Funded Research

Notice of Special Interest (NOSI): Availability of Administrative Supplements to Accelerate Dissemination of Emerging Glycoscience Tools through Collaborations Between Developers and Early Adopters NOT-RM-20-003
PI Name Institution Name Title
ATKINSON, CARL MEDICAL UNIVERSITY OF SOUTH CAROLINA Complement-driven innate and adaptive autoreactivity in lung transplantation
CHU, JAIME ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Mannose metabolism as a regulator of hepatic stellate cell activation and fibrosis

MOHAMED, ABEER M

 UNIVERSITY OF ILLINOIS AT CHICAGO Shedding of Endothelial Glycocalyx in Morbidly Obese Patients
NIU, JIA BOSTON COLLEGE Development of Compact CRISPR Editors for Multiplexed Editing of Complex Gene Networks
PETERSEN, CHRISTINE A (contact)
GOMES-SOLECKI, MARIA		 UNIVERSITY OF IOWA Field trial and modeling of transmission blocking vaccine to prevent Lyme disease
SCHNABL, BERND G. (contact)
ECKMANN, LARS		 UNIVERSITY OF CALIFORNIA, SAN DIEGO San Diego Digestive Diseases Research Center
SHAPIRO, VIRGINIA SMITH MAYO CLINIC ROCHESTER ST8Sia6 expression on tumors inhibits the immune response
SHARMA, KUMAR UNIVERSITY OF TEXAS HLTH SCIENCE CENTER Spatial Metabolomics for Human Kidneys
SMITH, LACHLAN JAMES UNIVERSITY OF PENNSYLVANIA Pathogenesis and Treatment of Bone Disease in the Mucopolysaccharidoses
THURMAN, JOSHUA M UNIVERSITY OF COLORADO DENVER Complement-mediated injury of the kidney: New mechanisms and novel therapies
TIEMEYER, MICHAEL (contact)
MAZUMDER, RAJA		 UNIVERSITY OF GEORGIA GlyGen Supplement: Develop automatic literature mining tool for extracting context specific glycan-protein data that will enhance the extent and quality of data in GlyGen

 

Notice of Special Interest (NOSI): Accelerate Dissemination of Emerging Glycoscience Tools through Collaborations Between Developers and Early Adopters (Admin Supp) NOT-RM-19-012
PI Name Institution Name Title
BLENIS, JOHN WEILL MEDICAL COLL OF CORNELL UNIV Mitogenic and ocogenic regulation of ERK/RSK signaling
MINEO, CHIEKO UT SOUTHWESTERN MEDICAL CENTER Endothelial basis of obesity-induced insulin resistance 
RAJARATHNAM, KRISHNA (contact)
CHOPRA, ASHOK K		 UNIVERSITY OF TEXAS MEDICAL BRANCH AT GALVESTO Engineered chemokines as therapeutics for bacterial infections
RUIZ, NATIVIDAD OHIO STATE UNIVERSITY Envelope Biogenesis in Gram-negative Bacteria
SCHMIDT, ERIC PETER (contact)
HERSON, PACO S		 UNIVERSITY OF COLORADO DENVER Targeting circulating endothelial glycocalyx fragments to reduce septic encephalopathy
SCOTT, MELANIE J UNIVERSITY OF PITTSBURG Inflammasome activation in trauma-hemorrhagic shock
SAXENA, RICHA MASSACHUSETTS GENERAL HOSPITAL Genetics of chronotype and impact on metabolic disease

 

