CAMPUS	Integrative analyses of reference epigenomic maps and applications
LI, ZHAOYU (contact) ASMANN, YAN W.	MAYO CLINIC JACKSONVILLE	Building the Foundation of Epigenomics Roadmaps
LIU, CHUNYU	UNIVERSITY OF ILLINOIS AT CHICAGO	Integrating epigenomic maps to predict regulatory functions of genetic variants
NOBLE, WILLIAM STAFFORD	UNIVERSITY OF WASHINGTON	Machine learning methods to impute and annotate epigenomic maps
PRITCHARD, JONATHAN K	STANFORD UNIVERSITY	Computational methods for modeling lineage-specific gene regulation
REN, BING	LUDWIG INSTITUTE FOR CANCER RES LTD	Integrative Analysis of Haplotype-Resolved Human Epigenome Maps
WAGERS, AMY JO	HARVARD UNIVERSITY	Epigenomic drivers of human muscle progenitor cells in development and disease
WANG, TING	WASHINGTON UNIVERSITY	CHARTING THE EPIGENOMIC LANDSCAPE OF HUMAN TRANSPOSABLE ELEMENTS
XING, YI (contact) HOFFMANN, ALEXANDER	UNIVERSITY OF CALIFORNIA LOS ANGELES	Epigenomic control of RNA splicing

**Functional Epigenomics: Developing Tools and Technologies for Cell-type, Temporal, or Locus-specific Manipulation of the Epigenome (R01) RFA-RM-12-026**
PI Name	Institution Name	Title
BLANCAFORT, PILAR (contact) LISTER, RYAN	UNIVERSITY OF WESTERN AUSTRALIA	Precision engineering of DNA methylation patterns in the human genome
DURONIO, ROBERT J (contact) MATERA, A. GREGORY STRAHL, BRIAN D	UNIV OF NORTH CAROLINA CHAPEL HILL	Engineering histone genes to interrogate the epigenetic code in space and time
GERSBACH, CHARLES A (contact) CRAWFORD, GREGORY E	DUKE UNIVERSITY	Engineering Targeted Epigenetic Modifiers for Precise Control of Gene Regulation
KOIDE, SHOHEI	UNIVERSITY OF CHICAGO	Genetically encoded designer inhibitors for functional epigenomics
KUHLMAN, BRIAN A (contact) HAHN, KLAUS MICHAEL	UNIV OF NORTH CAROLINA CHAPEL HILL	Spatiotemporal Control of the Epigenome via Photoactivatable Nuclear Localization
LEE, JEANNIE T	MASSACHUSETTS GENERAL HOSP	The RNA-activation platform to treat X-linked disease in a locus-specific manner
LOMVARDAS, STAVROS (contact) BARNEA, GILAD	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Controlling epigenetic states and nuclear architecture in the brain
MEISSNER, ALEXANDER	HARVARD UNIVERSITY	Generation and characterization of tools for target-specific de novo DNA methylat
TASIC, BOSILJKA (contact) MADISEN, LINDA	ALLEN INSTITUTE FOR BRAIN SCIENCE	Temporal, cell type- and locus-specific epigenetic control in transgenic mice
WEISSMAN, JONATHAN S. (contact) LIM, WENDELL A QI, LEI STANLEY	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Harnessing CRISPR for Targeted and Inducible Epigenomic Reprogramming

