High-Risk, High-Reward Research (HRHR)
High-Risk, High-Reward Research (HRHR)
The agenda for the 2024 High-Risk, High-Reward Research (HRHR) Symposium is not yet available but will be posted when it is set. The agenda from the past 2023 HRHR Symposium is posted below.
2023 HRHR Symposium
June 8-9, 2023
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Thursday, June 8, 2023
| 9:00 AM - 9:15 AM | Trish Labosky, NIH Welcome & Opening Remarks |
Session 1 |
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|---|---|
| 9:15 AM - 9:35 AM | Yongxin Zhao, Carnegie Mellon University New Innovator Award Magnify: Next Generation Expansion Microscopy with a Universal Molecule Anchoring Strategy, the Applications and Beyond |
| 9:35 AM - 9:55 AM | Hsiao-Tuan Chao, Baylor College of Medicine Early Independence Award Cerebellar Dysfunction in Autism Spectrum and Neurodevelopmental Disorders: From Discovery Genetics to Translational Neuroscience |
| 9:55 AM - 10:15 AM | Nikhil Malvankar, Yale University New Innovator Award Wiring Cells: Control of Microbial Electron Export Using Natural and Synthetic Protein Nanowires |
| 10:15 AM - 10:35 AM | Break |
Session 2 |
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| 10:35 AM - 10:55 AM | Jennifer Elisseeff, Johns Hopkins University Pioneer Award Biomaterials-Directed Regenerative Immunology |
| 10:55 AM - 11:15 AM | Andrew Leifer, Princeton University New Innovator Award Neural Signal Propagation Atlas of C. elegans |
| 11:15 AM - 11:35 AM | Siyuan Wang, Yale University School of Medicine New Innovator Award High-Content Image-Based CRISPR Screening Reveals Regulators of 3D Genome Architectures |
| 11:35 AM - 12:00 PM | Awardee Photo Shoot |
| 12:00 PM - 1:10 PM | Lunch (on your own) |
| 1:10 PM - 3:00 PM | Poster Session & NIH Office Hours |
Session 3 |
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| 3:00 PM - 3:20 PM | Brian Chait, The Rockefeller University Transformative Research Award Nature-Inspired Device for Next Generation Mass Spectrometry |
| 3:20 PM - 3:40 PM | Megan Dennis, University of California, Davis New Innovator Award Gene Expansions Contributing to Human Brain Evolution |
| 3:40 PM - 4:00 PM | Break |
Session 4 |
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| 4:00 PM - 4:20 PM | Daniel Gallego-Perez, The Ohio State University New Innovator Award Cell and Tissue Nanotransfection-Driven Therapies for Neurodegenerative Conditions and Metabolic Disorders |
| 4:20 PM - 4:40 PM | Gilad Evrony, NYU Grossman School of Medicine Early Independence Award Single-Molecule DNA Sequencing of Single-Strand Mismatch and Damage Patterns |
| 4:40 PM - 5:00 PM | Kendra Frederick, UT Southwestern New Innovator Award Structural Determination of Neurodegenerative Disease-Associated Proteins Inside Cells |
| 5:00 PM - 6:00 PM | Happy Hour |
Friday, June 9, 2023
Session 5 | |
|---|---|
| 8:30 AM - 8:45 AM | Robert Eisinger, NIH Opening Remarks |
| 8:45 AM - 9:05 AM | Christoph Thaiss, University of Pennsylvania New Innovator Award Body-Brain Communication: A New Frontier in Biomedicine |
| 9:05 AM - 9:25 AM | Arjun Raj, University of Pennsylvania Transformative Research Award How Do Cells Learn New Types? |
| 9:25 AM - 9:45 AM | Tara Deans, University of Utah New Innovator Award Utilizing Synthetic Biology to Advance Therapeutics |
| 9:45 AM - 10:05 AM | Courtney Yuen, Brigham and Women's Hospital New Innovator Award Improving the Equity of Community-Based Screening Programs Through Innovative Analytic Approaches |
| 10:05 AM - 10:25 AM | Break |
Session 6 | |
| 10:25 AM - 10:45 AM | Jerry Chen, Boston University New Innovator Award CRACKing Cortical Circuits Underlying Learning and Behavior |
| 10:45 AM - 11:05 AM | Anne-ruxandra Carvunis, University of Pittsburgh New Innovator Award From Non-Coding to Coding: Uncovering the Hidden Coding Potential of Non-Coding Sequences and Its Role in De Novo Gene Evolution |
| 11:05 AM - 11:25 AM | Jeffrey Macklis, Harvard University Pioneer Award Building, Maintaining, or Regenerating Diverse Brain Circuitry is Complex: Subtype-Specific and Dynamic Subcellular Molecular Machinery in Cerebral Cortex |
| 11:25 AM - 11:45 AM | Raymond Moellering, The University of Chicago New Innovator Award Direct Targeting of Oncogenic Transcription Factors with Synthetic Transcriptional Repressors |
| 11:45 AM - 12:05 PM | Medha Pathak, University of California, Irvine New Innovator Award A Novel Tool to Study Endogenous Human Piezo1 from Single Cells to Tissue Organoids |
| 12:05 PM - 1:10 PM | Lunch (on your own) |
| 1:10 PM - 3:00 PM | Poster Session & NIH Office Hours |
Session 7 | |
| 3:00 PM - 3:20 PM | Shixin Liu, The Rockefeller University New Innovator Award Machines on Genes: A Single-Molecule Perspective |
| 3:20 PM - 3:40 PM | Kamena Kostova, Carnegie Mellon University Early Independence Award Ribosomal Quality Control |
| 3:40 PM - 4:00 PM | Break |
Session 8 | |
| 4:00 PM - 4:20 PM | Jonathan Brestoff, Washington University School of Medicine Early Independence Award Mitochondria Transfer Rescues Aerobic Respiration in Metabolically Compromised Macrophages |
| 4:20 PM - 4:40 PM | Sabrina Spencer, University of Colorado-Boulder New Innovator Award Control of the Proliferation-Quiescence Decision at the Single-Cell Level |
| 4:40 PM - 5:00 PM | Sidi Chen, Yale University New Innovator Award Genome Engineering for, of, and as Immunotherapy |
| 5:00 PM - 5:10 PM | Trish Labosky, NIH Closing Remarks |
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