Novel and innovative tools to facilitate identificiation, manipulation, and analysis of glycans and their functions (U01) RFA-RM-18-036
PI Name Institution Name Title
BUELOW, HANNES ERICH (contact)
STEIDL, ULRICH G		 ALBERT EINSTEIN COLLEGE OF MEDICINE, INC  A Fluorescence-Based High-Throughput Platform for Glycotyping the Hematopoetic Cell Lineage
KOHLER, JENNIFER J UT SOUTHWESTERN MEDICAL CENTER New Tools for Studying GlcNAc Biology
SCHNAAR, RONDALD L JOHNS HOPKINS UNIVERSITY Ganglioside Interactome Toolkit
STOWELL, SEAN R (contact)
CUMMINGS, RICHARD D		 EMORY UNIVERSITY Integrating Microbial Glycan Arrays with Genomic Sequences to Study Host Microbe Interactions
WOO, CHRISTINA HARVARD UNIVERISTY Tools to Facilitate Manipulation of Protein-Specific Glycosylation Stoichiometry in Cells

 

Innovative Adaptations to Simplify Existing technologies for Manipulation and Analysis of Glycans (U01) RFA-RM-18-037
PI Name Institution Name Title
DESAI, UMESH RAMANLAL VIRGINIA COMMONWEALTH UNIVERSITY Tool for Predicting Glycosaminoglycan Recognition of Proteins
DRAKE, RICHARD R (contact)
ANGEL, PEGGY M
MEHTA, ANAND S		 MEDICAL UNIVERSITY OF SOUTH CAROLINA Simplified Glycan Profiling Workflows of Captured Immune Glycoproteins and Cells

 

Innovative Adaptations to Simplify Existing technologies for Manipulation and Analysis of Glycans (U01) RFA-RM 17-029
PI Name Institution Name Title
AMSTER, I JONATHAN UNIVERSITY OF GEORGIA An Automated Platform for the CE-MS Analysis of Glycosaminoglycans
GOLDMAN, RADOSLAV (contact) 
EDWARDS, NATHAN J 		 GEORGETOWN UNIVERSITY LC-MS Analysis of Site Specific Protein Glycoforms

 

Novel and innovative tools to facilitate identification, tracking, manipulation, and analysis of glycans and their functions (U01) RFA-RM 17-030
PI Name Institution Name Title
AI, HUIWANG  UNIVERSITY OF VIRGINIA BapaFPs: Genetically encoded fluorescent indicators to image live-cell nucleotide sugars
BALAGURUNATHAN, KUBERAN UNIVERSITY OF UTAH Manipulating Glycosaminoglycans Using Synthetic Xylosides to Regulate Angiogenesis
KIESSLING, LAURA L (contact) 
IMPERIALI, BARBARA 		 MASSACHUSETTS INSTITUTE OF TECHNOLOGY Development of multifunctional probes for profiling microbial glycans
LI, LINGJUN  UNIVERSITY OF WISCONSIN-MADISON MULTIPLEX CHEMICAL TAGS FOR HIGH-THROUGHPUT GLYCAN AND GLYCOPEPTIDE QUANTITATION AND CHARACTERIZATION
LINSTEDT, ADAM D CARNEGIE-MELLON UNIVERSITY Cell-Based Sensors and Drug-Like Moldulators Targeting ppGalNAc-Transferases
ZACHARA, NATASHA ELIZABETH  JOHNS HOPKINS UNIVERSITY Tuning and Tagging the O-GlcNAc Modification

 

Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-16-020
PI Name Institution Name Title
CRICH, DAVID WAYNE STATE UNIVERSITY Novel Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates
MONTGOMERY, JOHN (contact) 
NAGORNY, PAVEL 
SHERMAN, DAVID H 		 UNIVERSITY OF MICHIGAN Catalytic Methods for Building Block Assembly and for Stereoselective Glycosylation
TANG, WEIPING UNIVERSITY OF WISCONSIN-MADISON Develop Catalytic Methods to Streamline the Assembly of Oligosaccharides
WALCZAK, MACIEJ ANDRZEJ UNIVERSITY OF COLORADO New Catalytic Methods for the Synthesis of Biomedically Relevant Carbohydrates
YU, HAI (contact) 
KIESSLING, LAURA L 
LI, LEI		 UNIVERSITY OF CALIFORNIA AT DAVIS Chemoenzymatic synthesis of bacterial polysaccharides
ZHANG, LIMING (contact) 
ZHU, JIANGLONG		 UNIVERSITY OF CALIFORNIA SANTA BARBARA Development of novel approaches for stereoselective construction of glycosidic linkages