**Epigenomics of Human Health and Disease (R01) RFA-RM-08-017**
PI Name	Institution Name	Title
BENNETT, DAVID A.	RUSH UNIVERSITY MEDICAL CENTER	Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences
COLEMAN, PAUL D.	SUN HEALTH RESEARCH INSTITUTE	DNA methylation in Alzheimer's disease and normally aged brain
CONNELLY, JESSICA J.	UNIVERSITY OF VIRGINIA CHARLOTTESVILLE	Epigenomics of Atherosclerosis
EINSTEIN, FRANCINE HUGHES (contact) GREALLY, JOHN MONTAGNA, CRISTINA	YESHIVA UNIVERSITY	Genome-wide DNA Methylation Profiles Associated with Abnormal Intrauterine Growth
FALLIN, MARGARET DANIELE (Contact) FEINBERG, ANDREW P.	JOHNS HOPKINS UNIVERSITY	Environment, The Perinatal Epigenome, and Risk for Autism and Related Disorders
GIBBONS, GARY HUGH	MOREHOUSE SCHOOL OF MEDICINE	Vascular Epigenome Dynamics in African-American Hypertensives
HUANG, TIM H.-M.	OHIO STATE UNIVERSITY	Epigenomics of Bisphenol A Exposure and Disease Risk
KOHWI-SHIGEMATSU, TERUMI	UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB	Determinants for genome-wide epigenomics in metastatic breast cancer
LIU, YONGMEI	WAKE FOREST UNIVERSITY HEALTH SCIENCES	Epigenome-Wide Association Study of DNA Methylation and Atherosclerosis
MELTZER, STEPHEN J.	JOHNS HOPKINS UNIVERSITY	The temporal epigenomic program of Barrett's neoplastic progression
MERBS, SHANNATH L.	JOHNS HOPKINS UNIVERSITY	Pangenomic Analysis of DNA Methylation Marks in Glaucoma and Macular Degeneration
MILL, JONATHAN	KING'S COLLEGE LONDON	A multi-faceted approach to epigenomic profiling in Alzheimer's disorder
OPHOFF, ROEL A.	UNIVERSITY OF CALIFORNIA LOS ANGELES	Epigenetics and disease: the role of DNA methylation in schizophrenia susceptibility
PETRONIS, ART	CENTRE FOR ADDICTION AND MENTAL HEALTH	DNA METHYLOME ANALYSIS IN BIPOLAR DISORDER
PFEIFER, GERD P.	CITY OF HOPE/BECKMAN RESEARCH INSTITUTE	Aging and the unstable epigenome
ROSEN, EVAN D.	BETH ISRAEL DEACONESS MEDICAL CENTER	Epigenomics of Human Insulin Resistance
SCHWARTZ, DAVID ALBERT (contact) COSGROVE, GREGORY P. YANG, IVANA VERONA	NATIONAL JEWISH HEALTH	Asthma: An Epidemic Caused by Epigenetics?
SULLIVAN, KATHLEEN E.	CHILDREN'S HOSPITAL OF PHILADELPHIA	Epigenomics of SLE
SUSZTAK, KATALIN (contact) GREALLY, JOHN	YESHIVA UNIVERSITY	Epigenetics Landscape of Chronic Kidney Disease
TYCKO, BENJAMIN (contact) MAYEUX, RICHARD	COLUMBIA UNIVERSITY HEALTH SCIENCES	Epigenomics of Alzheimer's Disease
YOKOMORI, KYOKO	UNIVERSITY OF CALIFORNIA IRVINE	Epigenomic Analysis of Facioscapulohumeral Muscular Dystrophy
YOUNG, RICHARD	WHITEHEAD INSTITUTE FOR BIOMEDICAL RES	Epigenomic Mapping in Human Tumor Stem Cells

**Reference Epigenome Mapping Centers (U01) RFA-RM-07-013**
PI Name	Institution Name	Title
BERNSTEIN, BRADLEY E (contact) MEISSNER, ALEXANDER	MASSACHUSETTS INSTITUTE OF TECHNOLOGY	Production sequencing of reference human epigenomes
COSTELLO, JOSEPH F (contact) MARRA, MARCO ANTONIO	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Integrated Epigenetic Maps of Human Embryonic and Adult Cells
REN, BING	LUDWIG INSTITUTE FOR CANCER RESEARCH	The San Diego Epigenome Center
STAMATOYANNOPOULOS, JOHN	UNIVERSITY OF WASHINGTON	Northwest Reference Epigenome Mapping Center

**Epigenomics Data Analysis and Coordination Center - EDACC (U01) RFA-RM-07-014**
PI Name	Institution Name	Title
BEAUDET, ARTHUR L. MILOSAVLJEVIC, ALEKSANDAR (contact)	BAYLOR COLLEGE OF MEDICINE	Epigenomics Data Analysis and Coordination Center at Baylor College of Medicine

