Epigenetics of Human Health and Disease
March 19-20, 2007, Bethesda North Marriott Hotel & Conference Center
Monday, March 19, 2007 | |
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8:00 a.m. | Registration |
8:30 - 8:50 a.m. | Welcome and Charge to the Group David A. Schwartz, M.D. Director National Institute of Environmental Health Sciences (NIEHS) Nora D. Volkow, M.D. Director National Institute on Drug Abuse (NIDA) |
8:50 - 9:00 a.m. | Introductions |
9:00 - 9:30 a.m. | Phenotypic Plasticity and the Epigenetics of Human Disease Andrew P. Feinberg, M.D., Ph.D. Johns Hopkins University School of Medicine |
9:30 - 9:45 a.m. | Break |
9:45 - 11:00 a.m. | Scientific Session 1: Applications to Human Health and Disease How Can the Application of Epigenetic Approaches Advance Our Understanding of Disease Susceptibility and Pathogenesis? |
9:45 - 10:10 a.m. | Mixed Epigenetic/Genetic and De novo/Inherited (MEGDI) Models of Disease Arthur L. Beaudet, M.D. Baylor College of Medicine |
10:10 - 10:35 a.m. | Epigenetics and Autoimmunity Bruce Richardson, M.D., Ph.D. University of Michigan |
10:35 - 11:00 a.m. | Epigenetic Mechanisms of Drug Addiction Eric J. Nestler, M.D., Ph.D. University of Texas, Southwestern |
11:00 - 11:15 a.m. | Break |
11:15 - 12:30 p.m. | Scientific Session 2: The State of Epigenetic Technology What Technologies and Investigative Approaches to Research Are Available and Likely To Be of Value in Epigenetics? |
11:15 - 11:40 a.m. | Overview of Epigenetic Analysis Technologies Peter W. Laird, Ph.D. University of Southern California |
11:40 a.m. - 12:05 p.m. | Genome-wide Transcription Maps Reveal Interleaved Organization and Possible Functions for Pervasive Transcription Thomas R. Gingeras, Ph.D. Affymetrix, Inc. |
12:05 - 12:30 p.m. | Mapping the Genome's Second Code Bing Ren, Ph.D. University of California, San Diego |
12:30 - 1:45 p.m. | Lunch (on your own) |
1:45 - 2:45 p.m. | Overview: International and U.S. Epigenetics Programs and Resources |
1:45 - 2:00 p.m. | European Epigenetics Programs Stephan Beck, Ph.D. Wellcome Trust Sanger Institute |
2:00 - 2:15 p.m. | Epigenetics Bioinformatics Resources Paul Flicek, D.Sc. European Bioinformatics Institute |
2:15 - 2:30 p.m. | Canadian Epigenetics Programs Art Petronis, M.D., Ph.D. University of Toronto |
2:30 - 2:45 p.m. | Epigenetics and the ENCODE Project Elise A. Feingold, Ph.D. National Human Genome Research Institute |
2:45 - 3:00 p.m. | Break |
3:00 - 3:10 p.m. | Criteria for Roadmap Proposals Elizabeth Wilder, Ph.D. Office of Portfolio Analysis and Strategic Initiatives (OPASI) |
3:10 - 5:10 p.m. | Breakout Session 1: Generation of Epigenetics Suggestions Breakout Discussion Group A Chair: David Schwartz, M.D., NIEHS Director Presenter: Steven Baylin, M.D. Breakout Discussion Group B Chair: Nora Volkow, M.D., NIDA Director Presenter: Donata Vercelli, M.D. Breakout Discussion Group C Chair: James Battey, M.D., Ph.D., NIDCD Director Presenters: Randy Jirtle, Ph.D. and Jim Ostell, Ph.D. |
3:10 - 3:50 p.m. | Generate three novel Roadmap suggestions for epigenetics research that could transform the biology of human health and disease, encompassing translational and clinically-oriented approaches. |
3:50 - 4:30 p.m. | Generate three novel Roadmap suggestions for tools and resources that could transform epigenetics research. |
4:30 - 5:10 p.m. | Generate three novel Roadmap suggestions for technological and bioinformatics needs that could transform epigenetics research. |
5:10 - 5:25 p.m. | Break |
5:25 - 5:40 p.m. | Breakout Group A Report Presenter: Steven Baylin, M.D. |
5:40 - 5:55 p.m. | Breakout Group B Report Presenter: Donata Vercelli, M.D. |
5:55 - 6:10 p.m. | Breakout Group C Report Presenters: Randy Jirtle, Ph.D. and Jim Ostell, Ph.D. |
6:10 - 6:30 p.m. | Group Discussion Facilitators: James Battey, M.D., Ph.D., Andrew Feinberg, M.D., Ph.D. and Jim Ostell, Ph.D. |
6:30 - 6:45 p.m. | Response to Suggestions David Schwartz, M.D., NIEHS Director Nora Volkow, M.D., NIDA Director |
6:45 p.m. | Adjournment |
Tuesday, March 20, 2007 | ||
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7:30 a.m. | Registration | |
8:00 - 9:45 a.m. | Breakout Session 2: Implementation of Suggestions | |
8:00 - 8:35 a.m. | Implement a suggestion for a technology/bioinformatics opportunity that could transform epigenetics research. | |
8:35 - 9:10 a.m. | Implement a suggestion for a tool or resource that could transform epigenetics research. | |
9:10 - 9:45 a.m. | Implement a suggestion for an application of epigenetics that could transform biology or treatment of disease. | |
9:45 - 10:00 a.m. | Break | |
10:00 - 10:20 a.m. | Breakout Group A Report Presenter: Steven Baylin, M.D. |
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10:20 - 10:40 a.m. | Breakout Group B Report Presenter: Donata Vercelli, M.D. |
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10:40 - 11:00 a.m. | Breakout Group C Report Presenters: Randy Jirtle, Ph.D. and Jim Ostell, Ph.D. |
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11:00 - 11:15 a.m. | Break | |
11:15 a.m. - 12:15 p.m. | Group Discussion and Refinement of Suggestions Facilitators: James Battey, M.D., Ph.D., Andrew Feinberg M.D., Ph.D. and Jim Ostell, Ph.D. |
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12:15 - 12:30 p.m. | Response to Suggestions and Closing Remarks David Schwartz, M.D., NIEHS Director Nora Volkow, M.D., NIDA Director |
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12:30 p.m. | Adjournment |
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