 

Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Data in the Context of Comparable Gene, Protein, and Lipid Data (U01) RFA-RM-16-021
PI Name Institution Name Title
YORK, WILLIAM S (contact) 
MAZUMDER, RAJA		 UNIVERSITY OF GEORGIA Computational and Informatics Resources and Tools for Glycoscience Research

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-16-022
PI Name Institution Name Title
GRIMES, CATHERINE LEIMKUHLER UNIVERSITY OF DELAWARE Metabolic carbohydrate cell wall probes for bacterial structure and immune recognition studies
MAHAL, LARA K NEW YORK UNIVERSITY GlycoMiR: Mapping the miRNA-glycogene interactome
RUHL, STEFAN HANS-KLAUS (contact) 
SULLAM, PAUL M.		 STATE UNIVERSITY OF NEW YORK AT BUFFALO HARNESSING THE ORAL MICROBIOME TO CREATE NOVEL GLYCAN-BINDING PROBES
SHE, JIN-XIONG AUGUSTA UNIVERSITY Luminex multiplex glycan array (LMGA): a high throughput and high content platform for GBPs
WANG, XU  ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Sequencing Glycosaminoglycans using Recognition Tunneling Nanopores
ZAIA, JOSEPH  BOSTON UNIVERSITY MEDICAL CAMPUS An open-source software suite for processing glycomics and glycoproteomics mass spectral data

 

Innovative Adaptations to Simplify Existing Technologies for Manipulation and Analysis of Glycans (U01) RFA-RM-16-023
PI Name Institution Name Title
REINHOLD, VERNON NYE UNIVERSITY OF NEW HAMPSHIRE Shaping MSn Technology for High Impact Glycan Sequencing
WOODS, ROBERT J (contact) 
YOUNG, JASMINE Y 		 UNIVERSITY OF GEORGIA GlyProbity: tools to curate glycan structure pre and post deposition in the PDB
YANG, LORETTA GLYCOSENSORS AND DIAGNOSTICS, LLC Adapting multiplex microspheres to analyze glycosylation features by flow cytometry

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (R21) RFA-RM-15-008
PI Name Institution Name Title
AMSTER, I JONATHAN UNIVERSITY OF GEORGIA Rapid Sequencing of Sulfated Glycans By CE-MS/MS
AZADI, PARASTOO  UNIVERSITY OF GEORGIA Glycan linkage and sequence plus determination of site of glycosylation by permethylation of glycopeptides and MSn analysis in a one pot experiment
BERN, MARSHALL WAYNE PROTEIN METRICS, INC. Glycopeptide Identification with a Comprehensive Proteomics Search Engine
DRAKE, RICHARD R.
 		 MEDICAL UNIVERSITY OF SOUTH CAROLINA Detection and Histopathology Localization of O-Glycans and Glycosaminoglycans in Tissues
GHIRLANDA, GIOVANNA (contact) 
OZKAN, SEFIKA BANU		 ARIZONA STATE UNIVERSITY-TEMPE CAMPUS New Tools for Glycoscience: Engineering Targeted Lectins by Computer-Guided Directed Evolution
GODULA, KAMIL (contact) 
GAGNEUX, PASCAL		 UNIVERSITY OF CALIFORNIA SAN DIEGO Glycan array for phenotype-driven capture and genotyping of viruses in primary isolates
HAAB, BRIAN B. VAN ANDEL RESEARCH INSTITUTE On-chip Glycan Analysis of Clinical Specimens
HILI, RYAN UNIVERSITY OF GEORGIA Functionalized DNA as glycan recognition molecules
KOHLER, JENNIFER J UT SOUTHWESTERN MEDICAL CENTER Photocrosslinking probes to discover glycan-dependent interactions
LI, LINGJUN  UNIVERSITY OF WISCONSIN-MADISON    Mass Defect-based Chemical Tags for Multiplex Glycan Quantitation
LIN, CHENG BOSTON UNIVERSITY MEDICAL CAMPUS Characterization of glycan isomers by trapped ion mobility spectrometry-electron activated dissociation tandem mass spectrometry
LINSTEDT, ADAM D CARNEGIE-MELLON UNIVERSITY DRUG-LIKE MODULATORS TARGETING O-GLYCOSYLATION BY GalNAc TRANSFERASE-2/3
NYCHOLAT, CORWIN MICHAEL SCRIPPS RESEARCH INSTITUTE Developing high affinity ligands of glycan binding proteins
RANZINGER, RENE (contact) 
AOKI, KAZUHIRO		 UNIVERSITY OF GEORGIA Development of high-throughput workflow for glycosphingolipid analysis and annotation
SONG, XUEZHENG EMORY UNIVERSITY Next generation glycan microarray (NGGM) enabled by next generation sequencing (NGS) and DNA-coded glycan library
TEYTON, LUC SCRIPPS RESEARCH INSTITUTE Production of high affinity anti-glycan and anti-glycolipid antibodies
ZENG, YONG UNIVERSITY OF KANSAS LAWRENCE Integrated Digital Microfluidic Platforms for Next-Generation Glycomics

