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Funded Research

National Technology Centers for Networks and Pathways

The Building Blocks, Biological Pathways and Networks program has transitioned from Common Fund support. For more information, please visit https://commonfund.nih.gov/bbpn/index. Please note that since the Building Blocks, Biological Pathways and Networks program is no longer supported by the Common Fund, the program website is being maintained as an archive and will not be updated on a regular basis.

Renewal of the National Technology Centers for Networks and Pathways Program (U54)
RFA-RM-08-021
PI NameInstitution NameTitle
BOEKE, JEF D.JOHNS HOPKINS UNIVERSITYNetworks, Pathways and Dynamics of Lysine Modification
ROUT, MICHAEL PROCKEFELLER UNIVERSITYNew Tools for Exploring the Dynamic Interactome (Renewal)
WAGGONER, ALAN SCARNEGIE-MELLON UNIVERSITYFluorescent Biosensors for Networks and Pathways

 

National Technology Centers for Networks and Pathways (U54)
RFA-RM-04-005
PI NameInstitution NameTitle
BOEKE, JEF DJOHNS HOPKINS UNIVERSITYNetworks and Pathways of Lysine Modification
SMITH, JEFFREY WBURNHAM INSTITUTECenter on Proteolytic Pathways

 

National Technology Centers for Networks and Pathways (Re-issuance) (U54)
RFA-RM-04-019
PI NameInstitution NameTitle
LOEW, LESLIE M.UNIVERSITY OF CONNECTICUT SCH OF MED/DNTPOLARITY IN NETWORKS AND PATHWAYS
ROUT, MICHAEL P.ROCKEFELLER UNIVERSITYNew Tools for Exploring the Dynamic Interactome
WAGGONER, ALAN S.MELLON PITTS CORPORATION (MPC CORP)Flourescent Probes & Imaging for Networks & Pathways

 

Metabolomics Technology Development

Using Metabolomics to Investigate Biological Pathways and Networks (R01)
RFA-RM-06-010
PI NameInstitution NameTitle
BURANT, CHARLES FUNIVERSITY OF MICHIGAN AT ANN ARBORUsing Systems Biology to Understand Islet Adaptation and Failure Diabetes
CRAVATT, BENJAMIN FSCRIPPS RESEARCH INSTITUTEChemical Probes for Metabolic Pathway Discovery in Human Disease
DOVICHI, NORMAN JUNIVERSITY OF WASHINGTONGlycolipid metabolism in single cells
FREYER, JAMES PLOS ALAMOS NAT SECTY-LOS ALAMOS NAT LABDifferential metabolic network analysis of tumor progression
FROMMER, WOLF BCARNEGIE INSTITUTION OF WASHINGTON, D.C.Sugar signaling networks detected by high content fluxomics
HAN, XIANLINWASHINGTON UNIVERSITYShotgun Lipidomics and Alterations in Sphingolipidomes in Alzheimer's Diseases
SWEEDLER, JONATHAN VUNIVERSITY OF ILLINOIS URBANA-CHAMPAIGNThe Neurometabolome of a Sensory Neuronal Network

 

Metabolomics Technology Development (R21, R33)
RFA-RM-04-002
PI NameInstitution NameTitle
BREAKER, RONALDYALE UNIVERSITYMeasuring Metabolites Using Riboswitch Reports
BROWN, TRUMAN RCOLUMBIA UNIVERSITY HEALTH SCIENCESMetabolic Patterns in 1H NMR Spectra of Biofluids
BRUNENGRABER, HENRICASE WESTERN RESERVE UNIVERSITYDynamic Metabolomics via Isotopomer Analysis
DOVICHI, NORMAN JUNIVERSITY OF WASHINGTONGLYCOLIPID METABOLISM IN SINGLE CELLS
GRIFFIN, JULIAN LUNIVERSITY OF CAMBRIDGEMetabolomics and Metabolomic Compartmentation in the Brain
HILL, HERBERT HWASHINGTON STATE UNIVERSITYHigh Resolution Ion Mobility Mass Spectrometry (IMMS)
KLEINFELD, ALAN MFFA SCIENCES, LLCFluorescent Probes for Hydrophobic Metabolites
LIAO, JAMES CUNIVERSITY OF CALIFORNIA LOS ANGELESAutomated Chip-Based Metabolic Analysis
MATSON, WAYNE RESA, INCIntegrating LCE/LCM In a Single Metabolomics Plataform
REGNIER, FRED EPURDUE UNIVERSITY WEST LAFAYETTETools for Differential Metabolomics
SUSSMAN, MICHAEL RUNIVERSITY OF WISCONSON MADISONIsotope-Assisted Differential Metabolomics
SWEEDLER, JONATHAN VUNIVERSITY OF ILLINOIS URBANA-CHAMPAIGNTechnologies for Cellular Neurometabolomics
WAGNER, GERHARDHARVARD UNIVERSITY (MEDICAL SCHOOL)Integrated & Sensitive Metabolomics Platform/Human disease
YORK, JOHN DDUKE UNIVERSITYBiological Oscilloscopes Spatio-Temporal Metabolomics

This page last reviewed on January 30, 2024