**Developing Technologies for Improved In Vivo Epigenetic Imaging or Analysis (R01) RFA-RM-09-016**
PI Name	Institution Name	Title
GELOVANI, JURI G	UNIVERSITY OF TEXAS MD ANDERSON CAN CTR	Novel HDAC Class III Specific Radiotracers for PET Imaging
GREALLY, JOHN (contact) LEVY, MATTHEW	ALBERT EINSTEIN COL OF MED YESHIVA UNIV	In vivo imaging of X inactivation
HENIKOFF, STEVEN	FRED HUTCHINSON CANCER RESEARCH CENTER	Epigenomic profiling of histone turnover kinetics in mammalian cells
HOOKER, JACOB M	MASSACHUSETTS GENERAL HOSPITAL	Design of Class-specific HDAC Imaging Probes for Positron Emission Tomography
KERPPOLA, TOM	UNIVERSITY OF MICHIGAN AT ANN ARBOR	Visualization of Combinatorial Epigenetic Marks and Complexes in Animals Using Fl
LAIRD, PETER W	UNIVERSITY OF SOUTHERN CALIFORNIA	Visualizing the effect of epigenetic modifications on transcription and mutation
LIS, JOHN THOMAS (contact) CRAIGHEAD, HAROLD G ZIPFEL, WARREN R LIN, HENING	CORNELL UNIVERSITY ITHACA	In vivo Detection and Imaging of Epigenetic Histone Modifications and Modifying E
LOMVARDAS, STAVROS (contact) LARABELL, CAROLYN A	UNIVERSITY OF CALIFORNIA SAN FRANCISCO	Devising New Technologies for Live Imaging of Epigenetic Processes
YOUNG, WON-BIN (contact) AHRENS, ERIC T	CARNEGIE-MELLON UNIVERSITY	In Vivo Visualization and Quantification of Epigenetic Activities Using Magnetic

**Technology Development in Epigenetics (R21) RFA-RM-07-012**
PI Name	Institution Name	Title
GOZANI, OR P. (Contact) BEDFORD, MARK T	STANFORD UNIVERSITY	Applying peptide and protein domain microarrays to epigenetic research
HANG, HOWARD C	ROCKEFELLER UNIVERSITY	Chemical Reporters for the Analysis of Lysine Methylation in Epigenetics
HENIKOFF, STEVEN	FRED HUTCHINSON CANCER RESEARCH CENTER	Genome-wide measurement of histone replacement rates: a new dimension in epigenom
KOIDE, SHOHEI	UNIVERSITY OF CHICAGO	Novel affinity reagents for epigenetics markers
LIU, RIHE	UNIVERSITY OF NORTH CAROLINA CHAPEL HILL	Identification of the Interactome of Methylated Histones from Human Proteome

**Technology Development in Epigenetics (R01) RFA-RM-07-011**
PI Name	Institution Name	Title
CRAIGHEAD, HAROLD G SOLOWAY, PAUL D (contact)	CORNELL UNIVERSITY ITHACA	Epigenomic analysis on a nanoscale device
MITRA, ROBI D	WASHINGTON UNIVERSITY	METHYLMAP: A TECHNOLOGY TO ANALYZE PROMOTER METHYLATION IN MICRODISSECTED CELLS
ZHANG, KUN (Contact) SHI, HUIDONG	UNIVERSITY OF CALIFORNIA SAN DIEGO	Genome-scale anaylsis of DNA methylation in CpG Islands with bisulfite sequencing
TACKETT, ALAN (Contact) TAVERNA, SEAN D.	UNIVERSITY OF ARKANSAS MED SCIS LTL ROCK	Development of technology for high resolution epigenetic profiling of chromatin

**Discovery of Novel Epigenetic Marks in Mammalian Cells (R21) RFA-RM-07-016**
PI Name	Institution Name	Title
CHEN, XIAN STRAHL, BRIAN D (contact)	UNIVERSITY OF NORTH CAROLINA CHAPEL HILL	Identification of novel histone modifications in a model eukaryote
WARBURTON, PETER E	MOUNT SINAI SCHOOL OF MEDICINE OF NYU	Non-coding RNAs in the epigenetics of human centromere formation

**Discovery of Novel Epigenetic Marks in Mammalian Cells (R01) RFA-RM-07-015**
PI Name	Institution Name	Title
CHENG, XIAODONG	EMORY UNIVERSITY	Identification and characterization of novel epigenetic marks of non-histone prot
GRANT, PATRICK A	UNIVERSITY OF VIRGINIA CHARLOTTESVILLE	Characterization of a novel histone H3 phosphorylation mark in DNA replication
KATZ, RICHARD ALAN	INSTITUTE FOR CANCER RESEARCH	Discovery of Epigenetic Marks in Human Cells by High Throughput siRNA Screening
OETTINGER, MARJORIE A	MASSACHUSETTS GENERAL HOSPITAL	Is symmetrical dimethylation of Arginine 2 of Histone H3 used as an epigenetic si
TULIN, ALEXEI V ZARET, KENNETH S (contact)	INSTITUTE FOR CANCER RESEARCH	Novel Epigenetic Marks in Mitosis
ZHAO, YINGMING	UNIVERSITY OF TEXAS SW MED CTR/DALLAS	Systematic screening for new histone marks

This page last reviewed on October 12, 2018

Epigenomics

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