 

Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-15-007
PI Name Institution Name Title
BENNETT, CLAY SAMUEL TUFTS UNIVERSITY MEDFORD Reagent Control for Stereoselective Glycosylation Reactions
BOONS, GEERT-JAN UNIVERSITY OF GEORGIA Streamlining the chemoenzymatic synthesis of asymmetrical glycans of biological importance
BRICHACEK, MATTHEW PAUL UNIVERSITY OF MAINE ORONO Transformative Methods for the Solid Phase Synthesis of Oligosaccharides
CHEN, XI (contact) 
WANG, PENG GEORGE		 UNIVERSITY OF CALIFORNIA AT DAVIS Facile chemoenzymatic synthesis and purification of glycolipids
DEMCHENKO, ALEXEI V (contact) 
DE MEO, CRISTINA  
STINE, KEITH J.		 UNIVERSITY OF MISSOURI-ST. LOUIS Refinement and implementation of the automated oligosaccharide synthesizer
NGUYEN, HIEN M UNIVERSITY OF IOWA Catalytic Methods for Stereoselective 1,2-Cis Glycosylation

 

Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-15-009
PI Name Institution Name Title
BERTOZZI, CAROLYN R (contact) 
PITTERI, SHARON 		 STANFORD UNIVERSITY Making glycoproteomics via mass spectrometry more accessible to the greater scientific community
JU, TONGZHONG EMORY UNIVERSITY Novel Technologies for Quantitative O-glycomics and Amplification/Preparation of Cellular O-Glycans
WOODS, ROBERT J (contact) 
FOLEY, B. LACHELE		 UNIVERSITY OF GEORGIA Tools to enable non-specialists to model glycoconjugates and glycan-protein interactions

 

Data Integration and Analysis Tools: Accessible Resources for Integration and Analysis of Carbohydrate and Glycoconjugate Structural, Analytical, and Interaction Data in the Context of Comparable Gene, Protein, and Lipid Data (R34) RFA-RM-14-012
PI Name Institution Name Title
MAZUMDER, RAJA GEORGE WASHINGTON UNIVERSITY GlycoCentral: Glycobiology data and tool integration with genes, proteins and lipids
YORK, WILLIAM S. UNIVERSITY OF GEORGIA glySpace: an integrated infrastructure for Glycoinformatics

 

 
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (U01) RFA-RM-14-013
PI Name Institution Name Title
CUMMINGS, RICHARD D (contact) 
MERNAUGH, RAYMOND L		 BETH ISRAEL DEACONESS MEDICAL CENTER Smart Anti-Glycan Reagents to Generate the Human Glycome Atlas
VARKI, AJIT P UNIVERSITY OF CALIFORNIA SAN DIEGO Sialoglycan-Recognizing Probes for Defining Sialoglycomes in Biological Systems

 

 
Novel and Innovative Tools to Facilitate Identification, Tracking, Manipulation, and Analysis of Glycans and their Functions (R21) RFA-RM-14-014
PI Name Institution Name Title
BERTOZZI, CAROLYN R STANFORD UNIVERSITY Revolutionizing the detection of O-GlcNAc
COBB, BRIAN A (contact) 
ABBOTT, DEREK W		 CASE WESTERN RESERVE UNIVERSITY Glycome-Enhanced KnockOut (GEKO) Technology
COON, JOSHUA J UNIVERSITY OF WISCONSIN-MADISON Activated-Ion Negative Electron Transfer Dissociation For High-Throughput Glycoproteomics
NOVOTNY, MILOS INDIANA UNIVERSITY New Chromatographic Technologies for Resolving Carbohydrate Isomers
RUHL, STEFAN HANS-KLAUS (contact) 
SULLAM, PAUL M.		 STATE UNIVERSITY OF NEW YORK AT BUFFALO MINING THE ORAL MICROBIOME FOR NOVEL GLYCAN-BINDING MOLECULES
SHE, JIN-XIONG GEORGIA REGENTS RESEARCH INSTITUTE INC Multiplex Luminex glycan array for large scale analyses of glycan-binding proteins
STOJANOVIC, MILAN N COLUMBIA UNIVERSITY HEALTH SCIENCES Automated Microfluidic Selection of Aptamers against Carbohydrates
TANG, KEQI BATTELLE PACIFIC NORTHWEST LABORATORIES A hybrid IMS-MS platform for ultrasensitive and high resolution glycan analysis
WANG, LIANCHUN UNIVERSITY OF GEORGIA Using CRISPR-Cas9 technology to develop a mutant cell library for heparan sulfate structure-function study
WANG, XU ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Single Molecule Sequencing of Glycosaminoglycans using Recognition Tunneling Nanopores
WEST, CHRISTOPHER M. (contact) 
TARLETON, RICK L 
WELLS, LANCE		 UNIVERSITY OF GEORGIA Enabling tools for protists pathogen glycobiology
ZACHARA, NATASHA ELIZABETH JOHNS HOPKINS UNIVERSITY Chemical Genetic Tools for the Spatial and Temporal Modulation of O-GlcNAcylation
ZAIA, JOSEPH BOSTON UNIVERSITY Software for automated interpretation of heparan sulfate tandem mass spectra

 

 
Facile Methods and Technologies for Synthesis of Biomedically Relevant Carbohydrates (U01) RFA-RM-14-015
PI Name Institution Name Title
CHAIKOF, ELLIOT (contact) 
CUMMINGS, RICHARD D		 BETH ISRAEL DEACONESS MEDICAL CENTER Facile Synthesis of Glycosulfopeptides and Related Bioconjugates
HSIEH-WILSON, LINDA C (contact) 
HUANG, XUEFEI		 CALIFORNIA INSTITUTE OF TECHNOLOGY Expedited Synthesis of Glycosaminoglycans Containing Defined Sulfation Domains

JACOBSEN, ERIC N

 HARVARD COLLEGE Small-Molecule Catalysts for the Stereoselective Synthesis of Oligosaccharides
POHL, NICOLA L INDIANA UNIVERSITY Sugar Building Blocks and Automated Synthesis of Biomedically-Relevant Glycans
SONG, XUEZHENG (contact) 
REINHOLD, VERNON NYE		 EMORY UNIVERSITY Facile Chemical Methods for Reverse Synthesis and Large Scale Production of Biomedically Relevant Glycan Libraries
WANG, PENG GEORGE (contact) 
LI, LEI		 GEORGIA STATE UNIVERSITY Facile Synthesis of O-Glycans and O-Glycopeptides

 


 

This page last reviewed on June 21, 2021